HK1009941A1 - Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers - Google Patents
Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockersInfo
- Publication number
- HK1009941A1 HK1009941A1 HK98110893A HK98110893A HK1009941A1 HK 1009941 A1 HK1009941 A1 HK 1009941A1 HK 98110893 A HK98110893 A HK 98110893A HK 98110893 A HK98110893 A HK 98110893A HK 1009941 A1 HK1009941 A1 HK 1009941A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- beta
- carbonic anhydrase
- blockers
- anhydrase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83986992A | 1992-02-21 | 1992-02-21 | |
PCT/US1993/001487 WO1993016701A2 (fr) | 1992-02-21 | 1993-02-19 | Compositions antiglaucome a usage local comprenant des inhibiteurs d'anhydrase carbonique et de beta-bloquants |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1009941A1 true HK1009941A1 (en) | 1999-06-11 |
Family
ID=25280847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK98110893A HK1009941A1 (en) | 1992-02-21 | 1998-09-24 | Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0625903B1 (fr) |
JP (2) | JP2965267B2 (fr) |
AT (1) | ATE169499T1 (fr) |
AU (1) | AU677577B2 (fr) |
CA (1) | CA2129037C (fr) |
DE (1) | DE69320329T2 (fr) |
DK (1) | DK0625903T3 (fr) |
ES (1) | ES2118941T3 (fr) |
HK (1) | HK1009941A1 (fr) |
WO (1) | WO1993016701A2 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG84487A1 (en) | 1991-04-17 | 2001-11-20 | Merck & Co Inc | Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a b-adrenergic antagonist |
US6316443B1 (en) | 1994-08-04 | 2001-11-13 | Merck & Co., Inc. | Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a β-adrenergic antagonist |
US6071904A (en) * | 1996-12-11 | 2000-06-06 | Alcon Laboratories, Inc. | Process for manufacturing ophthalmic suspensions |
CA2294343A1 (fr) * | 1997-06-26 | 1999-01-07 | Merck & Co., Inc. | Procede permettant d'optimiser l'etat de sante de la retine et du nerf optique |
WO1999037292A2 (fr) * | 1998-01-23 | 1999-07-29 | Merck Sharp & Dohme B.V. | Technique visant a accroitre la tension en oxygene du nerf optique et de la retine |
US6291506B1 (en) | 1998-08-04 | 2001-09-18 | Wisconsin Alumni Research Foundation | Method of reducing retinal ganglion cell degeneration |
TWI290470B (en) * | 1999-12-01 | 2007-12-01 | Sankyo Co | The composition for treating glaucoma |
EP1568382B1 (fr) * | 2002-11-18 | 2013-11-06 | Santen Pharmaceutical Co., Ltd. | Medicament contre le glaucome comprenant un inhibiteur de la rho-kinase et un betabloquant |
US9649300B2 (en) * | 2013-08-28 | 2017-05-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Inhibition of WNT, TGF beta and Hippo signaling pathways to treat cancer, organ fibrosis and metabolic disorders |
MX2019007434A (es) | 2016-12-21 | 2019-08-16 | Biotheryx Inc | Derivados de tienopirrol para uso en seleccion como diana de proteinas, composiciones, metodos y usos de los mismos. |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3655663A (en) * | 1969-04-21 | 1972-04-11 | Burton K Wasson | 4-(3-secondary amino-2-hydroxy-proxy) 1 2 5-thiadiazoles |
US4911920A (en) * | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
US4797413A (en) * | 1986-05-14 | 1989-01-10 | Merck & Co., Inc. | Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use |
US4863922A (en) * | 1984-12-12 | 1989-09-05 | Merck & Co., Inc. | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use |
EP0189690B1 (fr) * | 1984-12-12 | 1989-03-01 | Merck & Co. Inc. | Sulfonamides aromatiques substitués, leur préparation et compositions ophtalmiques les contenant |
US4731368A (en) * | 1986-12-08 | 1988-03-15 | Merck & Co., Inc. | Thienopyridine sulfonamides and their ophthalmological formulation |
US4751231A (en) * | 1987-09-16 | 1988-06-14 | Merck & Co., Inc. | Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma agents |
EP0309028A3 (fr) * | 1987-09-16 | 1990-06-27 | Merck & Co. Inc. | Thiéno[2,3-b]furan-2-sulfonamides substituées comme agents antiglaucoma |
US4946859A (en) * | 1989-07-31 | 1990-08-07 | Merck & Co., Inc. | 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide |
US5153192A (en) * | 1990-04-09 | 1992-10-06 | Alcon Laboratories, Inc. | Thiophene sulfonamides useful as carbonic anhydrase inhibitors |
IE911192A1 (en) * | 1990-04-12 | 1991-10-23 | Merck & Co Inc | Substituted aromatic sulfonamides as antiglaucoma agents |
JP2594486B2 (ja) * | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
CA2064160C (fr) * | 1991-03-27 | 1998-08-11 | Paul J. T. Missel | Emploi de polysaccharides gelifiants combines a des substrats finement divises a action de vecteur des medicaments, dans des compositions ophthalmiques a usage local |
RO113612B1 (ro) * | 1991-04-17 | 1998-09-30 | Merck & Co Inc | Compozitie oftalmica |
-
1993
- 1993-02-19 ES ES93906084T patent/ES2118941T3/es not_active Expired - Lifetime
- 1993-02-19 DE DE69320329T patent/DE69320329T2/de not_active Expired - Fee Related
- 1993-02-19 AT AT93906084T patent/ATE169499T1/de not_active IP Right Cessation
- 1993-02-19 AU AU37257/93A patent/AU677577B2/en not_active Ceased
- 1993-02-19 DK DK93906084T patent/DK0625903T3/da active
- 1993-02-19 WO PCT/US1993/001487 patent/WO1993016701A2/fr active IP Right Grant
- 1993-02-19 JP JP5514967A patent/JP2965267B2/ja not_active Expired - Fee Related
- 1993-02-19 EP EP93906084A patent/EP0625903B1/fr not_active Expired - Lifetime
- 1993-02-19 CA CA002129037A patent/CA2129037C/fr not_active Expired - Fee Related
-
1998
- 1998-02-25 JP JP10044090A patent/JPH10324640A/ja active Pending
- 1998-09-24 HK HK98110893A patent/HK1009941A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69320329T2 (de) | 1998-12-24 |
CA2129037C (fr) | 1998-03-24 |
AU3725793A (en) | 1993-09-13 |
ATE169499T1 (de) | 1998-08-15 |
AU677577B2 (en) | 1997-05-01 |
WO1993016701A3 (fr) | 1994-01-06 |
JPH07504899A (ja) | 1995-06-01 |
EP0625903A1 (fr) | 1994-11-30 |
DE69320329D1 (de) | 1998-09-17 |
JPH10324640A (ja) | 1998-12-08 |
ES2118941T3 (es) | 1998-10-01 |
WO1993016701A2 (fr) | 1993-09-02 |
JP2965267B2 (ja) | 1999-10-18 |
DK0625903T3 (da) | 1999-05-10 |
EP0625903B1 (fr) | 1998-08-12 |
CA2129037A1 (fr) | 1993-09-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20040219 |
|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |