GR3033583T3 - Anticoagulant peptide aldehyde derivatives - Google Patents
Anticoagulant peptide aldehyde derivativesInfo
- Publication number
- GR3033583T3 GR3033583T3 GR20000401278T GR20000401278T GR3033583T3 GR 3033583 T3 GR3033583 T3 GR 3033583T3 GR 20000401278 T GR20000401278 T GR 20000401278T GR 20000401278 T GR20000401278 T GR 20000401278T GR 3033583 T3 GR3033583 T3 GR 3033583T3
- Authority
- GR
- Greece
- Prior art keywords
- pct
- aldehyde derivatives
- peptide aldehyde
- sec
- formula
- Prior art date
Links
- 239000003146 anticoagulant agent Substances 0.000 title abstract 3
- 229940127219 anticoagulant drug Drugs 0.000 title abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- -1 2-cycloheptyl-2-hydroxyacetyl Chemical group 0.000 abstract 2
- 125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 abstract 2
- 125000002059 L-arginyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 abstract 1
- 230000000702 anti-platelet effect Effects 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9601527A HU222199B1 (hu) | 1996-06-05 | 1996-06-05 | Véralvadásgátló hatású peptid-aldehid-származékok és a vegyületeket tartalmazó gyógyszerkészítmények |
| PCT/HU1997/000027 WO1997046523A1 (en) | 1996-06-05 | 1997-06-05 | Anticoagulant peptide aldehyde derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3033583T3 true GR3033583T3 (en) | 2000-09-29 |
Family
ID=89994026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20000401278T GR3033583T3 (en) | 1996-06-05 | 2000-05-31 | Anticoagulant peptide aldehyde derivatives |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6121241A (el) |
| EP (1) | EP0863871B1 (el) |
| AT (1) | ATE190316T1 (el) |
| AU (1) | AU717777B2 (el) |
| DE (1) | DE69701381T2 (el) |
| ES (1) | ES2146096T3 (el) |
| GR (1) | GR3033583T3 (el) |
| HU (1) | HU222199B1 (el) |
| PT (1) | PT863871E (el) |
| WO (1) | WO1997046523A1 (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1425009A4 (en) * | 2001-08-21 | 2006-10-25 | Ivax Inst For Drug Res Ltd | PEPTIDE ARGINALS AND METHOD FOR THE TREATMENT OF DISSEMINATED INTRAVASCULAR COAGULATION |
| DE10239821A1 (de) | 2002-08-29 | 2004-03-11 | Roche Diagnostics Gmbh | Verbesserung der Spezifität bei der Bestimmung von Antithrombin |
| AU2003302238A1 (en) | 2002-12-03 | 2004-06-23 | Axys Pharmaceuticals, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors |
| WO2009068926A1 (en) | 2007-11-30 | 2009-06-04 | University Of Debrecen | Use of urokinase type plasminogen activator inhibitors for the treatment of corneal disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU192646B (en) * | 1984-12-21 | 1987-06-29 | Gyogyszerkutato Intezet | Process for preparing new n-alkyl-peptide aldehydes |
| IL99527A (en) * | 1990-09-28 | 1997-08-14 | Lilly Co Eli | Tripeptide antithrombotic agents |
| WO1993015756A1 (en) * | 1992-02-14 | 1993-08-19 | Corvas International, Inc. | Inhibitors of thrombosis |
| JPH08504769A (ja) * | 1992-12-15 | 1996-05-21 | コルバス・インターナショナル、インコーポレイテッド | 因子Ｘａの新規インヒビター |
-
1996
- 1996-06-05 HU HU9601527A patent/HU222199B1/hu not_active IP Right Cessation
-
1997
- 1997-06-05 US US09/011,001 patent/US6121241A/en not_active Expired - Fee Related
- 1997-06-05 AU AU30435/97A patent/AU717777B2/en not_active Ceased
- 1997-06-05 DE DE69701381T patent/DE69701381T2/de not_active Expired - Fee Related
- 1997-06-05 WO PCT/HU1997/000027 patent/WO1997046523A1/en active IP Right Grant
- 1997-06-05 EP EP97925209A patent/EP0863871B1/en not_active Expired - Lifetime
- 1997-06-05 ES ES97925209T patent/ES2146096T3/es not_active Expired - Lifetime
- 1997-06-05 AT AT97925209T patent/ATE190316T1/de not_active IP Right Cessation
- 1997-06-05 PT PT97925209T patent/PT863871E/pt unknown
-
2000
- 2000-05-31 GR GR20000401278T patent/GR3033583T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT863871E (pt) | 2000-08-31 |
| ATE190316T1 (de) | 2000-03-15 |
| HUP9601527A3 (en) | 1999-03-01 |
| EP0863871B1 (en) | 2000-03-08 |
| WO1997046523A1 (en) | 1997-12-11 |
| AU717777B2 (en) | 2000-03-30 |
| EP0863871A1 (en) | 1998-09-16 |
| DE69701381D1 (de) | 2000-04-13 |
| HU222199B1 (hu) | 2003-05-28 |
| HU9601527D0 (en) | 1996-08-28 |
| AU3043597A (en) | 1998-01-05 |
| HUP9601527A2 (hu) | 1998-10-28 |
| DE69701381T2 (de) | 2000-11-16 |
| US6121241A (en) | 2000-09-19 |
| ES2146096T3 (es) | 2000-07-16 |
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