GR3034035T3 - A process for the preparation of factor ix from biological sources - Google Patents

A process for the preparation of factor ix from biological sources

Info

Publication number
GR3034035T3
GR3034035T3 GR20000401725T GR20000401725T GR3034035T3 GR 3034035 T3 GR3034035 T3 GR 3034035T3 GR 20000401725 T GR20000401725 T GR 20000401725T GR 20000401725 T GR20000401725 T GR 20000401725T GR 3034035 T3 GR3034035 T3 GR 3034035T3
Authority
GR
Greece
Prior art keywords
pct
factor
preparation
biological sources
sec
Prior art date
Application number
GR20000401725T
Other languages
English (en)
Inventor
Djuro Josic
Lutz Hoffer
Frank Morfeld
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of GR3034035T3 publication Critical patent/GR3034035T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
GR20000401725T 1995-02-25 2000-07-27 A process for the preparation of factor ix from biological sources GR3034035T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19506633A DE19506633A1 (de) 1995-02-25 1995-02-25 Verfahren zur Herstellung von Faktor IX aus biologischen Quellen
PCT/EP1996/000636 WO1996027003A1 (en) 1995-02-25 1996-02-14 A process for the preparation of factor ix from biological sources

Publications (1)

Publication Number Publication Date
GR3034035T3 true GR3034035T3 (en) 2000-11-30

Family

ID=7755037

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000401725T GR3034035T3 (en) 1995-02-25 2000-07-27 A process for the preparation of factor ix from biological sources

Country Status (20)

Country Link
US (1) US5919909A (el)
EP (1) EP0811058B1 (el)
JP (1) JPH11500910A (el)
KR (1) KR100436857B1 (el)
CN (1) CN1105779C (el)
AT (1) ATE194167T1 (el)
AU (1) AU697217B2 (el)
CA (1) CA2213577C (el)
DE (2) DE19506633A1 (el)
DK (1) DK0811058T3 (el)
EA (1) EA000222B1 (el)
ES (1) ES2147365T3 (el)
FI (1) FI119377B (el)
GR (1) GR3034035T3 (el)
IL (1) IL117157A (el)
MY (1) MY119366A (el)
PT (1) PT811058E (el)
UA (1) UA46005C2 (el)
WO (1) WO1996027003A1 (el)
ZA (1) ZA961450B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19506633A1 (de) * 1995-02-25 1996-08-29 Octapharma Ag Verfahren zur Herstellung von Faktor IX aus biologischen Quellen
AT405608B (de) * 1997-04-08 1999-10-25 Immuno Ag Verfahren zur inaktivierung von pathogenen, insbesondere von viren, in einem biologischen material
JP4855074B2 (ja) * 2003-09-30 2012-01-18 一般財団法人化学及血清療法研究所 高純度血液凝固ｉｘ因子調製物およびその精製方法
KR100567448B1 (ko) * 2003-11-05 2006-04-04 주식회사 인투젠 형질전환 동물의 유즙 전처리방법 및 이를 통한 인체단백질의 정제방법
ES2357132T3 (es) 2004-03-19 2011-04-19 Baxter International Inc. Factor ixa para el tratamiento de trastornos hemorrágicos.
US10928366B2 (en) * 2007-01-26 2021-02-23 Sigma-Aldrich Co. Llc Compositions and methods for combining protein precipitation and solid phase extraction
US10434492B2 (en) * 2007-01-26 2019-10-08 Sigma-Aldrich Co. Llc Compositions and methods for solid phase extraction of lipids
BR112012024550B1 (pt) * 2010-03-30 2020-12-08 Octapharma Ag processo de produção de uma proteína dependente de vitamina k livre de príons em uma sequência de purificação que emprega cromatografia
CN104560925B (zh) * 2014-12-30 2017-11-03 山东泰邦生物制品有限公司 一种从人凝血因子ⅸ层析废液中激活制备人凝血酶的方法
CN107540743A (zh) * 2017-10-11 2018-01-05 南岳生物制药有限公司 一种双层析法制备人纤维蛋白原的方法
CN111378029B (zh) * 2018-12-29 2023-05-05 四川远大蜀阳药业有限责任公司 一种人凝血因子ix的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3473407D1 (en) * 1983-05-02 1988-09-22 Immuno Ag Method of inactivating pathogens
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
DE3877529T2 (de) * 1987-10-23 1996-11-07 Centre Regional De Transfusion Herstellung von hoch-gereingtem menschlichen Faktor IX sowie anderem Plasmaproteinkonzentrat und dessen therapeutische Verwendung.
AT402261B (de) * 1991-01-25 1997-03-25 Immuno Ag Komplex enthaltend den gerinnungsfaktor ix
SG48282A1 (en) * 1991-03-01 1998-04-17 Centeon Llc Preparation of factor ix
ATE168274T1 (de) 1993-02-09 1998-08-15 Octapharma Ag Verfahren zur inaktivierung von viren, die nicht mit lipidhüllen versehen sind
DE19506633A1 (de) * 1995-02-25 1996-08-29 Octapharma Ag Verfahren zur Herstellung von Faktor IX aus biologischen Quellen

Also Published As

Publication number Publication date
DK0811058T3 (da) 2000-10-16
EA199700196A1 (ru) 1998-02-26
IL117157A0 (en) 1996-06-18
DE19506633A1 (de) 1996-08-29
DE69609054D1 (de) 2000-08-03
FI973469A0 (fi) 1997-08-22
AU697217B2 (en) 1998-10-01
JPH11500910A (ja) 1999-01-26
DE69609054T2 (de) 2001-03-08
ES2147365T3 (es) 2000-09-01
EP0811058B1 (en) 2000-06-28
CA2213577C (en) 2005-01-04
KR19980702453A (ko) 1998-07-15
EP0811058A1 (en) 1997-12-10
CA2213577A1 (en) 1996-09-06
ZA961450B (en) 1996-08-27
PT811058E (pt) 2000-10-31
CN1181782A (zh) 1998-05-13
UA46005C2 (uk) 2002-05-15
IL117157A (en) 1999-12-22
KR100436857B1 (ko) 2004-09-21
AU4876196A (en) 1996-09-18
FI119377B (fi) 2008-10-31
US5919909A (en) 1999-07-06
EA000222B1 (ru) 1998-12-24
CN1105779C (zh) 2003-04-16
FI973469A (fi) 1997-08-22
MY119366A (en) 2005-05-31
WO1996027003A1 (en) 1996-09-06
ATE194167T1 (de) 2000-07-15

Similar Documents

Publication Publication Date Title
IL138801A0 (en) Humanized antibody against human tissue factor and process for the preparation thereof
FR2824568B1 (fr) Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
DK0766745T3 (da) Monoklonalt antistof, som er specifikt for humant 4-1BB samt cellelinje, som producerer dette
DE69424545D1 (de) Verfahren zur herstellung von immunoglobulin g konzentrat
WO1990014067A3 (en) Methods for treating anxiety with sigma receptor ligands
IL117157A0 (en) Preparation of factor ix from biological sources
IN181859B (el)
SE9502921D0 (sv) New compounds
KR950700988A (ko) 미생물, 이들의 제조방법 및 이들의 사용(Micro-organisms, preparation method therefor and uses thereof)
TW326033B (en) Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same
ES2173879T3 (es) Procedimiento para la preparacion de conjugados a base de un participe especifico en la fijacion y de una proteina que contiene hidratos de carbono
ATE43610T1 (de) Acino-foetale differenzierungsproteine verbunden mit krebs des pankreas, antiserum und monoklonale antikoerper gegen diese proteine und verfahren zu ihrer herstellung.
ATE309371T1 (de) Protein mit dnase-aktivität
DE69802171T8 (de) Verfahren zur Herstellung von 5,6-Dihydro-11H-dibenzo[a,d]cyclohept-11-enen
ZA961044B (en) New pyridine and pyridazine derivatives, processes for the production thereof and pharmaceutical agents containing these compounds.
DE59603908D1 (de) Verfahren zur Herstellung von N',N'-disubstituierten 1,4-Diaminoanthrachinonen
UA42749C2 (uk) N,n-діетил-8,8-дипропіл-2-азаспіро[4,5]декан-2-пропанамін дималеат, фармацевтична композиція, спосіб лікування
DE59611353D1 (de) Transketolase-verwandtes protein
ATE105570T1 (de) Modifizierte menschliche anti-rh(d)-antikoerper.
DE59610341D1 (de) Verfahren zur Herstellung von 2,4,6-Trichlorpyrimidin
HU9603631D0 (en) Pharmaceutical compositions
MX9605668A (es) Sal de estilbazolio, su preparacion y uso.
NZ505580A (en) Method of treating immunodeficiences using neutrokine alpha
UA29106A (uk) Спосіб лікування вібраційної хвороби

Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees