GT200600432A - Compuestos de amino-5-[4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de la beta-secretasa - Google Patents

Compuestos de amino-5-[4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de la beta-secretasa

Info

Publication number
GT200600432A
GT200600432A GT200600432A GT200600432A GT200600432A GT 200600432 A GT200600432 A GT 200600432A GT 200600432 A GT200600432 A GT 200600432A GT 200600432 A GT200600432 A GT 200600432A GT 200600432 A GT200600432 A GT 200600432A
Authority
GT
Guatemala
Prior art keywords
beta
compounds
difluorometoxi
phenyl
amino
Prior art date
Application number
GT200600432A
Other languages
English (en)
Spanish (es)
Inventor
Michael Sotirios Malamas
James Joseph Erdei
William Floyd Fobare
Dominick Anthony Quagliato
Schuyler Adam Antane
Albert Jean Rochibaud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200600432A publication Critical patent/GT200600432A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GT200600432A 2005-09-26 2006-09-26 Compuestos de amino-5-[4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de la beta-secretasa GT200600432A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72058905P 2005-09-26 2005-09-26

Publications (1)

Publication Number Publication Date
GT200600432A true GT200600432A (es) 2007-05-28

Family

ID=37693581

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200600432A GT200600432A (es) 2005-09-26 2006-09-26 Compuestos de amino-5-[4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de la beta-secretasa

Country Status (19)

Country Link
US (2) US7423158B2 (zh)
EP (2) EP2256107A1 (zh)
JP (1) JP2009509957A (zh)
KR (1) KR20080050430A (zh)
CN (1) CN101273018A (zh)
AR (1) AR056536A1 (zh)
AU (1) AU2006294620A1 (zh)
BR (1) BRPI0616757A2 (zh)
CA (1) CA2623245A1 (zh)
CR (1) CR9830A (zh)
EC (1) ECSP088286A (zh)
GT (1) GT200600432A (zh)
IL (1) IL189650A0 (zh)
NO (1) NO20080942L (zh)
PE (1) PE20070461A1 (zh)
RU (1) RU2008106936A (zh)
TW (1) TW200808735A (zh)
WO (1) WO2007038271A1 (zh)
ZA (1) ZA200802636B (zh)

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Also Published As

Publication number Publication date
BRPI0616757A2 (pt) 2011-06-28
KR20080050430A (ko) 2008-06-05
EP2256107A1 (en) 2010-12-01
CA2623245A1 (en) 2007-04-05
PE20070461A1 (es) 2007-05-10
US20090012139A1 (en) 2009-01-08
WO2007038271A9 (en) 2008-05-08
JP2009509957A (ja) 2009-03-12
EP1928841A1 (en) 2008-06-11
WO2007038271A1 (en) 2007-04-05
CN101273018A (zh) 2008-09-24
TW200808735A (en) 2008-02-16
RU2008106936A (ru) 2009-11-10
US7423158B2 (en) 2008-09-09
CR9830A (es) 2008-05-21
US20070072925A1 (en) 2007-03-29
IL189650A0 (en) 2008-06-05
AU2006294620A1 (en) 2007-04-05
AR056536A1 (es) 2007-10-10
NO20080942L (no) 2008-04-07
ZA200802636B (en) 2009-03-25
ECSP088286A (es) 2008-04-28

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