HK1000798A1 - Gabapentin monohydrate and a process for producing the same - Google Patents
Gabapentin monohydrate and a process for producing the sameInfo
- Publication number
- HK1000798A1 HK1000798A1 HK97102376A HK97102376A HK1000798A1 HK 1000798 A1 HK1000798 A1 HK 1000798A1 HK 97102376 A HK97102376 A HK 97102376A HK 97102376 A HK97102376 A HK 97102376A HK 1000798 A1 HK1000798 A1 HK 1000798A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- producing
- same
- novel
- gabapentin
- gabapentin monohydrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/188,819 US4894476A (en) | 1988-05-02 | 1988-05-02 | Gabapentin monohydrate and a process for producing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1000798A1 true HK1000798A1 (en) | 1998-05-01 |
Family
ID=22694659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK97102376A HK1000798A1 (en) | 1988-05-02 | 1997-12-10 | Gabapentin monohydrate and a process for producing the same |
Country Status (12)
Country | Link |
---|---|
US (1) | US4894476A (de) |
EP (1) | EP0340677B1 (de) |
JP (1) | JP2619951B2 (de) |
AT (1) | ATE101116T1 (de) |
AU (1) | AU624130B2 (de) |
CA (1) | CA1306755C (de) |
DE (1) | DE68912819T2 (de) |
DK (1) | DK175400B1 (de) |
ES (1) | ES2061774T3 (de) |
FI (1) | FI892067A (de) |
HK (1) | HK1000798A1 (de) |
IE (1) | IE62958B1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3928182A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von gabapentin |
PH27359A (en) * | 1989-08-25 | 1993-06-21 | Warner Lambert Co | Process for cyclic amino acid anticonvulsant compounds |
DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
DE3928183A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Lactamfreie cyclische aminosaeuren |
EP0458751A1 (de) * | 1990-05-25 | 1991-11-27 | Warner-Lambert Company | System zur Freisetzung von cyclischen Aminosäuren mit verbessertem Geschmack, Struktur und Komprimierbarkeit |
IL125544A (en) * | 1996-03-14 | 2002-03-10 | Warner Lambert Co | Transformed cyclic amino acids and pharmaceutical preparations containing them |
US6372792B1 (en) | 1996-04-26 | 2002-04-16 | Guy Chouinard | Method for treating anxiety, anxiety disorders and insomnia |
US6255526B1 (en) | 1996-12-24 | 2001-07-03 | Teva Pharmaceutical Industries Ltd. | Preparation of gabapentin |
AU9318398A (en) | 1997-10-07 | 1999-04-27 | Warner-Lambert Company | Process for preparing a cyclic amino acid anticonvulsant compound |
ES2137137B1 (es) | 1998-05-25 | 2000-08-16 | Medichem Sa | Nuevo polimorfo de gabapentina no hidratada, su procedimiento de obtencion y su utilizacion para la obtencion de gabapentina de calidad farmaceutica. |
ITMI981535A1 (it) * | 1998-07-03 | 2000-01-03 | Zambon Spa | Processo per la preparazione di gabapentina |
HU225502B1 (en) * | 1998-12-29 | 2007-01-29 | Richter Gedeon Vegyeszet | Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates |
IT1311984B1 (it) | 1999-03-26 | 2002-03-22 | Bioindustria Lab Italiano Medi | Procedimento per la preparzione di gabapentin. |
EP1169060B1 (de) * | 1999-04-09 | 2005-08-31 | Euro-Celtique S.A. | Natrium kanalblocker zusammensetzungen und deren verwendung |
ES2164527B1 (es) * | 1999-04-26 | 2003-04-01 | Medichen S A | Procedimiento de obtencion de gabapentina de calidad farmaceutica. |
US6294198B1 (en) | 1999-08-24 | 2001-09-25 | Purepac Pharmaceutical Co. | Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same |
US6333352B1 (en) | 2000-04-05 | 2001-12-25 | Mimicking Man Manually, Inc. | Method of treating benign positional vertigo |
JP2003535885A (ja) * | 2000-06-16 | 2003-12-02 | テバ ファーマシューティカル インダストリーズ リミティド | 制御された範囲内にpHを持つ安定なギャバペンチン |
US6531509B2 (en) | 2000-06-16 | 2003-03-11 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 20 ppm of chlorine ion |
EP1384473A1 (de) * | 2000-06-16 | 2004-01-28 | Teva Pharmaceutical Industries Ltd. | Stabiles Gabapentin das mehr als 20 ppm Chlor enthält |
ITMI20011132A1 (it) | 2001-05-29 | 2002-11-29 | Procos Spa | Procedimento per la preparazione dell'acido 1-amminometil-1-cicloesanacetico |
JP4350508B2 (ja) * | 2001-09-03 | 2009-10-21 | ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー | ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途 |
US6800782B2 (en) * | 2001-10-09 | 2004-10-05 | Warner-Lambert Co. | Anhydrous crystalline forms of gabapentin |
TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
US20070184104A1 (en) * | 2001-10-25 | 2007-08-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
US20030119908A1 (en) * | 2001-12-21 | 2003-06-26 | Zambon Group S.P.A. | Stable gabapentin compositions |
US6682759B2 (en) | 2002-02-01 | 2004-01-27 | Depomed, Inc. | Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs |
US7217696B2 (en) | 2002-02-28 | 2007-05-15 | A & D Bioscience, Inc. | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof |
WO2003079980A2 (en) * | 2002-03-19 | 2003-10-02 | A & D Bioscience, Inc. | Caboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof |
US20050255038A1 (en) * | 2002-04-12 | 2005-11-17 | A And D Bioscience, Inc. | Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents and uses thereof |
AU2003262383A1 (en) * | 2002-04-16 | 2003-11-03 | Taro Pharmaceutical Industries Ltd. | Process for preparing gabapentin |
EP1549323A2 (de) * | 2002-05-07 | 2005-07-06 | A & D Bioscience, Inc. | Konjugate mit einem wirkstoff für das zentrale nervensystem |
US20050215487A1 (en) * | 2002-06-27 | 2005-09-29 | Holick Michael F | Conjugates comprising an nsaid and a sugar and uses thereof |
CA2472815A1 (en) * | 2002-11-18 | 2004-06-03 | Nicholas Piramal India Limited | Improved process for preparation of gabapentin |
US20040214893A1 (en) * | 2003-04-11 | 2004-10-28 | Matthew Peterson | Gabapentin compositions |
WO2004093780A2 (en) * | 2003-04-21 | 2004-11-04 | Matrix Laboratories Ltd | Process for the preparation of gabapentin form-ii |
US20070043236A1 (en) * | 2003-05-19 | 2007-02-22 | Chandiran Thakashina M | Process for preparation of gabapentin |
WO2004106281A1 (en) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Crystalline gabapentin |
US20050013863A1 (en) | 2003-07-18 | 2005-01-20 | Depomed, Inc., A Corporation Of The State Of California | Dual drug dosage forms with improved separation of drugs |
US20050187295A1 (en) * | 2004-02-19 | 2005-08-25 | Surendra Kalyan | Processes for the preparation of gabapentin |
ITMI20040579A1 (it) * | 2004-03-25 | 2004-06-25 | Zambon Spa | Processo di preparazione di gabapentina |
GB0416228D0 (en) | 2004-07-20 | 2004-08-25 | Sandoz Ind Products S A | Process for the preparation of gabapentin |
BRPI0515154A (pt) * | 2004-09-10 | 2008-07-08 | Newron Pharm Spa | uso de (halobenzilóxi)benzilamino-propanamidas para a fabricação de medicamentos ativos, compostos e composição farmacêutica |
ITMI20042418A1 (it) * | 2004-12-17 | 2005-03-17 | Zambon Spa | Processo per la purificazione della gabapentina |
US7071356B1 (en) * | 2005-12-01 | 2006-07-04 | Isp Investments Inc. | Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
US20090176882A1 (en) * | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
US20110217387A1 (en) * | 2008-05-16 | 2011-09-08 | Axis, Inc. | Pharmaceutical composition for treatment of fibromyalgia |
US8431739B2 (en) | 2010-06-14 | 2013-04-30 | Divi's Laboratories, Ltd. | Process for the preparation of gabapentin |
WO2015144825A1 (en) | 2014-03-27 | 2015-10-01 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Oral liquid pharmaceutical solution of gabapentin |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
US4014175A (en) * | 1975-05-05 | 1977-03-29 | Brink Douglas F | Cable and pipe laying machine |
US4087594A (en) * | 1977-03-21 | 1978-05-02 | Gte Laboratories, Incorporated | Reactivation of primary electrochemical cells |
PH27359A (en) * | 1989-08-25 | 1993-06-21 | Warner Lambert Co | Process for cyclic amino acid anticonvulsant compounds |
-
1988
- 1988-05-02 US US07/188,819 patent/US4894476A/en not_active Expired - Lifetime
-
1989
- 1989-04-10 IE IE114289A patent/IE62958B1/en not_active IP Right Cessation
- 1989-04-11 AU AU32678/89A patent/AU624130B2/en not_active Expired
- 1989-04-11 CA CA000596341A patent/CA1306755C/en not_active Expired - Fee Related
- 1989-04-28 ES ES89107795T patent/ES2061774T3/es not_active Expired - Lifetime
- 1989-04-28 AT AT89107795T patent/ATE101116T1/de not_active IP Right Cessation
- 1989-04-28 DE DE68912819T patent/DE68912819T2/de not_active Expired - Lifetime
- 1989-04-28 FI FI892067A patent/FI892067A/fi not_active IP Right Cessation
- 1989-04-28 EP EP89107795A patent/EP0340677B1/de not_active Expired - Lifetime
- 1989-05-01 JP JP1109264A patent/JP2619951B2/ja not_active Expired - Fee Related
- 1989-05-01 DK DK198902126A patent/DK175400B1/da not_active IP Right Cessation
-
1997
- 1997-12-10 HK HK97102376A patent/HK1000798A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK212689A (da) | 1989-11-03 |
EP0340677A2 (de) | 1989-11-08 |
ES2061774T3 (es) | 1994-12-16 |
CA1306755C (en) | 1992-08-25 |
EP0340677B1 (de) | 1994-02-02 |
IE891142L (en) | 1989-11-02 |
FI892067A0 (fi) | 1989-04-28 |
DE68912819D1 (de) | 1994-03-17 |
AU3267889A (en) | 1989-11-02 |
US4894476A (en) | 1990-01-16 |
ATE101116T1 (de) | 1994-02-15 |
EP0340677A3 (en) | 1990-12-27 |
DK212689D0 (da) | 1989-05-01 |
JPH0211546A (ja) | 1990-01-16 |
DK175400B1 (da) | 2004-09-27 |
AU624130B2 (en) | 1992-06-04 |
IE62958B1 (en) | 1995-03-08 |
JP2619951B2 (ja) | 1997-06-11 |
DE68912819T2 (de) | 1994-05-19 |
FI892067A (fi) | 1989-11-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20090427 |