ATE222758T1 - S-alkylisothiouronium-derivate enthaltende pharmazeutische zusammensetzungen - Google Patents

S-alkylisothiouronium-derivate enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE222758T1
ATE222758T1 AT97941178T AT97941178T ATE222758T1 AT E222758 T1 ATE222758 T1 AT E222758T1 AT 97941178 T AT97941178 T AT 97941178T AT 97941178 T AT97941178 T AT 97941178T AT E222758 T1 ATE222758 T1 AT E222758T1
Authority
AT
Austria
Prior art keywords
pct
pharmaceutical compositions
compositions containing
sec
processes
Prior art date
Application number
AT97941178T
Other languages
English (en)
Inventor
I Lev Mizrakh
I Victor Gikavy
V Valentin Znamensky
V Evgeni Arzamastsev
B Lev Shagalov
Valeri Kovtun
H Vladimir Jashounsky
V Victor Darchuk
G Marina Kochetkova
I Galina Bondareva
A Olga Terekhova
Original Assignee
Meditor Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU96119163A external-priority patent/RU2142796C1/ru
Priority claimed from RU97115433/14A external-priority patent/RU2187309C2/ru
Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE222758T1 publication Critical patent/ATE222758T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT97941178T 1996-09-26 1997-09-25 S-alkylisothiouronium-derivate enthaltende pharmazeutische zusammensetzungen ATE222758T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU96119163A RU2142796C1 (ru) 1996-09-26 1996-09-26 Лекарственное противошоковое средство
RU97115433/14A RU2187309C2 (ru) 1997-09-19 1997-09-19 Средство, влияющее на артериальное давление
PCT/IL1997/000314 WO1998013036A1 (en) 1996-09-26 1997-09-25 Pharmaceutical compositions comprising s-alkylisothiouronium derivatives

Publications (1)

Publication Number Publication Date
ATE222758T1 true ATE222758T1 (de) 2002-09-15

Family

ID=26653892

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97941178T ATE222758T1 (de) 1996-09-26 1997-09-25 S-alkylisothiouronium-derivate enthaltende pharmazeutische zusammensetzungen

Country Status (18)

Country Link
US (1) US6160008A (de)
EP (1) EP0928191B1 (de)
JP (1) JP4260888B2 (de)
KR (1) KR100575507B1 (de)
CN (1) CN1116871C (de)
AT (1) ATE222758T1 (de)
AU (1) AU717712B2 (de)
BR (1) BR9712851A (de)
CA (1) CA2266533C (de)
DE (1) DE69715013T2 (de)
DK (1) DK0928191T3 (de)
ES (1) ES2182116T3 (de)
HK (1) HK1022833A1 (de)
IL (1) IL129020A (de)
NO (1) NO326600B1 (de)
PT (1) PT928191E (de)
TR (1) TR199900783T2 (de)
WO (1) WO1998013036A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100448439C (zh) * 2000-09-05 2009-01-07 麦迪特制药有限公司 用于头痛、偏头痛、恶心和呕吐的药物组合物
US20090018206A1 (en) * 2005-09-06 2009-01-15 Meditor Pharmaceuticals Ltd. Prevention of hypotension and stabilization of blood pressure in hemodialysis patients
US20090186854A1 (en) * 2006-03-23 2009-07-23 Meditor Pharmaceuticals Ltd. S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
EA200901591A1 (ru) * 2007-06-13 2010-06-30 Медитор Фармасьютикалс Лтд. Фармацевтические композиции производных s-алкилизотиоурония с маскированным вкусом
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
EA030035B1 (ru) * 2007-11-06 2018-06-29 Меламед, Лемуил Применение s-этилизотиоурония диэтилфосфата для изготовления лекарственного средства для лечения нарушения матки
MD3619G2 (ro) * 2007-11-06 2009-01-31 Рафаэль Баркан Remediu medicamentos nazal cu acţiune anticongestivă
CN104140386A (zh) * 2014-02-12 2014-11-12 上海应用技术学院 一种2-苄基-异硫脲三氟乙酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123636A (en) * 1964-03-03 Thiuronium h alii
US3116327A (en) * 1960-07-22 1963-12-31 Baxter Laboratories Inc Upsilon-dimethylaminopropyl isothiourea and acid addition salts thereof
US3657337A (en) * 1967-12-04 1972-04-18 Sandoz Ag Benzylideneamino guanidines
FR2419675A1 (fr) * 1978-03-16 1979-10-12 Philagro Sa Compositions fongicides a base de phosphites d'isothiouronium
AT395012B (de) * 1986-06-27 1992-08-25 Richter Gedeon Vegyeszet Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen

Also Published As

Publication number Publication date
PT928191E (pt) 2003-01-31
IL129020A (en) 2004-06-20
ES2182116T3 (es) 2003-03-01
EP0928191B1 (de) 2002-08-28
CN1116871C (zh) 2003-08-06
US6160008A (en) 2000-12-12
NO991419D0 (no) 1999-03-24
AU717712B2 (en) 2000-03-30
DK0928191T3 (da) 2002-12-30
NO326600B1 (no) 2009-01-19
TR199900783T2 (xx) 1999-07-21
BR9712851A (pt) 2000-01-18
IL129020A0 (en) 2000-02-17
AU4317897A (en) 1998-04-17
DE69715013T2 (de) 2003-05-22
DE69715013D1 (de) 2002-10-02
CA2266533A1 (en) 1998-04-02
WO1998013036A1 (en) 1998-04-02
CA2266533C (en) 2007-08-07
KR20000048636A (ko) 2000-07-25
EP0928191A1 (de) 1999-07-14
NO991419L (no) 1999-05-21
JP2001501928A (ja) 2001-02-13
HK1022833A1 (en) 2000-08-25
CN1234737A (zh) 1999-11-10
KR100575507B1 (ko) 2006-05-03
JP4260888B2 (ja) 2009-04-30

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