DK212689A - Gabapentinmonohydrat og fremgangsmaade til fremstilling deraf - Google Patents
Gabapentinmonohydrat og fremgangsmaade til fremstilling deraf Download PDFInfo
- Publication number
- DK212689A DK212689A DK212689A DK212689A DK212689A DK 212689 A DK212689 A DK 212689A DK 212689 A DK212689 A DK 212689A DK 212689 A DK212689 A DK 212689A DK 212689 A DK212689 A DK 212689A
- Authority
- DK
- Denmark
- Prior art keywords
- gabapentin
- procedures
- preparing
- mono hydrate
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK200200056A DK175127B1 (da) | 1988-05-02 | 2002-01-15 | Gabapentin monohydrat og fremgangsmåde til fremstilling deraf |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/188,819 US4894476A (en) | 1988-05-02 | 1988-05-02 | Gabapentin monohydrate and a process for producing the same |
US18881988 | 1988-05-02 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK212689D0 DK212689D0 (da) | 1989-05-01 |
DK212689A true DK212689A (da) | 1989-11-03 |
DK175400B1 DK175400B1 (da) | 2004-09-27 |
Family
ID=22694659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198902126A DK175400B1 (da) | 1988-05-02 | 1989-05-01 | Gabapentin, monohydrat |
Country Status (12)
Country | Link |
---|---|
US (1) | US4894476A (da) |
EP (1) | EP0340677B1 (da) |
JP (1) | JP2619951B2 (da) |
AT (1) | ATE101116T1 (da) |
AU (1) | AU624130B2 (da) |
CA (1) | CA1306755C (da) |
DE (1) | DE68912819T2 (da) |
DK (1) | DK175400B1 (da) |
ES (1) | ES2061774T3 (da) |
FI (1) | FI892067A (da) |
HK (1) | HK1000798A1 (da) |
IE (1) | IE62958B1 (da) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU633612B2 (en) * | 1989-08-25 | 1993-02-04 | Warner-Lambert Company | Improved process for cyclic amino acid anticonvulsant compounds |
DE3928183A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Lactamfreie cyclische aminosaeuren |
DE3928182A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von gabapentin |
DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
EP0458751A1 (en) * | 1990-05-25 | 1991-11-27 | Warner-Lambert Company | Delivery system for cyclic amino acids with improved taste, texture and compressibility |
KR100512506B1 (ko) * | 1996-03-14 | 2005-12-21 | 워너-램버트 캄파니 엘엘씨 | 제약제제로서신규한치환시클릭아미노산 |
US6372792B1 (en) | 1996-04-26 | 2002-04-16 | Guy Chouinard | Method for treating anxiety, anxiety disorders and insomnia |
US6255526B1 (en) | 1996-12-24 | 2001-07-03 | Teva Pharmaceutical Industries Ltd. | Preparation of gabapentin |
AU9318398A (en) | 1997-10-07 | 1999-04-27 | Warner-Lambert Company | Process for preparing a cyclic amino acid anticonvulsant compound |
ES2137137B1 (es) | 1998-05-25 | 2000-08-16 | Medichem Sa | Nuevo polimorfo de gabapentina no hidratada, su procedimiento de obtencion y su utilizacion para la obtencion de gabapentina de calidad farmaceutica. |
ITMI981535A1 (it) * | 1998-07-03 | 2000-01-03 | Zambon Spa | Processo per la preparazione di gabapentina |
HU225502B1 (en) * | 1998-12-29 | 2007-01-29 | Richter Gedeon Vegyeszet | Process for producing 1-(amino-metyl)-cyclohexene-acetic-acid and intermediates |
IT1311984B1 (it) * | 1999-03-26 | 2002-03-22 | Bioindustria Lab Italiano Medi | Procedimento per la preparzione di gabapentin. |
EP1169060B1 (en) * | 1999-04-09 | 2005-08-31 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
ES2164527B1 (es) * | 1999-04-26 | 2003-04-01 | Medichen S A | Procedimiento de obtencion de gabapentina de calidad farmaceutica. |
US6294198B1 (en) | 1999-08-24 | 2001-09-25 | Purepac Pharmaceutical Co. | Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same |
US6333352B1 (en) | 2000-04-05 | 2001-12-25 | Mimicking Man Manually, Inc. | Method of treating benign positional vertigo |
EP1384473A1 (en) * | 2000-06-16 | 2004-01-28 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 20 ppm of chlorine ion |
WO2001097612A1 (en) * | 2000-06-16 | 2001-12-27 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 2o ppm of chlorine ion |
NZ523546A (en) * | 2000-06-16 | 2005-04-29 | Teva Pharma | Stable pharmaceutical compositions of gabapentin having PH within the range 6.8 to 7.3 comprising less than 0.5% by weight of a corresponding lactum |
ITMI20011132A1 (it) | 2001-05-29 | 2002-11-29 | Procos Spa | Procedimento per la preparazione dell'acido 1-amminometil-1-cicloesanacetico |
PT1423168E (pt) | 2001-09-03 | 2006-05-31 | Newron Pharm Spa | Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico |
US6800782B2 (en) * | 2001-10-09 | 2004-10-05 | Warner-Lambert Co. | Anhydrous crystalline forms of gabapentin |
US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
TWI312285B (en) | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
US7612112B2 (en) * | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
US20070184104A1 (en) * | 2001-10-25 | 2007-08-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
US20030119908A1 (en) * | 2001-12-21 | 2003-06-26 | Zambon Group S.P.A. | Stable gabapentin compositions |
US6682759B2 (en) | 2002-02-01 | 2004-01-27 | Depomed, Inc. | Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs |
WO2003073988A2 (en) | 2002-02-28 | 2003-09-12 | A & D Bioscience, Inc. | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof |
WO2003079980A2 (en) * | 2002-03-19 | 2003-10-02 | A & D Bioscience, Inc. | Caboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof |
WO2003086475A1 (en) * | 2002-04-12 | 2003-10-23 | A & D Bioscience, Inc. | Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents, and uses thereof |
US20040034248A1 (en) * | 2002-04-16 | 2004-02-19 | Taro Pharmaceutical Industries, Ltd. | Process for preparing gabapentin |
CA2484891A1 (en) * | 2002-05-07 | 2003-11-20 | A & D Bioscience, Inc. | Conjugates comprising central nervous system active drug |
US20050215487A1 (en) * | 2002-06-27 | 2005-09-29 | Holick Michael F | Conjugates comprising an nsaid and a sugar and uses thereof |
AU2002356424A1 (en) * | 2002-11-18 | 2004-06-15 | Nicholas Piramal India Limited | Improved process for preparation of gabapentin |
WO2004091278A2 (en) * | 2003-04-11 | 2004-10-28 | Transform Pharmaceuticals, Inc. | Gabapentin compositions |
US7439387B2 (en) * | 2003-04-21 | 2008-10-21 | Matrix Laboratories Ltd. | Process for the preparation of Gabapentin form-II |
US20070043236A1 (en) * | 2003-05-19 | 2007-02-22 | Chandiran Thakashina M | Process for preparation of gabapentin |
WO2004106281A1 (en) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Crystalline gabapentin |
US20050013863A1 (en) | 2003-07-18 | 2005-01-20 | Depomed, Inc., A Corporation Of The State Of California | Dual drug dosage forms with improved separation of drugs |
US20050187295A1 (en) * | 2004-02-19 | 2005-08-25 | Surendra Kalyan | Processes for the preparation of gabapentin |
ITMI20040579A1 (it) * | 2004-03-25 | 2004-06-25 | Zambon Spa | Processo di preparazione di gabapentina |
GB0416228D0 (en) | 2004-07-20 | 2004-08-25 | Sandoz Ind Products S A | Process for the preparation of gabapentin |
CN101018546B (zh) * | 2004-09-10 | 2013-06-12 | 纽朗制药有限公司 | 作为钠和/或钙通道选择性调节剂的(卤代苄氧基)苄氨基-丙酰胺类 |
ITMI20042418A1 (it) * | 2004-12-17 | 2005-03-17 | Zambon Spa | Processo per la purificazione della gabapentina |
US7071356B1 (en) * | 2005-12-01 | 2006-07-04 | Isp Investments Inc. | Process for the preparation of 1-(aminomethyl) cyclohexaneacetic acid |
US20090176882A1 (en) * | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
CA2740029C (en) * | 2008-05-16 | 2016-12-20 | Axis, Inc. | Pharmaceutical composition for treatment of fibromyalgia |
US8431739B2 (en) | 2010-06-14 | 2013-04-30 | Divi's Laboratories, Ltd. | Process for the preparation of gabapentin |
EP2923694B1 (en) | 2014-03-27 | 2018-11-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral liquid pharmaceutical solution of gabapentin |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
US4014175A (en) * | 1975-05-05 | 1977-03-29 | Brink Douglas F | Cable and pipe laying machine |
US4087594A (en) * | 1977-03-21 | 1978-05-02 | Gte Laboratories, Incorporated | Reactivation of primary electrochemical cells |
AU633612B2 (en) * | 1989-08-25 | 1993-02-04 | Warner-Lambert Company | Improved process for cyclic amino acid anticonvulsant compounds |
-
1988
- 1988-05-02 US US07/188,819 patent/US4894476A/en not_active Expired - Lifetime
-
1989
- 1989-04-10 IE IE114289A patent/IE62958B1/en not_active IP Right Cessation
- 1989-04-11 AU AU32678/89A patent/AU624130B2/en not_active Expired
- 1989-04-11 CA CA000596341A patent/CA1306755C/en not_active Expired - Fee Related
- 1989-04-28 FI FI892067A patent/FI892067A/fi not_active IP Right Cessation
- 1989-04-28 ES ES89107795T patent/ES2061774T3/es not_active Expired - Lifetime
- 1989-04-28 AT AT89107795T patent/ATE101116T1/de not_active IP Right Cessation
- 1989-04-28 DE DE68912819T patent/DE68912819T2/de not_active Expired - Lifetime
- 1989-04-28 EP EP89107795A patent/EP0340677B1/en not_active Expired - Lifetime
- 1989-05-01 DK DK198902126A patent/DK175400B1/da not_active IP Right Cessation
- 1989-05-01 JP JP1109264A patent/JP2619951B2/ja not_active Expired - Fee Related
-
1997
- 1997-12-10 HK HK97102376A patent/HK1000798A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU624130B2 (en) | 1992-06-04 |
DE68912819T2 (de) | 1994-05-19 |
US4894476A (en) | 1990-01-16 |
EP0340677B1 (en) | 1994-02-02 |
DE68912819D1 (de) | 1994-03-17 |
JP2619951B2 (ja) | 1997-06-11 |
HK1000798A1 (en) | 1998-05-01 |
DK175400B1 (da) | 2004-09-27 |
FI892067A (fi) | 1989-11-03 |
JPH0211546A (ja) | 1990-01-16 |
IE62958B1 (en) | 1995-03-08 |
EP0340677A2 (en) | 1989-11-08 |
ATE101116T1 (de) | 1994-02-15 |
DK212689D0 (da) | 1989-05-01 |
ES2061774T3 (es) | 1994-12-16 |
IE891142L (en) | 1989-11-02 |
AU3267889A (en) | 1989-11-02 |
EP0340677A3 (en) | 1990-12-27 |
FI892067A0 (fi) | 1989-04-28 |
CA1306755C (en) | 1992-08-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |