HK1012347A1 - Condensed indole derivatives as 5-ht 4-receptor antagonists - Google Patents
Condensed indole derivatives as 5-ht 4-receptor antagonistsInfo
- Publication number
- HK1012347A1 HK1012347A1 HK98113455A HK98113455A HK1012347A1 HK 1012347 A1 HK1012347 A1 HK 1012347A1 HK 98113455 A HK98113455 A HK 98113455A HK 98113455 A HK98113455 A HK 98113455A HK 1012347 A1 HK1012347 A1 HK 1012347A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- alkyl
- hydrogen
- receptor antagonists
- indole derivatives
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939316195A GB9316195D0 (en) | 1993-08-05 | 1993-08-05 | Pharmaceuticals |
| PCT/EP1994/002514 WO1995004737A1 (en) | 1993-08-05 | 1994-07-28 | Condensed indole derivatives as 5-ht4-receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1012347A1 true HK1012347A1 (en) | 1999-07-30 |
Family
ID=10739981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK98113455A HK1012347A1 (en) | 1993-08-05 | 1998-12-15 | Condensed indole derivatives as 5-ht 4-receptor antagonists |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0712406B1 (xx) |
| JP (1) | JPH09502168A (xx) |
| CN (1) | CN1131949A (xx) |
| AT (1) | ATE172732T1 (xx) |
| AU (1) | AU695034B2 (xx) |
| CA (1) | CA2168750A1 (xx) |
| DE (1) | DE69414255T2 (xx) |
| DK (1) | DK0712406T3 (xx) |
| ES (1) | ES2125481T3 (xx) |
| GB (1) | GB9316195D0 (xx) |
| HK (1) | HK1012347A1 (xx) |
| NZ (1) | NZ271972A (xx) |
| WO (1) | WO1995004737A1 (xx) |
| ZA (1) | ZA945773B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
| JPH08502283A (ja) * | 1992-10-16 | 1996-03-12 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５−ｈｔ▲下４▼レセプターアンタゴニスト用の縮合環系ｎ−アルキルピペリジニル−４−メチルカルボン酸エステル／アミド |
| ATE250931T1 (de) * | 1996-02-15 | 2003-10-15 | Janssen Pharmaceutica Nv | Verwendung von 5-ht4 antagonisten zur überwindung der gastrointestinalen beschädigung, die durch inhibitoren der serotonin-wiederaufnahme hervorgerufen werden |
| GB9820294D0 (en) * | 1998-09-17 | 1998-11-11 | Smithkline Beecham Plc | Pharmaceuticals |
| US7608626B2 (en) | 2004-11-01 | 2009-10-27 | Wyeth | Substituted indolizines and derivatives as CNS agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60142981A (ja) * | 1983-12-28 | 1985-07-29 | Yoshitomi Pharmaceut Ind Ltd | ３−インド−ルカルボキサミド誘導体 |
| AP401A (en) * | 1992-03-12 | 1995-08-29 | Smithkline Beecham Plc | Condensed indole derivatives as 5H4-receptor antagonists. |
-
1993
- 1993-08-05 GB GB939316195A patent/GB9316195D0/en active Pending
-
1994
- 1994-07-28 CN CN94193556A patent/CN1131949A/zh active Pending
- 1994-07-28 EP EP94926128A patent/EP0712406B1/en not_active Expired - Lifetime
- 1994-07-28 ES ES94926128T patent/ES2125481T3/es not_active Expired - Lifetime
- 1994-07-28 AU AU76098/94A patent/AU695034B2/en not_active Ceased
- 1994-07-28 CA CA002168750A patent/CA2168750A1/en not_active Abandoned
- 1994-07-28 DK DK94926128T patent/DK0712406T3/da active
- 1994-07-28 NZ NZ271972A patent/NZ271972A/en unknown
- 1994-07-28 DE DE69414255T patent/DE69414255T2/de not_active Expired - Fee Related
- 1994-07-28 AT AT94926128T patent/ATE172732T1/de not_active IP Right Cessation
- 1994-07-28 WO PCT/EP1994/002514 patent/WO1995004737A1/en active IP Right Grant
- 1994-07-28 JP JP7506201A patent/JPH09502168A/ja active Pending
- 1994-08-03 ZA ZA945773A patent/ZA945773B/xx unknown
-
1998
- 1998-12-15 HK HK98113455A patent/HK1012347A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7609894A (en) | 1995-02-28 |
| WO1995004737A1 (en) | 1995-02-16 |
| JPH09502168A (ja) | 1997-03-04 |
| ATE172732T1 (de) | 1998-11-15 |
| DE69414255T2 (de) | 1999-05-12 |
| AU695034B2 (en) | 1998-08-06 |
| EP0712406B1 (en) | 1998-10-28 |
| CA2168750A1 (en) | 1995-02-16 |
| DK0712406T3 (da) | 1999-07-05 |
| ZA945773B (en) | 1996-02-05 |
| CN1131949A (zh) | 1996-09-25 |
| DE69414255D1 (de) | 1998-12-03 |
| NZ271972A (en) | 1997-07-27 |
| EP0712406A1 (en) | 1996-05-22 |
| ES2125481T3 (es) | 1999-03-01 |
| GB9316195D0 (en) | 1993-09-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |