HK1014929A1 - Tetralines - Google Patents
TetralinesInfo
- Publication number
- HK1014929A1 HK1014929A1 HK98112165A HK98112165A HK1014929A1 HK 1014929 A1 HK1014929 A1 HK 1014929A1 HK 98112165 A HK98112165 A HK 98112165A HK 98112165 A HK98112165 A HK 98112165A HK 1014929 A1 HK1014929 A1 HK 1014929A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tetralines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
- C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9509156.7A GB9509156D0 (en) | 1995-05-05 | 1995-05-05 | Organic compounds |
| PCT/EP1996/001841 WO1996034849A1 (en) | 1995-05-05 | 1996-05-03 | Tetralines bearing a phenyl substituant on the aromatic ring and their use in the treatment of epilepsy, stroke and brain or spinal trauma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1014929A1 true HK1014929A1 (en) | 1999-10-08 |
Family
ID=10774032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK98112165A HK1014929A1 (en) | 1995-05-05 | 1998-11-20 | Tetralines |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6169116B1 (pt) |
| EP (1) | EP0823892B1 (pt) |
| JP (1) | JP3194965B2 (pt) |
| KR (1) | KR100435009B1 (pt) |
| CN (1) | CN1122019C (pt) |
| AR (1) | AR004484A1 (pt) |
| AT (1) | ATE193884T1 (pt) |
| AU (1) | AU706392B2 (pt) |
| BR (1) | BR9608169A (pt) |
| CA (1) | CA2217855C (pt) |
| CO (1) | CO4440486A1 (pt) |
| CZ (1) | CZ292022B6 (pt) |
| DE (1) | DE69608891T2 (pt) |
| DK (1) | DK0823892T3 (pt) |
| ES (1) | ES2148772T3 (pt) |
| FI (1) | FI973530A (pt) |
| GB (1) | GB9509156D0 (pt) |
| GR (1) | GR3033715T3 (pt) |
| HK (1) | HK1014929A1 (pt) |
| HU (1) | HUP9801068A3 (pt) |
| IL (1) | IL118141A (pt) |
| MX (1) | MX9708510A (pt) |
| NO (1) | NO308948B1 (pt) |
| NZ (1) | NZ308471A (pt) |
| PE (1) | PE54797A1 (pt) |
| PL (1) | PL182857B1 (pt) |
| PT (1) | PT823892E (pt) |
| RU (1) | RU2169727C2 (pt) |
| SK (1) | SK282022B6 (pt) |
| TR (1) | TR199701298T1 (pt) |
| TW (1) | TW359667B (pt) |
| WO (1) | WO1996034849A1 (pt) |
| ZA (1) | ZA963540B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1458386T1 (sl) | 2001-12-27 | 2007-08-31 | Ortho Mcneil Pharm Inc | Aroil pirol heteroeril in metanoli, uporabni za zdravljenje motnje centralnega živčnega sistema |
| AU2003241453A1 (en) * | 2002-05-17 | 2003-12-02 | Janssen Pharmaceutica N.V. | Aminotetralin-derived urea modulators of vanilloid vr1 receptor |
| WO2005037286A1 (en) | 2003-03-25 | 2005-04-28 | Vasopharm Biotech Gmbh | Use of pteridine derivatives for the treatment of increased intracranial pressure and secondary ischemia |
| EP1956006A1 (en) * | 2007-02-06 | 2008-08-13 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted-tetrahydro-naphthalen derivatives as 5-HT7 receptor ligands |
| EP1975161A1 (en) * | 2007-03-28 | 2008-10-01 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted- tetrahydro-napthalen-amine derivatives, their preparation and use as medicaments |
| US20100227934A1 (en) * | 2007-06-15 | 2010-09-09 | University Of Florida Research Foundation, Inc | Therapeutic compounds and methods of use |
| EP2011786A1 (en) * | 2007-07-05 | 2009-01-07 | Laboratorios del Dr. Esteve S.A. | Indane-amine derivatives, their preparation and use as medicaments |
| EP3145906B1 (en) * | 2014-05-19 | 2023-10-04 | Northeastern University | Serotonin receptor-targeting compounds |
| EP4200287A2 (en) * | 2020-08-19 | 2023-06-28 | Northeastern University | Serotonin receptor modulators |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6045179B2 (ja) * | 1977-06-08 | 1985-10-08 | フナイ薬品工業株式会社 | 新規環状アミノアルコ−ル類およびその製造法 |
| EP0257285A3 (en) | 1986-07-28 | 1989-12-27 | Whitby Research Incorporated | Method and compositions for reducing the intraocular pressure of mammals |
| DE3718317A1 (de) | 1986-12-10 | 1988-06-16 | Bayer Ag | Substituierte basische 2-aminotetraline |
| EP0381902A1 (en) | 1989-01-09 | 1990-08-16 | Merrell Dow Pharmaceuticals Inc. | Tetralin derivatives |
| JP2931986B2 (ja) | 1989-02-17 | 1999-08-09 | 武田薬品工業株式会社 | アラルキルアミン誘導体 |
| SE8901889D0 (sv) | 1989-05-26 | 1989-05-26 | Astra Ab | Novel 8-substituted-2-aminotetralines |
| ATE185813T1 (de) | 1993-08-27 | 1999-11-15 | Hoffmann La Roche | Tetrahydronaphthalin-peptidderivate |
| FR2711139B1 (fr) * | 1993-10-15 | 1995-12-01 | Adir | Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1995
- 1995-05-05 GB GBGB9509156.7A patent/GB9509156D0/en active Pending
-
1996
- 1996-05-02 CO CO96021819A patent/CO4440486A1/es unknown
- 1996-05-03 DK DK96919659T patent/DK0823892T3/da active
- 1996-05-03 IL IL11814196A patent/IL118141A/en not_active IP Right Cessation
- 1996-05-03 PE PE1996000309A patent/PE54797A1/es not_active Application Discontinuation
- 1996-05-03 RU RU97119872/04A patent/RU2169727C2/ru not_active IP Right Cessation
- 1996-05-03 HU HU9801068A patent/HUP9801068A3/hu unknown
- 1996-05-03 NZ NZ308471A patent/NZ308471A/xx unknown
- 1996-05-03 SK SK1485-97A patent/SK282022B6/sk unknown
- 1996-05-03 CA CA002217855A patent/CA2217855C/en not_active Expired - Fee Related
- 1996-05-03 PT PT96919659T patent/PT823892E/pt unknown
- 1996-05-03 TW TW085105300A patent/TW359667B/zh active
- 1996-05-03 BR BR9608169A patent/BR9608169A/pt not_active IP Right Cessation
- 1996-05-03 ZA ZA9603540A patent/ZA963540B/xx unknown
- 1996-05-03 AT AT96919659T patent/ATE193884T1/de not_active IP Right Cessation
- 1996-05-03 MX MX9708510A patent/MX9708510A/es not_active IP Right Cessation
- 1996-05-03 ES ES96919659T patent/ES2148772T3/es not_active Expired - Lifetime
- 1996-05-03 WO PCT/EP1996/001841 patent/WO1996034849A1/en active IP Right Grant
- 1996-05-03 AR ARP960102447A patent/AR004484A1/es unknown
- 1996-05-03 CN CN96193739A patent/CN1122019C/zh not_active Expired - Fee Related
- 1996-05-03 AU AU58129/96A patent/AU706392B2/en not_active Ceased
- 1996-05-03 DE DE69608891T patent/DE69608891T2/de not_active Expired - Lifetime
- 1996-05-03 PL PL96323037A patent/PL182857B1/pl not_active IP Right Cessation
- 1996-05-03 EP EP96919659A patent/EP0823892B1/en not_active Expired - Lifetime
- 1996-05-03 TR TR97/01298T patent/TR199701298T1/xx unknown
- 1996-05-03 JP JP53301096A patent/JP3194965B2/ja not_active Expired - Fee Related
- 1996-05-03 KR KR1019970707827A patent/KR100435009B1/ko not_active IP Right Cessation
- 1996-05-03 CZ CZ19973486A patent/CZ292022B6/cs not_active IP Right Cessation
-
1997
- 1997-08-27 FI FI973530A patent/FI973530A/fi not_active IP Right Cessation
- 1997-11-04 NO NO975087A patent/NO308948B1/no unknown
-
1998
- 1998-11-20 HK HK98112165A patent/HK1014929A1/xx not_active IP Right Cessation
-
1999
- 1999-06-28 US US09/340,818 patent/US6169116B1/en not_active Expired - Fee Related
-
2000
- 2000-06-16 GR GR20000401405T patent/GR3033715T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20080503 |