DK0625903T3 - Topiske antiglaukompræparater omfattende carbonsyreanhydraseinhibitorer og beta-blokkere - Google Patents

Topiske antiglaukompræparater omfattende carbonsyreanhydraseinhibitorer og beta-blokkere

Info

Publication number
DK0625903T3
DK0625903T3 DK93906084T DK93906084T DK0625903T3 DK 0625903 T3 DK0625903 T3 DK 0625903T3 DK 93906084 T DK93906084 T DK 93906084T DK 93906084 T DK93906084 T DK 93906084T DK 0625903 T3 DK0625903 T3 DK 0625903T3
Authority
DK
Denmark
Prior art keywords
beta
blockers
carboxylic acid
compositions
glaucoma
Prior art date
Application number
DK93906084T
Other languages
English (en)
Inventor
Thomas Robert Dean
Louis Desantis Jr
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of DK0625903T3 publication Critical patent/DK0625903T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK93906084T 1992-02-21 1993-02-19 Topiske antiglaukompræparater omfattende carbonsyreanhydraseinhibitorer og beta-blokkere DK0625903T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83986992A 1992-02-21 1992-02-21
PCT/US1993/001487 WO1993016701A2 (en) 1992-02-21 1993-02-19 Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers

Publications (1)

Publication Number Publication Date
DK0625903T3 true DK0625903T3 (da) 1999-05-10

Family

ID=25280847

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93906084T DK0625903T3 (da) 1992-02-21 1993-02-19 Topiske antiglaukompræparater omfattende carbonsyreanhydraseinhibitorer og beta-blokkere

Country Status (10)

Country Link
EP (1) EP0625903B1 (da)
JP (2) JP2965267B2 (da)
AT (1) ATE169499T1 (da)
AU (1) AU677577B2 (da)
CA (1) CA2129037C (da)
DE (1) DE69320329T2 (da)
DK (1) DK0625903T3 (da)
ES (1) ES2118941T3 (da)
HK (1) HK1009941A1 (da)
WO (1) WO1993016701A2 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG84487A1 (en) 1991-04-17 2001-11-20 Merck & Co Inc Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a b-adrenergic antagonist
US6316443B1 (en) 1994-08-04 2001-11-13 Merck & Co., Inc. Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a β-adrenergic antagonist
US6071904A (en) * 1996-12-11 2000-06-06 Alcon Laboratories, Inc. Process for manufacturing ophthalmic suspensions
WO1999000133A1 (en) * 1997-06-26 1999-01-07 Merck & Co., Inc. Method for optimizing retinal and optic nerve health
DE69928771T2 (de) * 1998-01-23 2006-09-07 Einar Stefansson Carbonische anhydrase inhibitor zur steigerung des sauerstoffdrucks im sehnerv und retina
WO2000007584A2 (en) * 1998-08-04 2000-02-17 Wisconsin Alumni Research Foundation Method of reducing retinal ganglion cell degeneration
TWI290470B (en) * 1999-12-01 2007-12-01 Sankyo Co The composition for treating glaucoma
AU2003280812A1 (en) * 2002-11-18 2004-06-15 Santen Pharmaceutical Co., Ltd. REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND Beta-BLOCKER
US9649300B2 (en) * 2013-08-28 2017-05-16 University of Pittsburgh—of the Commonwealth System of Higher Education Inhibition of WNT, TGF beta and Hippo signaling pathways to treat cancer, organ fibrosis and metabolic disorders
US10040804B2 (en) 2016-12-21 2018-08-07 Biotheryx, Inc. Compounds targeting proteins, compositions, methods, and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3655663A (en) * 1969-04-21 1972-04-11 Burton K Wasson 4-(3-secondary amino-2-hydroxy-proxy) 1 2 5-thiadiazoles
US4911920A (en) * 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
ATE41002T1 (de) * 1984-12-12 1989-03-15 Merck & Co Inc Substituierte aromatische sulfonamide, ihre herstellung und diese enthaltende ophthalmische zubereitungen.
US4863922A (en) * 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
US4797413A (en) * 1986-05-14 1989-01-10 Merck & Co., Inc. Thieno thiopyran sulfonamide derivatives, pharmaceutical compositions and use
US4731368A (en) * 1986-12-08 1988-03-15 Merck & Co., Inc. Thienopyridine sulfonamides and their ophthalmological formulation
EP0309028A3 (en) * 1987-09-16 1990-06-27 Merck & Co. Inc. Substituted thieno(2,3-b)furan-2-sulfonamides as antiglaucoma agents
US4751231A (en) * 1987-09-16 1988-06-14 Merck & Co., Inc. Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma agents
US4946859A (en) * 1989-07-31 1990-08-07 Merck & Co., Inc. 4-(2-methyl-2-hydroxypropylamino)-5,6-dihydrothieno-[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide
US5153192A (en) * 1990-04-09 1992-10-06 Alcon Laboratories, Inc. Thiophene sulfonamides useful as carbonic anhydrase inhibitors
IE911192A1 (en) * 1990-04-12 1991-10-23 Merck & Co Inc Substituted aromatic sulfonamides as antiglaucoma agents
ATE141502T1 (de) * 1991-01-15 1996-09-15 Alcon Lab Inc Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen
JP2536806B2 (ja) * 1991-03-27 1996-09-25 アルコン ラボラトリーズ インコーポレイテッド ゲル化多糖類と微粉砕された薬剤担体とを組み合わせた局部眼科用組成物
RO113612B1 (ro) * 1991-04-17 1998-09-30 Merck & Co Inc Compozitie oftalmica

Also Published As

Publication number Publication date
CA2129037C (en) 1998-03-24
DE69320329D1 (de) 1998-09-17
AU3725793A (en) 1993-09-13
AU677577B2 (en) 1997-05-01
EP0625903A1 (en) 1994-11-30
JP2965267B2 (ja) 1999-10-18
WO1993016701A2 (en) 1993-09-02
DE69320329T2 (de) 1998-12-24
HK1009941A1 (en) 1999-06-11
WO1993016701A3 (en) 1994-01-06
JPH10324640A (ja) 1998-12-08
ES2118941T3 (es) 1998-10-01
ATE169499T1 (de) 1998-08-15
JPH07504899A (ja) 1995-06-01
CA2129037A1 (en) 1993-09-02
EP0625903B1 (en) 1998-08-12

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