ES2155200T3 - Proceso para la preparacion de galantamina y sus derivados. - Google Patents
Proceso para la preparacion de galantamina y sus derivados.Info
- Publication number
- ES2155200T3 ES2155200T3 ES96931170T ES96931170T ES2155200T3 ES 2155200 T3 ES2155200 T3 ES 2155200T3 ES 96931170 T ES96931170 T ES 96931170T ES 96931170 T ES96931170 T ES 96931170T ES 2155200 T3 ES2155200 T3 ES 2155200T3
- Authority
- ES
- Spain
- Prior art keywords
- crushed
- compound
- galantamine
- derivatives
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE UN COMPUESTO DE FORMULA (4) O (5), BIEN EN FORMA OPTICAMENTE ENRIQUECIDA O BIEN RACEMICA, SIENDO SELECCIONADOS R 1 , R 2 , R 3 Y R 4 INDEPENDIENTEMENTE A PARTIR DE HIDROGENO, O DE GRUPOS ALQUILO, ARILO, ALCARILO, ARALQUILO Y ACILO. DICHO PROCEDIMIENTO CONSISTE EN MEZCLAR UN PRECURSOR DE CICLACION OXIDATIVA DEL COMPUESTO CITADO CON EL EXTRACTO DE UNA PLANTA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9519268.8A GB9519268D0 (en) | 1995-09-21 | 1995-09-21 | Preparation of alkaloids |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2155200T3 true ES2155200T3 (es) | 2001-05-01 |
Family
ID=10781039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96931170T Expired - Lifetime ES2155200T3 (es) | 1995-09-21 | 1996-09-23 | Proceso para la preparacion de galantamina y sus derivados. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6184004B1 (es) |
EP (1) | EP0853624B1 (es) |
AT (1) | ATE199153T1 (es) |
AU (1) | AU710980B2 (es) |
CA (1) | CA2230824C (es) |
DE (1) | DE69611796T2 (es) |
DK (1) | DK0853624T3 (es) |
ES (1) | ES2155200T3 (es) |
GB (1) | GB9519268D0 (es) |
GR (1) | GR3035752T3 (es) |
PT (1) | PT853624E (es) |
WO (1) | WO1997011078A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT403803B (de) | 1996-04-19 | 1998-05-25 | Sanochemia Ltd | Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln |
EP1181294B1 (de) | 2000-03-31 | 2004-03-31 | Sanochemia Pharmazeutika Aktiengesellschaft | Neue derivate und analoga von galanthamin |
JP4029960B2 (ja) * | 2001-10-05 | 2008-01-09 | 独立行政法人理化学研究所 | アブシジン酸生合成阻害剤 |
WO2005065662A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Solid dosage formulations of galantamine |
WO2005065661A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Immediate, controlled and sustained release formulations of galanthamine |
EP2316437B1 (en) * | 2005-05-13 | 2014-07-30 | Alza Corporation | Multilayer drug delivery system with barrier against reservoir material flow |
WO2007035941A2 (en) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Transdermal galantamine delivery system |
AT504663B1 (de) * | 2007-02-22 | 2008-07-15 | Sanochemia Pharmazeutika Ag | Verfahren zum herstellen von hochreinen 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- f)(2) benzazepinen sowie dessen derivaten |
CN104592243B (zh) * | 2014-12-19 | 2016-08-24 | 北京大学 | 加兰他敏和力克拉敏的不对称合成方法 |
BG67337B1 (bg) | 2018-05-23 | 2021-06-15 | Софарма Ад | Метод за получаване на пречистен галантамин хидробромид |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4290862A (en) * | 1979-11-14 | 1981-09-22 | Edinen Centar P Chimia | Method for the preparation of narwedine-type enones |
US5336675A (en) * | 1991-05-14 | 1994-08-09 | Ernir Snorrason | Method of treating mania in humans |
US5428159A (en) * | 1994-04-08 | 1995-06-27 | Ciba-Geigy Corporation | Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine |
-
1995
- 1995-09-21 GB GBGB9519268.8A patent/GB9519268D0/en active Pending
-
1996
- 1996-09-23 DK DK96931170T patent/DK0853624T3/da active
- 1996-09-23 US US09/043,598 patent/US6184004B1/en not_active Expired - Lifetime
- 1996-09-23 WO PCT/GB1996/002335 patent/WO1997011078A1/en active IP Right Grant
- 1996-09-23 AT AT96931170T patent/ATE199153T1/de active
- 1996-09-23 CA CA002230824A patent/CA2230824C/en not_active Expired - Lifetime
- 1996-09-23 PT PT96931170T patent/PT853624E/pt unknown
- 1996-09-23 AU AU69965/96A patent/AU710980B2/en not_active Expired
- 1996-09-23 EP EP96931170A patent/EP0853624B1/en not_active Expired - Lifetime
- 1996-09-23 ES ES96931170T patent/ES2155200T3/es not_active Expired - Lifetime
- 1996-09-23 DE DE69611796T patent/DE69611796T2/de not_active Expired - Lifetime
-
2001
- 2001-04-12 GR GR20010400603T patent/GR3035752T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0853624T3 (da) | 2001-05-07 |
PT853624E (pt) | 2001-06-29 |
DE69611796T2 (de) | 2001-10-11 |
WO1997011078A1 (en) | 1997-03-27 |
US6184004B1 (en) | 2001-02-06 |
GR3035752T3 (en) | 2001-07-31 |
AU6996596A (en) | 1997-04-09 |
ATE199153T1 (de) | 2001-02-15 |
CA2230824A1 (en) | 1997-03-27 |
DE69611796D1 (de) | 2001-03-22 |
CA2230824C (en) | 2009-09-15 |
GB9519268D0 (en) | 1995-11-22 |
EP0853624B1 (en) | 2001-02-14 |
AU710980B2 (en) | 1999-10-07 |
EP0853624A1 (en) | 1998-07-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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