HK1018779A1 - Novel substituted (2(1-piperazinyl)ethoxy) methyl - Google Patents

Novel substituted (2(1-piperazinyl)ethoxy) methyl

Info

Publication number
HK1018779A1
HK1018779A1 HK99103797A HK99103797A HK1018779A1 HK 1018779 A1 HK1018779 A1 HK 1018779A1 HK 99103797 A HK99103797 A HK 99103797A HK 99103797 A HK99103797 A HK 99103797A HK 1018779 A1 HK1018779 A1 HK 1018779A1
Authority
HK
Hong Kong
Prior art keywords
piperazinyl
ethoxy
methyl
novel substituted
substituted
Prior art date
Application number
HK99103797A
Other languages
English (en)
Inventor
Guy Duchene
Michel Deleers
Guy Bodson
Genevieve Motte
Francoise Lurquin
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of HK1018779A1 publication Critical patent/HK1018779A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK99103797A 1996-04-10 1999-09-02 Novel substituted (2(1-piperazinyl)ethoxy) methyl HK1018779A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE9600310A BE1010094A3 (fr) 1996-04-10 1996-04-10 Nouveaux [2-(1-piperazinyl)ethoxy] methyle substitues.
PCT/BE1997/000038 WO1997037982A1 (fr) 1996-04-10 1997-03-28 Nouveaux [2-(1-piperazinyl)ethoxy]methyle substitues

Publications (1)

Publication Number Publication Date
HK1018779A1 true HK1018779A1 (en) 2000-01-07

Family

ID=3889663

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99103797A HK1018779A1 (en) 1996-04-10 1999-09-02 Novel substituted (2(1-piperazinyl)ethoxy) methyl

Country Status (26)

Country Link
US (2) US6140501A (ru)
EP (1) EP0927173B1 (ru)
JP (1) JP2000508634A (ru)
CN (1) CN1072661C (ru)
AR (1) AR006761A1 (ru)
AT (1) ATE219067T1 (ru)
AU (1) AU710835B2 (ru)
BE (1) BE1010094A3 (ru)
BR (1) BR9708763A (ru)
CZ (1) CZ295068B6 (ru)
DE (1) DE69713352T2 (ru)
DK (1) DK0927173T3 (ru)
EA (1) EA000831B1 (ru)
ES (1) ES2177965T3 (ru)
HK (1) HK1018779A1 (ru)
HU (1) HU225478B1 (ru)
IN (1) IN186873B (ru)
MY (1) MY118237A (ru)
NO (1) NO311615B1 (ru)
NZ (1) NZ332057A (ru)
PL (1) PL188819B1 (ru)
PT (1) PT927173E (ru)
RS (1) RS49574B (ru)
TR (1) TR199802025T2 (ru)
WO (1) WO1997037982A1 (ru)
ZA (1) ZA972973B (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0919550A1 (en) * 1997-11-26 1999-06-02 Ucb, S.A. Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride
IL124195A (en) * 1998-04-23 2000-08-31 Chemagis Ltd Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid
EP1233954B1 (en) * 1999-11-30 2004-10-20 Egis Gyogyszergyar Rt. A process for the preparation of 2- 4-(alpha-phenyl-p-chlorobenzyl)piperazin-1-yl]ethoxy acetic acid and novel intermediates therefor
US7199241B1 (en) 2001-05-29 2007-04-03 Ucb, S.A. Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US6977301B1 (en) 2001-05-29 2005-12-20 Ucb, S.A. Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US6838052B2 (en) 2001-06-29 2005-01-04 Symyx Technologies, Inc. In-situ injection and materials screening device
JP2005503368A (ja) * 2001-07-26 2005-02-03 ユ セ ベ ソシエテ アノニム 2−(2−(4−(ビス(4−フルオロフェニル)メチル)−ピペラジン−1−イル)エトキシ)酢酸誘導体、又は対応するその塩形態及びそのための中間体の調製方法
US7160513B2 (en) 2002-12-20 2007-01-09 Symyx Technologies, Inc. Batch reactor with injection system
US20040266787A1 (en) * 2003-03-25 2004-12-30 Dr. Reddy's Laboratories Limited Novel amorphous form of [2-[4-[(4-chlorophenyl)-phenyl methyl]-1-piperazinyl]ethoxy]acetic acid and process for the preparation thereof
US20050020608A1 (en) * 2003-03-25 2005-01-27 Dr. Reddy's Laboratories Limited Crystalline cetirizine monohydrochloride
WO2004103982A1 (en) * 2003-05-21 2004-12-02 Wockhardt Limited 2-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl]ethoxy]acetic acid monohydrochloride as anti-allergenic compound and process for its production
KR100503443B1 (ko) * 2004-02-02 2005-07-22 한림제약(주) 광학적으로 활성인 세티리진 또는 그의 염의 제조방법
WO2006050909A1 (en) * 2004-11-10 2006-05-18 Ucb Farchim Sa Novel forms of efletirizine dihydrochloride, processes for making them and pharmaceutical compositions including them
EP1845088B1 (en) * 2006-04-10 2009-07-22 Ranbaxy Laboratories Limited An improved process for the preparation of aripipirazole
US20110172425A1 (en) * 2008-09-17 2011-07-14 Calyx Chemicals And Pharmaceuticals Pvt. Ltd. Novel water based process for the preparation of substituted diphenylmethyl piperazines
KR101418404B1 (ko) 2012-01-06 2014-07-10 한미약품 주식회사 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 함유하는 안정한 경구투여용 약학 제제
KR102226833B1 (ko) 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH505116A (it) * 1966-11-21 1971-03-31 Crc Ricerca Chim Metodo per l'ottenimento di derivati della piperazina
GB1184395A (en) * 1967-03-08 1970-03-18 Egyt Gyogyszervegyeszeti Gyar Substituted Piperazine Derivatives
NO155805C (no) * 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.
GB8827390D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride
GB8827391D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride

Also Published As

Publication number Publication date
PT927173E (pt) 2002-11-29
EA199800879A1 (ru) 1999-02-25
PL329307A1 (en) 1999-03-15
AU2281897A (en) 1997-10-29
DE69713352T2 (de) 2003-02-20
DK0927173T3 (da) 2002-09-16
NO311615B1 (no) 2001-12-17
CZ315198A3 (cs) 1999-03-17
CZ295068B6 (cs) 2005-05-18
MY118237A (en) 2004-09-30
EP0927173A1 (fr) 1999-07-07
IN186873B (ru) 2001-12-01
WO1997037982A1 (fr) 1997-10-16
CN1072661C (zh) 2001-10-10
AU710835B2 (en) 1999-09-30
RS49574B (sr) 2007-04-10
BE1010094A3 (fr) 1997-12-02
ATE219067T1 (de) 2002-06-15
HUP9901804A2 (hu) 1999-09-28
CN1215395A (zh) 1999-04-28
NO984738L (no) 1998-12-08
US6255487B1 (en) 2001-07-03
NZ332057A (en) 2000-03-27
JP2000508634A (ja) 2000-07-11
HUP9901804A3 (en) 2000-06-28
EA000831B1 (ru) 2000-04-24
YU44198A (sh) 1999-07-28
TR199802025T2 (xx) 1999-01-18
BR9708763A (pt) 1999-08-03
ZA972973B (en) 1997-11-03
AR006761A1 (es) 1999-09-29
NO984738D0 (no) 1998-10-09
US6140501A (en) 2000-10-31
HU225478B1 (en) 2006-12-28
PL188819B1 (pl) 2005-04-29
EP0927173B1 (fr) 2002-06-12
DE69713352D1 (en) 2002-07-18
ES2177965T3 (es) 2002-12-16

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090328