HK1022833A1 - Pharmaceutical compositions comprising s-alkylisothiouronium derivatives - Google Patents

Pharmaceutical compositions comprising s-alkylisothiouronium derivatives

Info

Publication number
HK1022833A1
HK1022833A1 HK00101803A HK00101803A HK1022833A1 HK 1022833 A1 HK1022833 A1 HK 1022833A1 HK 00101803 A HK00101803 A HK 00101803A HK 00101803 A HK00101803 A HK 00101803A HK 1022833 A1 HK1022833 A1 HK 1022833A1
Authority
HK
Hong Kong
Prior art keywords
pct
pharmaceutical compositions
sec
processes
alkylisothiouronium
Prior art date
Application number
HK00101803A
Other languages
English (en)
Inventor
I Levi Mizrakh
I Victor Gikavy
V Valentin Znamensky
V Evgeni Arzamastsev
B Lev Shagalov
Valeri Kovtun
H Vladimir Jashounsky
V Victor Darchuk
G Marina Kochetkova
I Galina Bondareva
A Olga Terekhova
Original Assignee
Meditor Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU96119163A external-priority patent/RU2142796C1/ru
Priority claimed from RU97115433/14A external-priority patent/RU2187309C2/ru
Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd
Publication of HK1022833A1 publication Critical patent/HK1022833A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
HK00101803A 1996-09-26 2000-03-23 Pharmaceutical compositions comprising s-alkylisothiouronium derivatives HK1022833A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU96119163A RU2142796C1 (ru) 1996-09-26 1996-09-26 Лекарственное противошоковое средство
RU97115433/14A RU2187309C2 (ru) 1997-09-19 1997-09-19 Средство, влияющее на артериальное давление
PCT/IL1997/000314 WO1998013036A1 (en) 1996-09-26 1997-09-25 Pharmaceutical compositions comprising s-alkylisothiouronium derivatives

Publications (1)

Publication Number Publication Date
HK1022833A1 true HK1022833A1 (en) 2000-08-25

Family

ID=26653892

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00101803A HK1022833A1 (en) 1996-09-26 2000-03-23 Pharmaceutical compositions comprising s-alkylisothiouronium derivatives

Country Status (18)

Country Link
US (1) US6160008A (es)
EP (1) EP0928191B1 (es)
JP (1) JP4260888B2 (es)
KR (1) KR100575507B1 (es)
CN (1) CN1116871C (es)
AT (1) ATE222758T1 (es)
AU (1) AU717712B2 (es)
BR (1) BR9712851A (es)
CA (1) CA2266533C (es)
DE (1) DE69715013T2 (es)
DK (1) DK0928191T3 (es)
ES (1) ES2182116T3 (es)
HK (1) HK1022833A1 (es)
IL (1) IL129020A (es)
NO (1) NO326600B1 (es)
PT (1) PT928191E (es)
TR (1) TR199900783T2 (es)
WO (1) WO1998013036A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2296792T3 (es) * 2000-09-05 2008-05-01 Meditor Pharmaceuticals Ltd. Composiciones farmaceuticas para cefalea, ,migraña, nauseas y emesis.
JP2009507068A (ja) * 2005-09-06 2009-02-19 メディター ファーマスーティカルズ リミテッド 血液透析患者における低血圧予防及び血圧安定化
US20090186854A1 (en) * 2006-03-23 2009-07-23 Meditor Pharmaceuticals Ltd. S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
US20100285127A1 (en) * 2007-06-13 2010-11-11 Refael Barkan Taste masked pharmaceutical compositions of s-alkylisothiouronium derivatives
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
EP2219447B1 (en) * 2007-11-06 2013-07-03 Barkan-Farma S.r.l. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
MD3619G2 (ro) * 2007-11-06 2009-01-31 Рафаэль Баркан Remediu medicamentos nazal cu acţiune anticongestivă
CN104140386A (zh) * 2014-02-12 2014-11-12 上海应用技术学院 一种2-苄基-异硫脲三氟乙酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123636A (en) * 1964-03-03 Thiuronium h alii
US3116327A (en) * 1960-07-22 1963-12-31 Baxter Laboratories Inc Upsilon-dimethylaminopropyl isothiourea and acid addition salts thereof
US3657337A (en) * 1967-12-04 1972-04-18 Sandoz Ag Benzylideneamino guanidines
FR2419675A1 (fr) * 1978-03-16 1979-10-12 Philagro Sa Compositions fongicides a base de phosphites d'isothiouronium
AT395012B (de) * 1986-06-27 1992-08-25 Richter Gedeon Vegyeszet Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen

Also Published As

Publication number Publication date
CA2266533A1 (en) 1998-04-02
JP4260888B2 (ja) 2009-04-30
AU4317897A (en) 1998-04-17
DE69715013D1 (de) 2002-10-02
AU717712B2 (en) 2000-03-30
EP0928191B1 (en) 2002-08-28
ATE222758T1 (de) 2002-09-15
ES2182116T3 (es) 2003-03-01
KR20000048636A (ko) 2000-07-25
TR199900783T2 (xx) 1999-07-21
NO991419L (no) 1999-05-21
EP0928191A1 (en) 1999-07-14
CN1234737A (zh) 1999-11-10
US6160008A (en) 2000-12-12
DE69715013T2 (de) 2003-05-22
JP2001501928A (ja) 2001-02-13
NO326600B1 (no) 2009-01-19
IL129020A0 (en) 2000-02-17
PT928191E (pt) 2003-01-31
NO991419D0 (no) 1999-03-24
CN1116871C (zh) 2003-08-06
BR9712851A (pt) 2000-01-18
DK0928191T3 (da) 2002-12-30
KR100575507B1 (ko) 2006-05-03
WO1998013036A1 (en) 1998-04-02
CA2266533C (en) 2007-08-07
IL129020A (en) 2004-06-20

Similar Documents

Publication Publication Date Title
DE69506882D1 (de) Wasserlösliche organische salze von kreatin
SE9604793D0 (sv) New polymorphs
HUT73807A (en) 5-ht1-like indole derivatives and pharmaceutical compositions containing them
MX9702170A (es) Uso de inhibidores de la aromatasa para la produccion de un agente farmaceutico para el tratamiento de una deficiencia de androgeno relativa en los hombres.
TR199903331T2 (xx) Farnesil protein transferas engelleyicileri.
DE69819360D1 (de) Neue psoralene zur inaktivierung von pathogenen
DE69824433D1 (en) Proteintyrosinphosphatase inhibitoren
TR199900310T2 (xx) Trombin inhibit�rleri
DE59309183D1 (de) Simultane sequenzierung von nukleinsäuren
IL129020A0 (en) Pharmaceutical compositions comprising s-alkylisothiouronium derivatives
GB9126725D0 (en) Process
PL327335A1 (en) Preserving solution
IL152097A0 (en) Use of pyrazole derivatives for treating infertility
ATE232191T1 (de) Verfahren und zusammensetzung zur inhibierung der polymerisierung von ethylenisch ungesättigten kohlenwasserstoffen
IL142220A0 (en) Method of treating viral hemorrhagic fever
GB2324091A (en) Metalloproteinase inhibitors
DE59703451D1 (de) Verfahren zur reduktion von schwefel- und küpenfarbstoffen
DK0640098T3 (da) S-gen fra hundecoronavirus og anvendelser deraf
ES2089091T3 (es) Complejos que contienen acidos s(+)-fenilalcanoicos y acidos alfa-hidroalcanoicos.
ES2185154T3 (es) Metodo de uso de inhibidores de la ciclooxigenasa-2 en el tratamiento y prevencion de la demencia.
MY113423A (en) Substituted thiophenesulfonylureas and -thioureas processes for their preparation, their use as amedicament or diagnostic, and medicament contiaining them
GEP20022655B (en) Substituted Nitrogen Containing Heterocycles as Inhibitors of p38 Protein Kinase
UA22123C2 (uk) Hегорюча hеhьютоhівська мастильhа рідиhа

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110925