HK1011537A1 - 10-Deacetyl-14beta-hydroxybaccatine iii derivatives a process for the preparation thereof and formulations containing them - Google Patents

10-Deacetyl-14beta-hydroxybaccatine iii derivatives a process for the preparation thereof and formulations containing them

Info

Publication number
HK1011537A1
HK1011537A1 HK98112700A HK98112700A HK1011537A1 HK 1011537 A1 HK1011537 A1 HK 1011537A1 HK 98112700 A HK98112700 A HK 98112700A HK 98112700 A HK98112700 A HK 98112700A HK 1011537 A1 HK1011537 A1 HK 1011537A1
Authority
HK
Hong Kong
Prior art keywords
pct
deacetyl
derivatives
14beta
preparation
Prior art date
Application number
HK98112700A
Other languages
English (en)
Inventor
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of HK1011537A1 publication Critical patent/HK1011537A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK98112700A 1995-05-19 1998-12-02 10-Deacetyl-14beta-hydroxybaccatine iii derivatives a process for the preparation thereof and formulations containing them HK1011537A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI951022A IT1275435B (it) 1995-05-19 1995-05-19 Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
PCT/EP1996/001919 WO1996036622A1 (en) 1995-05-19 1996-05-08 10-deacetyl-14beta-hydroxybaccatine iii derivatives, a process for the preparation thereof and formulations containing them

Publications (1)

Publication Number Publication Date
HK1011537A1 true HK1011537A1 (en) 1999-07-16

Family

ID=11371633

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98112700A HK1011537A1 (en) 1995-05-19 1998-12-02 10-Deacetyl-14beta-hydroxybaccatine iii derivatives a process for the preparation thereof and formulations containing them

Country Status (18)

Country Link
US (1) US5917056A (ja)
EP (1) EP0862563B1 (ja)
JP (1) JP4112001B2 (ja)
KR (1) KR100399330B1 (ja)
CN (1) CN100335469C (ja)
AT (1) ATE195312T1 (ja)
AU (1) AU696366B2 (ja)
CA (1) CA2212357C (ja)
DE (1) DE69609723T2 (ja)
DK (1) DK0862563T3 (ja)
ES (1) ES2148766T3 (ja)
GR (1) GR3034321T3 (ja)
HK (1) HK1011537A1 (ja)
IT (1) IT1275435B (ja)
NO (1) NO316378B1 (ja)
PT (1) PT862563E (ja)
RU (1) RU2161615C2 (ja)
WO (1) WO1996036622A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283633B1 (it) * 1996-05-10 1998-04-23 Indena Spa Derivati tassanici loro sintesi e formulazioni che li contengono
US5917062A (en) * 1997-11-21 1999-06-29 Indena S.P.A Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
IT1318678B1 (it) 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.
IT1320107B1 (it) 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
KR101009467B1 (ko) * 2006-03-13 2011-01-19 주식회사 셀트리온화학연구소 도세탁셀의 합성에 유용한 탁산 유도체 및 그 제조방법
CN101896474B (zh) * 2007-10-09 2016-02-03 希凯迪斯股份有限公司 制备缩酮和乙缩醛的方法
EP2080764B1 (en) 2008-01-18 2012-08-22 INDENA S.p.A. Solid forms of ortataxel
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254517B (it) * 1992-03-06 1995-09-25 Indena Spa 14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment

Also Published As

Publication number Publication date
ES2148766T3 (es) 2000-10-16
DK0862563T3 (da) 2000-10-30
NO316378B1 (no) 2004-01-19
US5917056A (en) 1999-06-29
CN1177961A (zh) 1998-04-01
IT1275435B (it) 1997-08-07
ITMI951022A0 (it) 1995-05-19
KR19980702749A (ko) 1998-08-05
AU5893996A (en) 1996-11-29
PT862563E (pt) 2000-11-30
DE69609723T2 (de) 2000-12-14
JPH11505232A (ja) 1999-05-18
CA2212357A1 (en) 1996-11-21
NO973545D0 (no) 1997-08-01
CN100335469C (zh) 2007-09-05
JP4112001B2 (ja) 2008-07-02
KR100399330B1 (ko) 2003-12-31
GR3034321T3 (en) 2000-12-29
CA2212357C (en) 2002-08-13
RU2161615C2 (ru) 2001-01-10
DE69609723D1 (de) 2000-09-14
ITMI951022A1 (it) 1996-11-19
ATE195312T1 (de) 2000-08-15
WO1996036622A1 (en) 1996-11-21
EP0862563B1 (en) 2000-08-09
NO973545L (no) 1997-11-17
EP0862563A1 (en) 1998-09-09
AU696366B2 (en) 1998-09-10

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150508