HK1006147A1 - Echo contrast means - Google Patents

Echo contrast means

Info

Publication number
HK1006147A1
HK1006147A1 HK98105041A HK98105041A HK1006147A1 HK 1006147 A1 HK1006147 A1 HK 1006147A1 HK 98105041 A HK98105041 A HK 98105041A HK 98105041 A HK98105041 A HK 98105041A HK 1006147 A1 HK1006147 A1 HK 1006147A1
Authority
HK
Hong Kong
Prior art keywords
echo contrast
contrast means
echo
stabilisation
demonstration
Prior art date
Application number
HK98105041A
Other languages
English (en)
Inventor
Klaus-Dieter Beller
Rudolf Linder
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6422745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1006147(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of HK1006147A1 publication Critical patent/HK1006147A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
HK98105041A 1991-01-09 1998-06-08 Echo contrast means HK1006147A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4100470A DE4100470A1 (de) 1991-01-09 1991-01-09 Echokontrastmittel
PCT/EP1992/000012 WO1992011873A1 (de) 1991-01-09 1992-01-04 Echokontrastmittel

Publications (1)

Publication Number Publication Date
HK1006147A1 true HK1006147A1 (en) 1999-02-12

Family

ID=6422745

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98105041A HK1006147A1 (en) 1991-01-09 1998-06-08 Echo contrast means

Country Status (25)

Country Link
US (1) US5599523A (uk)
EP (2) EP0566601B2 (uk)
JP (1) JP3290655B2 (uk)
KR (1) KR100203221B1 (uk)
AT (1) ATE126708T1 (uk)
AU (1) AU652803B2 (uk)
BG (1) BG61667B2 (uk)
CA (1) CA2098915C (uk)
CZ (1) CZ280939B6 (uk)
DE (3) DE4100470A1 (uk)
DK (1) DK0566601T4 (uk)
ES (1) ES2079176T5 (uk)
FI (1) FI119913B (uk)
GR (1) GR3017925T3 (uk)
HK (1) HK1006147A1 (uk)
HU (1) HU220763B1 (uk)
IE (1) IE70131B1 (uk)
IL (1) IL100607A (uk)
NZ (1) NZ241246A (uk)
PL (1) PL167253B1 (uk)
RU (1) RU2091079C1 (uk)
SK (1) SK278776B6 (uk)
UA (1) UA27121C2 (uk)
WO (1) WO1992011873A1 (uk)
ZA (1) ZA92118B (uk)

Families Citing this family (55)

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US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US5578292A (en) 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
IN172208B (uk) * 1990-04-02 1993-05-01 Sint Sa
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
US5993805A (en) 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
RU2114637C1 (ru) * 1991-09-17 1998-07-10 Сонус Фармасьютикалз, Инк. Биосовместимая контрастная среда и способ получения ультразвукового изображения
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
US6875420B1 (en) 1991-09-17 2005-04-05 Amersham Health As Method of ultrasound imaging
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
US5464696A (en) * 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
GB9221329D0 (en) 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
ATE200985T1 (de) 1993-01-25 2001-05-15 Sonus Pharma Inc Phase-stift kolloide zur verwendung als ultraschallkontrastmittel
US5716597A (en) * 1993-06-04 1998-02-10 Molecular Biosystems, Inc. Emulsions as contrast agents and method of use
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
CA2164813C (en) 1993-07-30 2009-11-24 Ernest G. Schutt Stabilized microbubble compositions for ultrasound
DE4328642A1 (de) * 1993-08-26 1995-03-02 Byk Gulden Lomberg Chem Fab Ultraschallkontrastmittel
GB9318288D0 (en) * 1993-09-03 1993-10-20 Nycomed Imaging As Improvements in or relating to contrast agents
AU679295B2 (en) 1993-12-15 1997-06-26 Bracco Suisse S.A. Gas mixtures useful as ultrasound contrast media
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
GB9423419D0 (en) 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
WO2004073750A1 (en) 1995-06-07 2004-09-02 Harald Dugstad Improvements in or relating to contrast agents
US5804162A (en) * 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
EE04224B1 (et) * 1996-02-19 2004-02-16 Nycomed Imaging As Gaasi mikromullide dispersioon ja selle lüofiliseeritud jääk, ultraheli kontrastaine ja selle valmistamismeetod, mikromulle eraldav maatriks ning ultraheli kontrastaine kompositsioon
ATE266426T1 (de) * 1996-03-05 2004-05-15 Acusphere Inc Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel
DE19626530A1 (de) * 1996-07-02 1998-01-15 Byk Gulden Lomberg Chem Fab MR-Kontrastmittelzubereitungen
NZ334365A (en) * 1996-08-02 1999-10-28 Nycomed Imaging As Use of a contrast agent comprising microbubbles of biocompatible gas stabilised by opsonisable amphiphilic material for ultrasound imaging of the liver
US6017310A (en) * 1996-09-07 2000-01-25 Andaris Limited Use of hollow microcapsules
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
US6054118A (en) * 1997-01-22 2000-04-25 Nycomed Imaging As Contrast agents comprising two types of gas-containing microparticles
GB9701237D0 (en) * 1997-01-22 1997-03-12 Nycomed Imaging As Improvements in or relating to contrast agents
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19805012A1 (de) * 1998-02-07 1999-08-12 Thomas Gieselmann Kontrastmittel zur Verwendung als Diagnostikum bei bildgebenden Verfahren sowie seine Herstellung
GB9912356D0 (en) 1999-05-26 1999-07-28 Btg Int Ltd Generation of microfoam
US8512680B2 (en) 2001-08-08 2013-08-20 Btg International Ltd. Injectables in foam, new pharmaceutical applications
US8048439B2 (en) 2003-11-17 2011-11-01 Btg International Ltd. Therapeutic foam
EA009362B1 (ru) 2003-11-17 2007-12-28 Би Ти Джи Интернэшнл Лимитед Терапевтическая пена
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
GB0509824D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Therapeutic foam
WO2007070827A2 (en) * 2005-12-15 2007-06-21 Bristol-Myers Squibb Pharma Company Contrast agents for myocardium perfusion imaging

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
EP0318081B1 (en) * 1987-11-27 1991-07-24 Akzo N.V. Stabilization of antibodies
IN172208B (uk) * 1990-04-02 1993-05-01 Sint Sa

Also Published As

Publication number Publication date
EP0566601B1 (de) 1995-08-23
IE70131B1 (en) 1996-10-30
FI119913B (fi) 2009-05-15
RU2091079C1 (ru) 1997-09-27
US5599523A (en) 1997-02-04
HUT64239A (en) 1993-12-28
EP0494615A1 (de) 1992-07-15
FI933137A0 (fi) 1993-07-08
CZ178093A3 (en) 1994-04-13
KR100203221B1 (ko) 1999-06-15
EP0566601B2 (de) 2007-02-21
IL100607A (en) 1996-07-23
ATE126708T1 (de) 1995-09-15
DE59203392D1 (de) 1995-09-28
AU652803B2 (en) 1994-09-08
BG61667B2 (bg) 1998-02-27
DE4100470A1 (de) 1992-07-16
WO1992011873A1 (de) 1992-07-23
UA27121C2 (uk) 2000-02-28
ES2079176T3 (es) 1996-01-01
JP3290655B2 (ja) 2002-06-10
HU9301703D0 (en) 1993-09-28
KR930703023A (ko) 1993-11-29
IE920038A1 (en) 1992-07-15
SK278776B6 (sk) 1998-02-04
ZA92118B (en) 1992-08-26
ES2079176T5 (es) 2007-10-16
DK0566601T4 (da) 2007-05-29
FI933137A (fi) 1993-07-08
DE4290068D2 (de) 1993-10-07
EP0566601A1 (de) 1993-10-27
NZ241246A (en) 1994-01-26
JP2000509363A (ja) 2000-07-25
SK72993A3 (en) 1994-04-06
CZ280939B6 (cs) 1996-05-15
CA2098915A1 (en) 1992-07-10
IL100607A0 (en) 1992-09-06
CA2098915C (en) 2005-05-17
AU1154792A (en) 1992-08-17
DK0566601T3 (da) 1995-12-18
HU220763B1 (hu) 2002-05-28
PL167253B1 (pl) 1995-08-31
GR3017925T3 (en) 1996-01-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)