HK1034511A1 - Heterocyclic compounds having nos inhibitory activities - Google Patents
Heterocyclic compounds having nos inhibitory activitiesInfo
- Publication number
- HK1034511A1 HK1034511A1 HK01104945A HK01104945A HK1034511A1 HK 1034511 A1 HK1034511 A1 HK 1034511A1 HK 01104945 A HK01104945 A HK 01104945A HK 01104945 A HK01104945 A HK 01104945A HK 1034511 A1 HK1034511 A1 HK 1034511A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- heterocyclic compounds
- inhibitory activities
- nos inhibitory
- nos
- activities
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33926797 | 1997-11-04 | ||
| JP14649298 | 1998-04-20 | ||
| PCT/JP1998/004967 WO1999023069A1 (fr) | 1997-11-04 | 1998-11-04 | Composes heterocycliques a activites inhibant nos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1034511A1 true HK1034511A1 (en) | 2001-10-26 |
Family
ID=26477320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK01104945A HK1034511A1 (en) | 1997-11-04 | 2001-07-16 | Heterocyclic compounds having nos inhibitory activities |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6414005B1 (xx) |
| EP (1) | EP1043312A4 (xx) |
| KR (1) | KR100384046B1 (xx) |
| CN (1) | CN1217928C (xx) |
| AU (1) | AU737967B2 (xx) |
| CA (1) | CA2307581C (xx) |
| HK (1) | HK1034511A1 (xx) |
| TW (1) | TW460460B (xx) |
| WO (1) | WO1999023069A1 (xx) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005071269A (ja) * | 2003-08-27 | 2005-03-17 | Fuji Photo Film Co Ltd | カレンダタイマ機構、医療用画像処理システム、医療用プリントシステム、制御プログラム及び制御プログラムを記録する記録媒体 |
| PE20070341A1 (es) * | 2005-07-29 | 2007-04-13 | Wyeth Corp | Derivados de pirrol como moduladores del receptor de progesterona |
| PE20070182A1 (es) * | 2005-07-29 | 2007-03-06 | Wyeth Corp | Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona |
| EP1942105B8 (en) | 2005-10-25 | 2014-08-13 | Shionogi&Co., Ltd. | Aminodihydrothiazine derivative |
| US8653067B2 (en) | 2007-04-24 | 2014-02-18 | Shionogi & Co., Ltd. | Pharmaceutical composition for treating Alzheimer's disease |
| KR20100017255A (ko) | 2007-04-24 | 2010-02-16 | 시오노기 앤드 컴파니, 리미티드 | 환식기로 치환된 아미노다이하이드로싸이아진 유도체 |
| US8637504B2 (en) | 2008-06-13 | 2014-01-28 | Shionogi & Co., Ltd. | Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity |
| EP2360155A4 (en) | 2008-10-22 | 2012-06-20 | Shionogi & Co | 2-AMINOPYRIDIN-4-ON AND 2-AMINOPYRIDINE DERIVATIVE WITH BACE1-HEMDERING EFFECT |
| JPWO2010113848A1 (ja) * | 2009-03-31 | 2012-10-11 | 塩野義製薬株式会社 | Ｂａｃｅ１阻害作用を有するイソチオウレア誘導体またはイソウレア誘導体 |
| RU2012129168A (ru) | 2009-12-11 | 2014-01-20 | Сионоги Энд Ко. Лтд. | Производные оксазина |
| JP5766198B2 (ja) | 2010-10-29 | 2015-08-19 | 塩野義製薬株式会社 | 縮合アミノジヒドロピリミジン誘導体 |
| CA2816285A1 (en) | 2010-10-29 | 2012-05-03 | Shionogi & Co., Ltd. | Naphthyridine derivative |
| CN103608345A (zh) | 2011-04-26 | 2014-02-26 | 盐野义制药株式会社 | 噁嗪衍生物和含有该噁嗪衍生物的bace1抑制剂 |
| WO2014065434A1 (en) | 2012-10-24 | 2014-05-01 | Shionogi & Co., Ltd. | Dihydrooxazine or oxazepine derivatives having bace1 inhibitory activity |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1209431B (it) * | 1980-11-28 | 1989-07-16 | Angeli Inst Spa | Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione. |
| US5223526A (en) * | 1991-12-06 | 1993-06-29 | Monsanto Company | Pyrazole carboxanilide fungicides and use |
| US5639770A (en) | 1992-05-29 | 1997-06-17 | Otsuka Pharmaceutical Co., Ltd. | Thiazole derivatives |
| JP3385387B2 (ja) * | 1992-05-29 | 2003-03-10 | 大塚製薬株式会社 | チアゾール誘導体 |
| BR9407515A (pt) * | 1993-08-12 | 1997-01-07 | Astra Ab | Composto formulação farmaceutica uso do composto processos para o tratamento de desordens neurodegenerativas ou de enxaqueca ou para a prevenção e a reversão da tolerância aos opiatos e diazepinas ou para o tratamento do vicio das drogas e para a preparação do composto |
| GB9425701D0 (en) * | 1994-12-20 | 1995-02-22 | Wellcome Found | Enzyme inhibitors |
| US5629335A (en) * | 1995-04-07 | 1997-05-13 | Rhone-Poulenc Inc. | Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters |
| ATE219764T1 (de) * | 1996-03-29 | 2002-07-15 | Searle & Co | Zimtsäurederivate und deren verwendung als integrin-antagonisten |
| US5668159A (en) * | 1996-05-08 | 1997-09-16 | The Dupont Merck Pharmaceutical Company | 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as IIb/IIIa antagonists |
| AU2978197A (en) * | 1996-06-04 | 1998-01-05 | Chugai Seiyaku Kabushiki Kaisha | Substituted benzenes having nos inhibitory effects |
-
1998
- 1998-11-02 TW TW087118206A patent/TW460460B/zh active
- 1998-11-04 CN CN988116944A patent/CN1217928C/zh not_active Expired - Fee Related
- 1998-11-04 AU AU97614/98A patent/AU737967B2/en not_active Ceased
- 1998-11-04 EP EP98951681A patent/EP1043312A4/en not_active Withdrawn
- 1998-11-04 WO PCT/JP1998/004967 patent/WO1999023069A1/ja not_active Application Discontinuation
- 1998-11-04 KR KR10-2000-7004872A patent/KR100384046B1/ko not_active IP Right Cessation
- 1998-11-04 US US09/530,752 patent/US6414005B1/en not_active Expired - Fee Related
- 1998-11-04 CA CA002307581A patent/CA2307581C/en not_active Expired - Fee Related
-
2001
- 2001-07-16 HK HK01104945A patent/HK1034511A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU737967B2 (en) | 2001-09-06 |
| CA2307581C (en) | 2005-10-18 |
| EP1043312A4 (en) | 2001-01-17 |
| WO1999023069A1 (fr) | 1999-05-14 |
| KR100384046B1 (ko) | 2003-07-16 |
| US6414005B1 (en) | 2002-07-02 |
| CA2307581A1 (en) | 1999-05-14 |
| TW460460B (en) | 2001-10-21 |
| EP1043312A1 (en) | 2000-10-11 |
| AU9761498A (en) | 1999-05-24 |
| CN1280565A (zh) | 2001-01-17 |
| KR20010031803A (ko) | 2001-04-16 |
| CN1217928C (zh) | 2005-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20091104 |