GR870662B - Process for preparing 1,4 - disubstituted piperazine derivatives and pharmaceutical compositions containing them - Google Patents
Process for preparing 1,4 - disubstituted piperazine derivatives and pharmaceutical compositions containing themInfo
- Publication number
- GR870662B GR870662B GR870662A GR870100662A GR870662B GR 870662 B GR870662 B GR 870662B GR 870662 A GR870662 A GR 870662A GR 870100662 A GR870100662 A GR 870100662A GR 870662 B GR870662 B GR 870662B
- Authority
- GR
- Greece
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- piperazine derivatives
- general formula
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU861750A HU196195B (en) | 1986-04-28 | 1986-04-28 | Process for producing 1,4-disubstituted piperazine derivatives and pharmaceuticals comprising the compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GR870662B true GR870662B (en) | 1987-09-02 |
Family
ID=10956006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR870662A GR870662B (en) | 1986-04-28 | 1987-04-28 | Process for preparing 1,4 - disubstituted piperazine derivatives and pharmaceutical compositions containing them |
Country Status (14)
Country | Link |
---|---|
US (1) | US4866062A (el) |
EP (1) | EP0243904B1 (el) |
JP (1) | JPS62294674A (el) |
AT (1) | ATE57922T1 (el) |
AU (1) | AU595026B2 (el) |
CA (1) | CA1277986C (el) |
DE (1) | DE3765827D1 (el) |
DK (1) | DK213087A (el) |
ES (1) | ES2004409A6 (el) |
FI (1) | FI85267C (el) |
GR (1) | GR870662B (el) |
HU (1) | HU196195B (el) |
IL (1) | IL82358A (el) |
ZA (1) | ZA873028B (el) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU196196B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing new benzhydryl-piperazine derivatives and pharmaceuticals comprising the compounds |
ATE81651T1 (de) * | 1988-10-10 | 1992-11-15 | Akzo Nv | Substituierte aromatische verbindungen mit zentraler nervensystem-wirkung. |
WO1991009594A1 (en) * | 1989-12-28 | 1991-07-11 | Virginia Commonwealth University | Sigma receptor ligands and the use thereof |
US5276035A (en) * | 1990-07-26 | 1994-01-04 | Novo Nordisk A/S | 1,4-disubstituted piperazines |
DK178490D0 (da) * | 1990-07-26 | 1990-07-26 | Novo Nordisk As | 1,4-disubstituerede piperaziner |
US5252586A (en) * | 1990-09-28 | 1993-10-12 | The Du Pont Merck Pharmaceutical Company | Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents |
FR2673182A1 (fr) * | 1991-02-22 | 1992-08-28 | Univ Caen | Piperazines n,n'-disubstituees, leur procede de preparation et leur application en therapeutique. |
WO1993000811A1 (en) * | 1991-07-01 | 1993-01-21 | The General Hospital Corporation | Invertebrate phenylethanolamine transporter and the use thereof |
ZA944513B (en) * | 1993-06-23 | 1996-01-16 | Cambridge Neuroscience Inc | Sigma receptor ligands |
US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
US6756389B2 (en) * | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6799637B2 (en) | 2000-10-20 | 2004-10-05 | Schlumberger Technology Corporation | Expandable tubing and method |
NO335594B1 (no) | 2001-01-16 | 2015-01-12 | Halliburton Energy Serv Inc | Ekspanderbare anordninger og fremgangsmåte for disse |
US8404330B2 (en) * | 2004-08-23 | 2013-03-26 | E I Du Pont De Nemours And Company | Breathable low-emissivity metallized sheets |
US8216600B2 (en) * | 2007-11-14 | 2012-07-10 | Cordis Corporation | Polymeric materials for medical devices |
WO2014138518A2 (en) | 2013-03-08 | 2014-09-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof |
EP3157408A4 (en) | 2014-06-17 | 2018-03-07 | Ganiban, Gary | Devices and methods to provide hands free scleral depression during ophthalmic procedures |
US11365195B2 (en) | 2017-11-13 | 2022-06-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Atypical inhibitors of monoamine transporters; method of making; and use thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE530797A (el) * | ||||
BE530796A (el) * | ||||
BE530795A (el) * | ||||
US2988551A (en) * | 1954-07-30 | 1961-06-13 | Union Chimique Belge Sa | Piperazine derivatives |
CH396007A (fr) * | 1961-06-12 | 1965-07-31 | Pharma Yptor S A Lab | Procédé de fabrication de nouveaux dérivés de la pipérazine |
GB1545094A (en) * | 1976-12-14 | 1979-05-02 | Gist Brocades Nv | Piperazine derivatives |
NL8202636A (nl) * | 1982-06-29 | 1984-01-16 | Gist Brocades Nv | Piperazinederivaten, werkwijzen ter bereiding daarvan en farmaceutische preparaten die deze verbindingen bevatten. |
HU196196B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing new benzhydryl-piperazine derivatives and pharmaceuticals comprising the compounds |
-
1986
- 1986-04-28 HU HU861750A patent/HU196195B/hu not_active IP Right Cessation
-
1987
- 1987-04-22 US US07/041,234 patent/US4866062A/en not_active Expired - Fee Related
- 1987-04-27 DK DK213087A patent/DK213087A/da not_active Application Discontinuation
- 1987-04-28 DE DE8787106033T patent/DE3765827D1/de not_active Expired - Fee Related
- 1987-04-28 ES ES8701261A patent/ES2004409A6/es not_active Expired
- 1987-04-28 IL IL82358A patent/IL82358A/xx unknown
- 1987-04-28 FI FI871875A patent/FI85267C/fi not_active IP Right Cessation
- 1987-04-28 GR GR870662A patent/GR870662B/el unknown
- 1987-04-28 ZA ZA873028A patent/ZA873028B/xx unknown
- 1987-04-28 CA CA000535730A patent/CA1277986C/en not_active Expired - Fee Related
- 1987-04-28 JP JP62106157A patent/JPS62294674A/ja active Pending
- 1987-04-28 EP EP87106033A patent/EP0243904B1/de not_active Expired - Lifetime
- 1987-04-28 AU AU72159/87A patent/AU595026B2/en not_active Ceased
- 1987-04-28 AT AT87106033T patent/ATE57922T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4866062A (en) | 1989-09-12 |
CA1277986C (en) | 1990-12-18 |
DK213087A (da) | 1987-10-29 |
FI85267B (fi) | 1991-12-13 |
EP0243904B1 (de) | 1990-10-31 |
FI85267C (fi) | 1992-03-25 |
HU196195B (en) | 1988-10-28 |
HUT45038A (en) | 1988-05-30 |
ATE57922T1 (de) | 1990-11-15 |
AU7215987A (en) | 1987-10-29 |
ZA873028B (en) | 1987-10-21 |
EP0243904A1 (de) | 1987-11-04 |
AU595026B2 (en) | 1990-03-22 |
IL82358A0 (en) | 1987-10-30 |
ES2004409A6 (es) | 1989-01-01 |
IL82358A (en) | 1991-03-10 |
FI871875A (fi) | 1987-10-29 |
DE3765827D1 (de) | 1990-12-06 |
DK213087D0 (da) | 1987-04-27 |
FI871875A0 (fi) | 1987-04-28 |
JPS62294674A (ja) | 1987-12-22 |
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