GR78453B - - Google Patents
Info
- Publication number
- GR78453B GR78453B GR70765A GR830170765A GR78453B GR 78453 B GR78453 B GR 78453B GR 70765 A GR70765 A GR 70765A GR 830170765 A GR830170765 A GR 830170765A GR 78453 B GR78453 B GR 78453B
- Authority
- GR
- Greece
- Prior art keywords
- insulins
- trypsin
- analogs
- ester
- preproinsulins
- Prior art date
Links
- 108090001061 Insulin Proteins 0.000 abstract 2
- 102000004877 Insulin Human genes 0.000 abstract 2
- 239000004026 insulin derivative Substances 0.000 abstract 2
- 102000005593 Endopeptidases Human genes 0.000 abstract 1
- 108010059378 Endopeptidases Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 108010066381 preproinsulin Proteins 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
- 230000001810 trypsinlike Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823209184 DE3209184A1 (de) | 1982-03-13 | 1982-03-13 | Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR78453B true GR78453B (enEXAMPLES) | 1984-09-27 |
Family
ID=6158163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR70765A GR78453B (enEXAMPLES) | 1982-03-13 | 1983-03-11 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4639333A (enEXAMPLES) |
| EP (1) | EP0089007B1 (enEXAMPLES) |
| JP (1) | JPS58190398A (enEXAMPLES) |
| KR (1) | KR900003502B1 (enEXAMPLES) |
| AT (1) | ATE21118T1 (enEXAMPLES) |
| AU (1) | AU553832B2 (enEXAMPLES) |
| CA (1) | CA1195273A (enEXAMPLES) |
| DE (2) | DE3209184A1 (enEXAMPLES) |
| DK (1) | DK154573C (enEXAMPLES) |
| ES (1) | ES520493A0 (enEXAMPLES) |
| FI (1) | FI79117C (enEXAMPLES) |
| GR (1) | GR78453B (enEXAMPLES) |
| IE (1) | IE54605B1 (enEXAMPLES) |
| IL (1) | IL68103A (enEXAMPLES) |
| ZA (1) | ZA831693B (enEXAMPLES) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3326472A1 (de) * | 1983-07-22 | 1985-02-14 | Hoechst Ag, 6230 Frankfurt | Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus |
| DE3333640A1 (de) * | 1983-09-17 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung |
| US4569791A (en) * | 1984-06-14 | 1986-02-11 | Eli Lilly And Company | Anti-diabetic compounds |
| US4569792A (en) * | 1984-06-14 | 1986-02-11 | Eli Lilly And Company | Anti-diabetic compounds |
| US4581165A (en) * | 1984-06-14 | 1986-04-08 | Eli Lilly And Company | Anti-diabetic compounds |
| DK129385A (da) * | 1985-03-22 | 1986-09-23 | Novo Industri As | Peptider og fremstilling deraf |
| CA1339416C (en) * | 1987-02-25 | 1997-09-02 | Liselotte Langkjaer | Insulin derivatives |
| US5514646A (en) * | 1989-02-09 | 1996-05-07 | Chance; Ronald E. | Insulin analogs modified at position 29 of the B chain |
| CZ283234B6 (cs) * | 1990-09-05 | 1998-02-18 | Hoechst Aktiengesellschaft | Enymatický způsob konverse preproinsulinů na insuliny |
| DK2307441T3 (da) | 2008-08-07 | 2016-05-23 | Biocon Ltd | Fremgangsmåde til fremstilling af insulinforbindelser |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3276961A (en) * | 1963-04-08 | 1966-10-04 | Squibb & Sons Inc | Process for preparing human insulin |
| GB1426061A (en) * | 1972-12-28 | 1976-02-25 | Ici Ltd | Polypeptides |
| US3903068A (en) * | 1972-12-26 | 1975-09-02 | Us Health Education & Welfare | Facile synthesis of human insulin by modification of porcine insulin |
| NO153061C (no) * | 1979-04-13 | 1986-01-08 | Shionogi & Co | Fremgangsmaate for fremstilling av et b30-threonininsulin |
| JPS55138393A (en) * | 1979-04-13 | 1980-10-29 | Shionogi & Co Ltd | Semisynthesis of insulin |
| DK147437A (en) * | 1980-02-11 | 1900-01-01 | Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof | |
| ZA811972B (en) * | 1980-03-27 | 1982-11-24 | Lilly Co Eli | Process for producing an insulin precursor |
| DK319780A (da) * | 1980-07-24 | 1982-01-25 | Forenede Bryggerier As | Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner |
| DE3101382A1 (de) * | 1981-01-17 | 1982-09-02 | Hoechst Ag, 6000 Frankfurt | "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten" |
-
1982
- 1982-03-13 DE DE19823209184 patent/DE3209184A1/de not_active Withdrawn
-
1983
- 1983-03-10 IL IL68103A patent/IL68103A/xx not_active IP Right Cessation
- 1983-03-10 EP EP83102337A patent/EP0089007B1/de not_active Expired
- 1983-03-10 DE DE8383102337T patent/DE3364838D1/de not_active Expired
- 1983-03-10 FI FI830813A patent/FI79117C/fi not_active IP Right Cessation
- 1983-03-10 AT AT83102337T patent/ATE21118T1/de not_active IP Right Cessation
- 1983-03-11 ZA ZA831693A patent/ZA831693B/xx unknown
- 1983-03-11 DK DK117883A patent/DK154573C/da not_active IP Right Cessation
- 1983-03-11 ES ES520493A patent/ES520493A0/es active Granted
- 1983-03-11 JP JP58039298A patent/JPS58190398A/ja active Granted
- 1983-03-11 GR GR70765A patent/GR78453B/el unknown
- 1983-03-11 KR KR1019830000978A patent/KR900003502B1/ko not_active Expired
- 1983-03-11 CA CA000423391A patent/CA1195273A/en not_active Expired
- 1983-03-11 IE IE529/83A patent/IE54605B1/en not_active IP Right Cessation
- 1983-03-11 AU AU12428/83A patent/AU553832B2/en not_active Ceased
-
1984
- 1984-10-12 US US06/659,865 patent/US4639333A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IE830529L (en) | 1983-09-13 |
| FI79117B (fi) | 1989-07-31 |
| KR840004169A (ko) | 1984-10-10 |
| DK117883D0 (da) | 1983-03-11 |
| DK117883A (da) | 1983-09-14 |
| FI830813L (fi) | 1983-09-14 |
| JPH0536034B2 (enEXAMPLES) | 1993-05-28 |
| EP0089007A1 (de) | 1983-09-21 |
| JPS58190398A (ja) | 1983-11-07 |
| DK154573C (da) | 1989-05-22 |
| IE54605B1 (en) | 1989-12-06 |
| ATE21118T1 (de) | 1986-08-15 |
| ZA831693B (en) | 1983-11-30 |
| ES8401448A1 (es) | 1983-12-16 |
| AU1242883A (en) | 1983-09-15 |
| IL68103A0 (en) | 1983-06-15 |
| EP0089007B1 (de) | 1986-07-30 |
| DK154573B (da) | 1988-11-28 |
| AU553832B2 (en) | 1986-07-31 |
| CA1195273A (en) | 1985-10-15 |
| DE3209184A1 (de) | 1983-09-15 |
| IL68103A (en) | 1986-01-31 |
| KR900003502B1 (ko) | 1990-05-21 |
| DE3364838D1 (en) | 1986-09-04 |
| FI79117C (fi) | 1989-11-10 |
| ES520493A0 (es) | 1983-12-16 |
| US4639333A (en) | 1987-01-27 |
| FI830813A0 (fi) | 1983-03-10 |
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