HK1034266A1 - Antithrombotic compounds - Google Patents

Antithrombotic compounds

Info

Publication number
HK1034266A1
HK1034266A1 HK01104760A HK01104760A HK1034266A1 HK 1034266 A1 HK1034266 A1 HK 1034266A1 HK 01104760 A HK01104760 A HK 01104760A HK 01104760 A HK01104760 A HK 01104760A HK 1034266 A1 HK1034266 A1 HK 1034266A1
Authority
HK
Hong Kong
Prior art keywords
antithrombotic compounds
antithrombotic
compounds
Prior art date
Application number
HK01104760A
Other languages
English (en)
Inventor
Basten Johannes Egbertus Maria
Boeckel Constant Adriaan Van Anton
Buijsman Rogier Christian
Dreef-Tromp Cornelia Maria
Original Assignee
Univ Leiden
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leiden, Organon Nv filed Critical Univ Leiden
Publication of HK1034266A1 publication Critical patent/HK1034266A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK01104760A 1998-06-17 2001-07-10 Antithrombotic compounds HK1034266A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98202037 1998-06-17
PCT/EP1999/004100 WO1999065934A1 (en) 1998-06-17 1999-06-11 Antithrombotic compounds

Publications (1)

Publication Number Publication Date
HK1034266A1 true HK1034266A1 (en) 2001-10-19

Family

ID=8233825

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01104760A HK1034266A1 (en) 1998-06-17 2001-07-10 Antithrombotic compounds

Country Status (31)

Country Link
US (1) US6486129B1 (zh)
EP (1) EP1087992B1 (zh)
JP (1) JP4369052B2 (zh)
KR (1) KR100790910B1 (zh)
CN (1) CN1261450C (zh)
AR (1) AR019674A1 (zh)
AT (1) ATE405580T1 (zh)
AU (1) AU756493B2 (zh)
BR (1) BR9911300A (zh)
CA (1) CA2334863C (zh)
CO (1) CO5080750A1 (zh)
CY (1) CY1108567T1 (zh)
CZ (1) CZ299382B6 (zh)
DE (1) DE69939378D1 (zh)
DK (1) DK1087992T3 (zh)
ES (1) ES2312210T3 (zh)
HK (1) HK1034266A1 (zh)
HU (1) HU229088B1 (zh)
ID (1) ID26614A (zh)
IL (2) IL139955A0 (zh)
NO (1) NO326057B1 (zh)
NZ (1) NZ508623A (zh)
PE (1) PE20000700A1 (zh)
PL (1) PL199433B1 (zh)
PT (1) PT1087992E (zh)
RU (1) RU2225869C2 (zh)
SK (1) SK286755B6 (zh)
TR (1) TR200003710T2 (zh)
TW (1) TWI221156B (zh)
WO (1) WO1999065934A1 (zh)
ZA (1) ZA200007075B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486129B1 (en) * 1998-06-17 2002-11-26 Akzo Nobel N.V. Antithrombotic compounds
TWI289566B (en) * 1999-12-07 2007-11-11 N.V.Organon Antithrombotic compound
DE10049937A1 (de) * 2000-10-06 2002-04-11 Knoll Ag Niedermolekulare Inhibitoren von Serinproteasen mit Polyhydroxyalkyl- und Polyhydroxycycloalkylresten
JP2005525325A (ja) * 2002-01-31 2005-08-25 モルフォケム アクチェンゲゼルシャフト フュア コンビナトリシェ ヘミー Xa因子活性を阻害する化合物
DE10300049A1 (de) * 2003-01-03 2004-07-15 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen, die Faktor VIIa inhibieren
DE10330900B4 (de) * 2003-07-01 2006-09-14 Leibniz-Institut Für Polymerforschung Dresden E.V. Biomaterial mit einem modularen Beschichtungssystem zur Anwendung in Medizinprodukten mit direktem Blutkontakt
EP1574516A1 (en) * 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
TW200621794A (en) * 2004-10-06 2006-07-01 Akzo Nobel Nv Pulmonary administration of an antithrombotic compound
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
US8183228B2 (en) * 2005-10-10 2012-05-22 MSD OSS B.V. Netherlands Anticoagulant antithrombotic dual inhibitors comprising a biotin label
EP1991272A2 (en) * 2005-10-10 2008-11-19 N.V. Organon Antithrombotic compound
WO2010037180A1 (en) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic oligosaccharide conjugates
JP2022538674A (ja) 2019-07-01 2022-09-05 トニックス ファーマ リミテッド 抗cd154抗体およびその使用
AU2022205313A1 (en) 2021-01-06 2023-07-20 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84170B (pt) * 1986-01-24 1989-03-30 Sanofi Sa Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas
DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
DE4206858A1 (de) 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
NZ264340A (en) * 1993-09-01 1995-04-27 Akzo Nobel Nv Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions
IL120722A (en) * 1996-05-08 1999-07-14 Akzo Nobel Nv Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them
US6486129B1 (en) * 1998-06-17 2002-11-26 Akzo Nobel N.V. Antithrombotic compounds

Also Published As

Publication number Publication date
NZ508623A (en) 2002-11-26
RU2225869C2 (ru) 2004-03-20
PE20000700A1 (es) 2000-08-14
ZA200007075B (en) 2002-02-28
EP1087992B1 (en) 2008-08-20
IL139955A (en) 2006-08-20
SK286755B6 (sk) 2009-05-07
TWI221156B (en) 2004-09-21
DK1087992T3 (da) 2008-11-24
CZ299382B6 (cs) 2008-07-09
CZ20004735A3 (cs) 2001-08-15
WO1999065934A1 (en) 1999-12-23
US6486129B1 (en) 2002-11-26
ES2312210T3 (es) 2009-02-16
NO326057B1 (no) 2008-09-08
JP4369052B2 (ja) 2009-11-18
NO20006317D0 (no) 2000-12-12
PL345238A1 (en) 2001-12-03
AU756493B2 (en) 2003-01-16
BR9911300A (pt) 2001-04-03
HUP0102764A3 (en) 2003-11-28
CA2334863C (en) 2011-02-15
KR20010052943A (ko) 2001-06-25
SK19222000A3 (sk) 2001-07-10
NO20006317L (no) 2001-02-14
AR019674A1 (es) 2002-03-13
ID26614A (id) 2001-01-25
CO5080750A1 (es) 2001-09-25
HU229088B1 (en) 2013-07-29
CN1261450C (zh) 2006-06-28
AU4512999A (en) 2000-01-05
IL139955A0 (en) 2002-02-10
CA2334863A1 (en) 1999-12-23
CY1108567T1 (el) 2014-04-09
PT1087992E (pt) 2008-10-17
EP1087992A1 (en) 2001-04-04
ATE405580T1 (de) 2008-09-15
HUP0102764A2 (hu) 2001-12-28
DE69939378D1 (de) 2008-10-02
CN1305494A (zh) 2001-07-25
JP2002518407A (ja) 2002-06-25
KR100790910B1 (ko) 2008-01-03
PL199433B1 (pl) 2008-09-30
TR200003710T2 (tr) 2001-04-20

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160611