HK1002009A1 - Bisconjugates comprising two saccharides and a spacer - Google Patents

Bisconjugates comprising two saccharides and a spacer

Info

Publication number
HK1002009A1
HK1002009A1 HK98101022A HK98101022A HK1002009A1 HK 1002009 A1 HK1002009 A1 HK 1002009A1 HK 98101022 A HK98101022 A HK 98101022A HK 98101022 A HK98101022 A HK 98101022A HK 1002009 A1 HK1002009 A1 HK 1002009A1
Authority
HK
Hong Kong
Prior art keywords
spacer
saccharides
bisconjugates
saccharide
bisconjugate
Prior art date
Application number
HK98101022A
Other languages
English (en)
Inventor
Constant Van Boeckel
Peter Grootenhuis
Maurice Petitou
Original Assignee
Akzo Nobel Nv
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv, Sanofi Synthelabo filed Critical Akzo Nobel Nv
Publication of HK1002009A1 publication Critical patent/HK1002009A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
HK98101022A 1993-09-01 1998-02-11 Bisconjugates comprising two saccharides and a spacer HK1002009A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93202562 1993-09-01

Publications (1)

Publication Number Publication Date
HK1002009A1 true HK1002009A1 (en) 1998-07-24

Family

ID=8214074

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98101022A HK1002009A1 (en) 1993-09-01 1998-02-11 Bisconjugates comprising two saccharides and a spacer

Country Status (20)

Country Link
US (1) US5705489A (zh)
EP (1) EP0649854B1 (zh)
JP (1) JP3918953B2 (zh)
KR (1) KR100365578B1 (zh)
AT (1) ATE190619T1 (zh)
AU (1) AU679084B2 (zh)
BR (1) BR1100612A (zh)
CA (1) CA2131229C (zh)
DE (1) DE69423414T2 (zh)
DK (1) DK0649854T3 (zh)
ES (1) ES2147216T3 (zh)
FI (1) FI113540B (zh)
GR (1) GR3033410T3 (zh)
HK (1) HK1002009A1 (zh)
HU (1) HU227279B1 (zh)
NO (1) NO301984B1 (zh)
NZ (1) NZ264340A (zh)
PT (1) PT649854E (zh)
TW (1) TW349951B (zh)
ZA (1) ZA946673B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9201440A (nl) * 1992-08-11 1994-03-01 Univ Leiden Triantennaire clusterglycosiden, hun bereiding en toepassing.
DE19624705A1 (de) * 1996-06-20 1998-01-08 Deutsches Krebsforsch Dendrimere auf Saccharid-Basis
FR2751334B1 (fr) 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2773801B1 (fr) * 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
US6486129B1 (en) * 1998-06-17 2002-11-26 Akzo Nobel N.V. Antithrombotic compounds
WO2001012675A1 (fr) * 1999-08-10 2001-02-22 Seikagaku Corporation Derives de glycosaminoglycane et leur utilisation
TWI289566B (en) * 1999-12-07 2007-11-11 N.V.Organon Antithrombotic compound
DE10041221A1 (de) * 2000-08-22 2002-03-14 Deutsches Krebsforsch Verfahren zur Herstellung von wasserlöslichen Saccharidkonjugaten und Saccharidmimetika durch Diels-Alder-Reaktion und ihre Verwendung als Therapeutika oder Diagnostika
EP1574516A1 (en) 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
EP1886696A1 (en) * 2006-08-03 2008-02-13 Endotis Pharma Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins
EP2421878B1 (en) * 2008-10-03 2017-06-14 Glycan Biosciences LLC Anionic oligosaccharide conjugates
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
WO2012042123A1 (fr) 2010-09-10 2012-04-05 Sanofi Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
EP2578594A1 (en) * 2011-10-04 2013-04-10 Sanofi Process of preparation of L-iduronic acid comprising a decarboxylation/intramolecular cyclisation tandem reaction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818816A (en) * 1981-04-28 1989-04-04 Choay, S.A. Process for the organic synthesis of oligosaccharides and derivatives thereof
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DE3734853A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Bis-aldonsaeureamide und verfahren zu ihrer herstellung
EP0337327A1 (en) * 1988-04-09 1989-10-18 Bioiberica, S.A. Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin
EP0347964A1 (en) * 1988-06-21 1989-12-27 Akzo N.V. New oligosaccharides with internal spacer
DE69100275T2 (de) * 1990-04-23 1993-12-02 Akzo Nv Eine Trisaccharideinheit enthaltende Kohlenhydratderivate.

Also Published As

Publication number Publication date
CA2131229A1 (en) 1995-03-02
KR100365578B1 (ko) 2003-03-19
HUT69163A (en) 1995-08-28
BR1100612A (pt) 2003-02-25
KR950008528A (ko) 1995-04-19
GR3033410T3 (en) 2000-09-29
FI944001A0 (fi) 1994-08-31
ATE190619T1 (de) 2000-04-15
JPH07304787A (ja) 1995-11-21
EP0649854A1 (en) 1995-04-26
DK0649854T3 (da) 2000-07-03
ES2147216T3 (es) 2000-09-01
CA2131229C (en) 2005-04-12
NZ264340A (en) 1995-04-27
TW349951B (en) 1999-01-11
ZA946673B (en) 1995-04-21
FI944001A (fi) 1995-03-02
NO943222L (no) 1995-03-02
NO301984B1 (no) 1998-01-05
HU9402514D0 (en) 1994-10-28
AU7161094A (en) 1995-03-16
PT649854E (pt) 2000-07-31
DE69423414D1 (de) 2000-04-20
AU679084B2 (en) 1997-06-19
DE69423414T2 (de) 2000-09-21
HU227279B1 (en) 2011-01-28
US5705489A (en) 1998-01-06
NO943222D0 (no) 1994-08-31
EP0649854B1 (en) 2000-03-15
FI113540B (fi) 2004-05-14
JP3918953B2 (ja) 2007-05-23

Similar Documents

Publication Publication Date Title
GR3033410T3 (en) Bisconjugates comprising two saccharides and a spacer.
AU2764592A (en) Beta -1,3-glucan polysaccharides, compositions, and their preparation and uses
DE69020635T2 (de) Übertragungssystem zwischen Haupteinheit und zusätzlichen Prozesseinheiten.
NO304966B1 (no) Blandinger inneholdende hypokariogene, hydrogenerte sakkarider og deres fremstilling
GB9020231D0 (en) Glazing bar systems
ZA935730B (en) Glucans with immunostimulant activity.
DK0960132T3 (da) Polysaccharid, mikroorganisme og fremgangsmåde til fremstilling deraf, præparat med indhold deraf samt anvendelse
DE3570353D1 (en) Angle-bar supporting shelves, panels or the like, and furniture incorporating the same
EP0705059A4 (en) GLYCOSIDES SEQUENCING CHOLESTEROLE INHIBITING INTESTINAL ABSORPTION
NO177426C (no) Kitin- eller kitosanoligomer og fremgangsmåte til fremstilling derav
HUP9700852A2 (en) Carbohydrate derivatives with antithrombotic activity and pharmaceutical compositions contg. them
NZ238054A (en) Avermectin derivatives having an alkyleneoxy or an ethoxymethoxy spacer between the disaccharide and the aglycone; pesticidal compositions
EP0496351A3 (en) Acid heteropolysaccharide, sulfated polysaccharide and process for producing the same
AU7478191A (en) Endogenous, suramin-induced, sulfated glycosaminoglycans as anti-cancer agents in humans
EP0671526A3 (de) Richtbeschlag zum Geradebiegen verzogener Türen od. dgl.
GB2249284B (en) Reducing transmission through windows or other glazed units
GB2200387B (en) Double-barrel pulse-generating hydraulic monitor
EP0641913A3 (de) Sprossenanordnung für Flächenverkleidungen, insbesondere Fenster-oder Türelemente.
WO1999047694A8 (de) Nucleotidaktivierte di- und oligosaccharide sowie verfahren zu deren herstellung ii
FI971782A (fi) Menetelmä monosakkariditasojen suurentamiseksi tärkkelyksen sokeroituksessa ja siihen tarkoitukseen käyttökelpoisia entsyymeejä
DE69601908D1 (de) Fluorenthaltende Anthracyclinderivate mit Mono- oder Di-0-aminoalkanoylaten Hydroxylgruppen in dem Zuckerrest
TH17897EX (th) บิคอนจูเกตที่ประกอบด้วยแซคคาไรด์สองหน่วยและส่วนคั่น
AU5028799A (en) Products from the reaction of formaldehyde with carbohydrates or carbohydrate derivatives, and use of said products as preservatives
ES1024054U (es) Dispositivo de deslizamiento para puerta de armario.
FR2705395B1 (fr) Double vitrage antivibratoire.

Legal Events

Date Code Title Description
PF Patent in force
CHPA Change of a particular in the register (except of change of ownership)
PE Patent expired

Effective date: 20140829