ATE172732T1 - Kondensierte indol-derivate als 5-ht4-rezeptor- antagonisten - Google Patents
Kondensierte indol-derivate als 5-ht4-rezeptor- antagonistenInfo
- Publication number
- ATE172732T1 ATE172732T1 AT94926128T AT94926128T ATE172732T1 AT E172732 T1 ATE172732 T1 AT E172732T1 AT 94926128 T AT94926128 T AT 94926128T AT 94926128 T AT94926128 T AT 94926128T AT E172732 T1 ATE172732 T1 AT E172732T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- hydrogen
- receptor antagonists
- indole derivatives
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939316195A GB9316195D0 (en) | 1993-08-05 | 1993-08-05 | Pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE172732T1 true ATE172732T1 (de) | 1998-11-15 |
Family
ID=10739981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94926128T ATE172732T1 (de) | 1993-08-05 | 1994-07-28 | Kondensierte indol-derivate als 5-ht4-rezeptor- antagonisten |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0712406B1 (de) |
| JP (1) | JPH09502168A (de) |
| CN (1) | CN1131949A (de) |
| AT (1) | ATE172732T1 (de) |
| AU (1) | AU695034B2 (de) |
| CA (1) | CA2168750A1 (de) |
| DE (1) | DE69414255T2 (de) |
| DK (1) | DK0712406T3 (de) |
| ES (1) | ES2125481T3 (de) |
| GB (1) | GB9316195D0 (de) |
| HK (1) | HK1012347A1 (de) |
| NZ (1) | NZ271972A (de) |
| WO (1) | WO1995004737A1 (de) |
| ZA (1) | ZA945773B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
| WO1994008965A1 (en) * | 1992-10-16 | 1994-04-28 | Smithkline Beecham Plc | N-alkylpiperidinyl-4-methyl carboxylic esters/amides of condensed ring systems as 5-ht4 receptor antagonists |
| AU1767997A (en) * | 1996-02-15 | 1997-09-02 | Janssen Pharmaceutica N.V. | Use of 5ht4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors |
| GB9820294D0 (en) * | 1998-09-17 | 1998-11-11 | Smithkline Beecham Plc | Pharmaceuticals |
| CA2585967A1 (en) | 2004-11-01 | 2006-05-11 | Wyeth | Substituted indolizines and derivatives as cns agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60142981A (ja) * | 1983-12-28 | 1985-07-29 | Yoshitomi Pharmaceut Ind Ltd | ３−インド−ルカルボキサミド誘導体 |
| DE69325167T2 (de) * | 1992-03-12 | 2000-01-20 | Smithkline Beecham P.L.C., Brentford | Kondensierte indol-derivate als 5-ht4-rezeptor-antagonisten |
-
1993
- 1993-08-05 GB GB939316195A patent/GB9316195D0/en active Pending
-
1994
- 1994-07-28 WO PCT/EP1994/002514 patent/WO1995004737A1/en active IP Right Grant
- 1994-07-28 NZ NZ271972A patent/NZ271972A/en unknown
- 1994-07-28 JP JP7506201A patent/JPH09502168A/ja active Pending
- 1994-07-28 EP EP94926128A patent/EP0712406B1/de not_active Expired - Lifetime
- 1994-07-28 DK DK94926128T patent/DK0712406T3/da active
- 1994-07-28 CA CA002168750A patent/CA2168750A1/en not_active Abandoned
- 1994-07-28 ES ES94926128T patent/ES2125481T3/es not_active Expired - Lifetime
- 1994-07-28 CN CN94193556A patent/CN1131949A/zh active Pending
- 1994-07-28 AU AU76098/94A patent/AU695034B2/en not_active Ceased
- 1994-07-28 DE DE69414255T patent/DE69414255T2/de not_active Expired - Fee Related
- 1994-07-28 AT AT94926128T patent/ATE172732T1/de not_active IP Right Cessation
- 1994-08-03 ZA ZA945773A patent/ZA945773B/xx unknown
-
1998
- 1998-12-15 HK HK98113455A patent/HK1012347A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7609894A (en) | 1995-02-28 |
| ZA945773B (en) | 1996-02-05 |
| CN1131949A (zh) | 1996-09-25 |
| DE69414255T2 (de) | 1999-05-12 |
| JPH09502168A (ja) | 1997-03-04 |
| CA2168750A1 (en) | 1995-02-16 |
| HK1012347A1 (en) | 1999-07-30 |
| GB9316195D0 (en) | 1993-09-22 |
| AU695034B2 (en) | 1998-08-06 |
| EP0712406A1 (de) | 1996-05-22 |
| DE69414255D1 (de) | 1998-12-03 |
| NZ271972A (en) | 1997-07-27 |
| DK0712406T3 (da) | 1999-07-05 |
| EP0712406B1 (de) | 1998-10-28 |
| ES2125481T3 (es) | 1999-03-01 |
| WO1995004737A1 (en) | 1995-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |