HK1028238A1 - Benzo(5,6) cyclohepta(1,2B) pyridine derivatives useful for inhibition of farnesyl protein transferase. - Google Patents

Benzo(5,6) cyclohepta(1,2B) pyridine derivatives useful for inhibition of farnesyl protein transferase.

Info

Publication number
HK1028238A1
HK1028238A1 HK00106503A HK00106503A HK1028238A1 HK 1028238 A1 HK1028238 A1 HK 1028238A1 HK 00106503 A HK00106503 A HK 00106503A HK 00106503 A HK00106503 A HK 00106503A HK 1028238 A1 HK1028238 A1 HK 1028238A1
Authority
HK
Hong Kong
Prior art keywords
aryl
alkyl
aralkyl
heteroaryl
protein transferase
Prior art date
Application number
HK00106503A
Other languages
English (en)
Inventor
Arthur G Taveras
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of HK1028238A1 publication Critical patent/HK1028238A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK00106503A 1997-06-17 2000-10-12 Benzo(5,6) cyclohepta(1,2B) pyridine derivatives useful for inhibition of farnesyl protein transferase. HK1028238A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87767397A 1997-06-17 1997-06-17
PCT/US1998/011498 WO1998057962A1 (en) 1997-06-17 1998-06-15 Benzo(5,6)cyclohepta(1,2b)pyridine derivatives useful for inhibition of farnesyl protein transferase

Publications (1)

Publication Number Publication Date
HK1028238A1 true HK1028238A1 (en) 2001-02-09

Family

ID=25370476

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00106503A HK1028238A1 (en) 1997-06-17 2000-10-12 Benzo(5,6) cyclohepta(1,2B) pyridine derivatives useful for inhibition of farnesyl protein transferase.

Country Status (14)

Country Link
EP (1) EP0993460B1 (de)
JP (1) JP2002504147A (de)
KR (1) KR20010013828A (de)
CN (1) CN1172932C (de)
AT (1) ATE276247T1 (de)
AU (1) AU753533B2 (de)
CA (1) CA2293372C (de)
DE (1) DE69826281T2 (de)
ES (1) ES2226142T3 (de)
HK (1) HK1028238A1 (de)
HU (1) HUP0004806A3 (de)
IL (1) IL133390A0 (de)
NZ (1) NZ501615A (de)
WO (1) WO1998057962A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2005118407A (ru) * 2002-12-13 2006-03-10 СмитКлайн Бичем Корпорейшн (US) Производные пиперидина в качестве антагонистов ccr5
DE10334493B4 (de) * 2003-07-29 2006-01-05 Klingelnberg Gmbh Verfahren zum Fräsen von Spiralkegelrädern
EP3741745B1 (de) 2018-01-19 2023-04-26 Yuki Gosei Kogyo Co., Ltd. Verfahren zur herstellung eines n-alkoxycarbonylpiperidinderivats und zwischenprodukt dafür

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
WO1989010369A1 (en) * 1988-04-28 1989-11-02 Schering Corporation Novel benzopyrido piperidine, piperidylidene and piperazine compounds, compositions, methods of manufacture and methods of use
US5719148A (en) * 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them

Also Published As

Publication number Publication date
CN1267298A (zh) 2000-09-20
NZ501615A (en) 2002-02-01
AU7815398A (en) 1999-01-04
EP0993460A1 (de) 2000-04-19
DE69826281D1 (de) 2004-10-21
CA2293372C (en) 2009-01-13
WO1998057962A1 (en) 1998-12-23
JP2002504147A (ja) 2002-02-05
CN1172932C (zh) 2004-10-27
CA2293372A1 (en) 1998-12-23
DE69826281T2 (de) 2005-11-17
KR20010013828A (ko) 2001-02-26
HUP0004806A3 (en) 2002-11-28
ATE276247T1 (de) 2004-10-15
EP0993460B1 (de) 2004-09-15
AU753533B2 (en) 2002-10-17
HUP0004806A2 (hu) 2001-10-28
ES2226142T3 (es) 2005-03-16
IL133390A0 (en) 2001-04-30

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080615