GR3035752T3 - Process for the preparation of galanthamine and its derivatives - Google Patents

Process for the preparation of galanthamine and its derivatives

Info

Publication number
GR3035752T3
GR3035752T3 GR20010400603T GR20010400603T GR3035752T3 GR 3035752 T3 GR3035752 T3 GR 3035752T3 GR 20010400603 T GR20010400603 T GR 20010400603T GR 20010400603 T GR20010400603 T GR 20010400603T GR 3035752 T3 GR3035752 T3 GR 3035752T3
Authority
GR
Greece
Prior art keywords
crushed
compound
galanthamine
derivatives
preparation
Prior art date
Application number
GR20010400603T
Other languages
English (en)
Inventor
Robin Mark Bannister
Raymond Mccague
Original Assignee
Chiroscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd
Publication of GR3035752T3 publication Critical patent/GR3035752T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GR20010400603T 1995-09-21 2001-04-12 Process for the preparation of galanthamine and its derivatives GR3035752T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9519268.8A GB9519268D0 (en) 1995-09-21 1995-09-21 Preparation of alkaloids
PCT/GB1996/002335 WO1997011078A1 (en) 1995-09-21 1996-09-23 Process for the preparation of galanthamine and its derivatives

Publications (1)

Publication Number Publication Date
GR3035752T3 true GR3035752T3 (en) 2001-07-31

Family

ID=10781039

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400603T GR3035752T3 (en) 1995-09-21 2001-04-12 Process for the preparation of galanthamine and its derivatives

Country Status (12)

Country Link
US (1) US6184004B1 (el)
EP (1) EP0853624B1 (el)
AT (1) ATE199153T1 (el)
AU (1) AU710980B2 (el)
CA (1) CA2230824C (el)
DE (1) DE69611796T2 (el)
DK (1) DK0853624T3 (el)
ES (1) ES2155200T3 (el)
GB (1) GB9519268D0 (el)
GR (1) GR3035752T3 (el)
PT (1) PT853624E (el)
WO (1) WO1997011078A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT403803B (de) 1996-04-19 1998-05-25 Sanochemia Ltd Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
EP1181294B1 (de) 2000-03-31 2004-03-31 Sanochemia Pharmazeutika Aktiengesellschaft Neue derivate und analoga von galanthamin
JP4029960B2 (ja) * 2001-10-05 2008-01-09 独立行政法人理化学研究所 アブシジン酸生合成阻害剤
WO2005065662A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
WO2005065661A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galanthamine
EP2316437B1 (en) * 2005-05-13 2014-07-30 Alza Corporation Multilayer drug delivery system with barrier against reservoir material flow
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
AT504663B1 (de) * 2007-02-22 2008-07-15 Sanochemia Pharmazeutika Ag Verfahren zum herstellen von hochreinen 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- f)(2) benzazepinen sowie dessen derivaten
CN104592243B (zh) * 2014-12-19 2016-08-24 北京大学 加兰他敏和力克拉敏的不对称合成方法
BG67337B1 (bg) 2018-05-23 2021-06-15 Софарма Ад Метод за получаване на пречистен галантамин хидробромид

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4290862A (en) * 1979-11-14 1981-09-22 Edinen Centar P Chimia Method for the preparation of narwedine-type enones
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
US5428159A (en) * 1994-04-08 1995-06-27 Ciba-Geigy Corporation Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

Also Published As

Publication number Publication date
DK0853624T3 (da) 2001-05-07
PT853624E (pt) 2001-06-29
DE69611796T2 (de) 2001-10-11
WO1997011078A1 (en) 1997-03-27
US6184004B1 (en) 2001-02-06
ES2155200T3 (es) 2001-05-01
AU6996596A (en) 1997-04-09
ATE199153T1 (de) 2001-02-15
CA2230824A1 (en) 1997-03-27
DE69611796D1 (de) 2001-03-22
CA2230824C (en) 2009-09-15
GB9519268D0 (en) 1995-11-22
EP0853624B1 (en) 2001-02-14
AU710980B2 (en) 1999-10-07
EP0853624A1 (en) 1998-07-22

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