HK1000768A1 - Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities - Google Patents
Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activitiesInfo
- Publication number
- HK1000768A1 HK1000768A1 HK97102319A HK97102319A HK1000768A1 HK 1000768 A1 HK1000768 A1 HK 1000768A1 HK 97102319 A HK97102319 A HK 97102319A HK 97102319 A HK97102319 A HK 97102319A HK 1000768 A1 HK1000768 A1 HK 1000768A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- optionally substituted
- acyl
- halogen
- substituted
- sympathomimetic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/14—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929202236A GB9202236D0 (en) | 1992-02-03 | 1992-02-03 | New ethanolamine derivatives,a process for the preparation thereof and pharmaceutical composition comprising the same |
GB929217991A GB9217991D0 (en) | 1992-08-24 | 1992-08-24 | New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same |
PCT/JP1993/000113 WO1993015041A1 (en) | 1992-02-03 | 1993-02-01 | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1000768A1 true HK1000768A1 (en) | 1998-04-24 |
Family
ID=26300256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK97102319A HK1000768A1 (en) | 1992-02-03 | 1997-12-03 | Ethanolamine derivatives having sympathomimetic and anti-pollakiuria activities |
Country Status (19)
Country | Link |
---|---|
US (1) | US5387710A (da) |
EP (1) | EP0583485B1 (da) |
JP (2) | JP2819435B2 (da) |
KR (1) | KR100250922B1 (da) |
CN (1) | CN1063430C (da) |
AT (1) | ATE156804T1 (da) |
AU (1) | AU666162B2 (da) |
CA (1) | CA2107566A1 (da) |
DE (1) | DE69313051T2 (da) |
DK (1) | DK0583485T3 (da) |
ES (1) | ES2105286T3 (da) |
GR (1) | GR3025106T3 (da) |
HK (1) | HK1000768A1 (da) |
HU (1) | HU218941B (da) |
IL (1) | IL104567A (da) |
MX (1) | MX9300552A (da) |
TW (1) | TW225513B (da) |
UA (1) | UA41869C2 (da) |
WO (1) | WO1993015041A1 (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9608332A (pt) * | 1995-04-15 | 1999-02-23 | Dainippon Pharmaceutical Co | Derivados de 1-(w-Ú3,4-dihidro-2-naftalenil)aquil¾ amina cíclica processo para a preparaç o dos mesmos e composiç o farmacêutica contendo os mesmos |
TW375604B (en) * | 1996-02-19 | 1999-12-01 | Kissei Pharmaceutical | 3,4-di-substituting phenyl-ethanolamine-tetrahydronaphthyl carboxylic amide derivatives |
WO1998007445A1 (fr) | 1996-08-19 | 1998-02-26 | Kissei Pharmaceutical Co., Ltd. | Remede therapeutique ou preventif contre l'incontinence ou l'elimination urinaire frequente |
AUPO565997A0 (en) | 1997-03-17 | 1997-04-10 | Fujisawa Pharmaceutical Co., Ltd. | Propanolamine derivatives |
GB9913083D0 (en) | 1999-06-04 | 1999-08-04 | Novartis Ag | Organic compounds |
WO2003035600A1 (fr) * | 2001-10-19 | 2003-05-01 | Fujisawa Pharmaceutical Co., Ltd. | Procede de production de derive de benzocycloheptene |
WO2003043655A1 (fr) * | 2001-11-19 | 2003-05-30 | Ono Pharmaceutical Co., Ltd. | Remedes pour la frequence urinaire |
US20050090669A1 (en) * | 2002-03-14 | 2005-04-28 | Kouji Hattori | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists |
ES2360353T3 (es) | 2002-11-07 | 2011-06-03 | Astellas Pharma Inc. | Acción correctora para hiperactividad de vejiga urinaria que comprende un derivado de anilida de ácido acético como principio activo. |
EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
ES2437323T3 (es) | 2007-02-16 | 2014-01-10 | Ono Pharmaceutical Co., Ltd. | Agente terapéutico para trastornos de la micción |
EP2544534A4 (en) * | 2010-03-08 | 2015-05-13 | Medicinova Inc | COMPOSITIONS, METHODS AND DEVICES USED IN THE TREATMENT OF DYSMENORRHEA |
KR20130040862A (ko) * | 2010-04-08 | 2013-04-24 | 메디시노바, 인크. | 과민성 대장 증후군의 치료를 위한 방법 및 조성물 |
US20120309796A1 (en) * | 2011-06-06 | 2012-12-06 | Fariborz Firooznia | Benzocycloheptene acetic acids |
WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
CN111233820B (zh) * | 2018-11-29 | 2022-11-18 | 睿阜隆(杭州)生物医药有限公司 | 含有冠醚和二(2-甲氧基乙氧基)结构的芬戈莫德衍生物 |
CA3218884A1 (en) * | 2021-05-11 | 2022-11-17 | David Nutt | Therapeutic aminoindane compounds and compositions |
GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL79323A (en) * | 1985-07-10 | 1990-03-19 | Sanofi Sa | Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them |
IT1199339B (it) * | 1986-12-23 | 1988-12-30 | Sigma Tau Ind Farmaceuti | N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono |
FR2643076B1 (fr) * | 1989-02-14 | 1991-06-21 | Midy Spa | Carboxyalkyl-ethers de la 2-amino-7-hydroxytetraline |
EP0499755A1 (fr) * | 1991-02-18 | 1992-08-26 | MIDY S.p.A. | Nouvelles phényléthanolaminotétralines, procédé pour leur préparation, intermédiaires dans ce procédé et compositions pharmaceutiques les contenant |
-
1993
- 1993-01-31 IL IL104567A patent/IL104567A/xx not_active IP Right Cessation
- 1993-02-01 JP JP5513097A patent/JP2819435B2/ja not_active Expired - Fee Related
- 1993-02-01 DK DK93914517.3T patent/DK0583485T3/da active
- 1993-02-01 DE DE69313051T patent/DE69313051T2/de not_active Expired - Fee Related
- 1993-02-01 EP EP93914517A patent/EP0583485B1/en not_active Expired - Lifetime
- 1993-02-01 HU HU9303112A patent/HU218941B/hu not_active IP Right Cessation
- 1993-02-01 UA UA93003971A patent/UA41869C2/uk unknown
- 1993-02-01 TW TW082100626A patent/TW225513B/zh active
- 1993-02-01 WO PCT/JP1993/000113 patent/WO1993015041A1/en active IP Right Grant
- 1993-02-01 ES ES93914517T patent/ES2105286T3/es not_active Expired - Lifetime
- 1993-02-01 AT AT93914517T patent/ATE156804T1/de not_active IP Right Cessation
- 1993-02-01 AU AU33679/93A patent/AU666162B2/en not_active Ceased
- 1993-02-01 CA CA002107566A patent/CA2107566A1/en not_active Abandoned
- 1993-02-01 KR KR1019930702932A patent/KR100250922B1/ko not_active IP Right Cessation
- 1993-02-02 CN CN93102681A patent/CN1063430C/zh not_active Expired - Fee Related
- 1993-02-02 MX MX9300552A patent/MX9300552A/es not_active IP Right Cessation
- 1993-09-17 US US08/117,163 patent/US5387710A/en not_active Expired - Lifetime
-
1997
- 1997-10-21 GR GR970402748T patent/GR3025106T3/el unknown
- 1997-12-03 HK HK97102319A patent/HK1000768A1/xx not_active IP Right Cessation
-
1998
- 1998-05-13 JP JP13016798A patent/JP3282799B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69313051D1 (de) | 1997-09-18 |
DE69313051T2 (de) | 1998-01-08 |
DK0583485T3 (da) | 1997-10-06 |
MX9300552A (es) | 1993-09-01 |
HU9303112D0 (en) | 1994-01-28 |
TW225513B (da) | 1994-06-21 |
HU218941B (hu) | 2001-01-29 |
EP0583485A1 (en) | 1994-02-23 |
CN1084846A (zh) | 1994-04-06 |
EP0583485B1 (en) | 1997-08-13 |
CA2107566A1 (en) | 1993-08-04 |
JP3282799B2 (ja) | 2002-05-20 |
CN1063430C (zh) | 2001-03-21 |
JPH06506955A (ja) | 1994-08-04 |
JP2819435B2 (ja) | 1998-10-30 |
ATE156804T1 (de) | 1997-08-15 |
ES2105286T3 (es) | 1997-10-16 |
GR3025106T3 (en) | 1998-01-30 |
AU666162B2 (en) | 1996-02-01 |
JPH1192432A (ja) | 1999-04-06 |
US5387710A (en) | 1995-02-07 |
IL104567A0 (en) | 1993-05-13 |
UA41869C2 (uk) | 2001-10-15 |
AU3367993A (en) | 1993-09-01 |
HUT65351A (en) | 1994-05-02 |
IL104567A (en) | 1997-03-18 |
WO1993015041A1 (en) | 1993-08-05 |
KR100250922B1 (ko) | 2000-05-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW225513B (da) | ||
AU2337097A (en) | Meta-substituted phenylene derivatives and their use as alphavbeta3 integrin antagonists or inhibitors | |
GR3036887T3 (en) | Meta-substituted phenylene sulphonamide derivatives | |
AU6052594A (en) | New heterocyclic compounds | |
IL108562A0 (en) | Heterocyclic compounds, processes for the preparation thereof, and pharmaceutical compositions containing them | |
BG100946A (en) | New amino acid derivatives, method for their preparation and pharmaceutical compositions containing them | |
DE69130412D1 (de) | Pyrazolopyridinverbindung und Verfahren zu ihrer Herstellung | |
DE3854454D1 (de) | Pyrazolopyridinverbindungen und Verfahren zu ihrer Herstellung. | |
GB9107827D0 (en) | New ethanolamine derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same | |
GB9602029D0 (en) | New heterocyclic compounds | |
IL108969A0 (en) | Substituted (arylalkoxybenzyl) aminopropionamide derivatives, their preparation and pharmaceutical compositions containing them | |
GB9426090D0 (en) | Pharmaceutical compounds | |
IL108970A0 (en) | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives, their preparation and pharmaceutical compositions containing them | |
DE69330601D1 (de) | Serotoninergische ergolin derivate | |
ES2122521T3 (es) | Derivados de 2'-desoxi-5-fluorouridina y sus sales farmaceuticamente aceptables, procedimiento para su preparacion y agentes antitumorales. | |
TW289019B (da) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20040201 |
|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |