GR3033487T3 - Thiazolidinedione derivatives, their production and use. - Google Patents
Thiazolidinedione derivatives, their production and use.Info
- Publication number
- GR3033487T3 GR3033487T3 GR20000401184T GR20000401184T GR3033487T3 GR 3033487 T3 GR3033487 T3 GR 3033487T3 GR 20000401184 T GR20000401184 T GR 20000401184T GR 20000401184 T GR20000401184 T GR 20000401184T GR 3033487 T3 GR3033487 T3 GR 3033487T3
- Authority
- GR
- Greece
- Prior art keywords
- residue
- nitrogen atom
- novel
- hypolipidemic
- atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34856892 | 1992-12-28 | ||
| JP18099693 | 1993-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3033487T3 true GR3033487T3 (en) | 2000-09-29 |
Family
ID=26500340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20000401184T GR3033487T3 (en) | 1992-12-28 | 2000-05-24 | Thiazolidinedione derivatives, their production and use. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5489602A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0605228B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP3741452B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100292363B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1056372C (cg-RX-API-DMAC7.html) |
| AT (1) | ATE190052T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU666414B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2112283A1 (cg-RX-API-DMAC7.html) |
| CZ (1) | CZ288363B6 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69327944T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0605228T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2142852T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI935887L (cg-RX-API-DMAC7.html) |
| GR (1) | GR3033487T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUT69383A (cg-RX-API-DMAC7.html) |
| MX (1) | MX9400190A (cg-RX-API-DMAC7.html) |
| MY (1) | MY110142A (cg-RX-API-DMAC7.html) |
| NO (1) | NO300735B1 (cg-RX-API-DMAC7.html) |
| PT (1) | PT605228E (cg-RX-API-DMAC7.html) |
| RU (1) | RU2129553C1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW245716B (cg-RX-API-DMAC7.html) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL113112A (en) * | 1994-03-28 | 2000-06-01 | Nissan Chemical Ind Ltd | Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them |
| EP0783496B9 (en) * | 1994-08-10 | 2003-09-03 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, their production and use |
| US5641796A (en) * | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
| US5925656A (en) * | 1995-04-10 | 1999-07-20 | Dr. Reddy's Research Foundation | Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| ZA973850B (en) * | 1996-05-06 | 1997-12-02 | Reddy Research Foundation | Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them. |
| US5919782A (en) * | 1996-05-06 | 1999-07-06 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US5889032A (en) * | 1996-05-06 | 1999-03-30 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US5801173A (en) * | 1996-05-06 | 1998-09-01 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US6372750B2 (en) | 1996-07-01 | 2002-04-16 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases |
| USRE39266E1 (en) | 1996-07-01 | 2006-09-05 | Dr. Reddy's Laboratories, Limited | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| US5885997A (en) * | 1996-07-01 | 1999-03-23 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| US6114526A (en) * | 1996-07-01 | 2000-09-05 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| KR100579765B1 (ko) | 1996-07-01 | 2006-12-28 | 닥터 레디스 레보러터리즈 리미티드 | 신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도 |
| CN1221417A (zh) * | 1996-07-26 | 1999-06-30 | 雷迪博士研究基金会 | 具有抗糖尿病、降低血脂、抗高血压性能的噻唑烷二酮化合物,其制备方法及其药物组合物 |
| DE69723869T2 (de) * | 1996-12-31 | 2004-04-22 | Dr. Reddy's Laboratories Ltd. | Heterozyklische verbindungen, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen die diese enthalten und ihre anwendung in der behandlung von diabetis und verwandten krankheiten |
| TW577875B (en) * | 1997-01-31 | 2004-03-01 | Shionogi & Co | Pyrrolidine derivatives with inhibitory activity for phospholipase A2 |
| JP2001518069A (ja) * | 1997-05-02 | 2001-10-09 | ドクター・レディーズ・リサーチ・ファウンデーション | 低脂質性、抗高血圧性特性を有する新規な抗糖尿病化合物、それらの製造方法及びそれらを含有する薬学的組成物 |
| GB9726568D0 (en) * | 1997-12-16 | 1998-02-11 | Smithkline Beecham Plc | Novel pharmaceutical |
| IL143299A0 (en) * | 1998-12-01 | 2002-04-21 | Novo Nordisk As | Pharmaceutical composition comprising 5-[[4- [3-methyl-4-oxo-3, 4-dihydro-2-quinazolinyl] methoxy] phenyl-methyl] thiadiazolidine-2, 4-dione and the process for its preparation |
| JP4316787B2 (ja) * | 2000-01-11 | 2009-08-19 | 壽製薬株式会社 | エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、 |
| US20030212138A1 (en) * | 2002-01-14 | 2003-11-13 | Pharmacia Corporation | Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor |
| US20030220374A1 (en) * | 2002-01-14 | 2003-11-27 | Pharmacia Corporation | Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors |
| WO2004100895A2 (en) * | 2003-05-13 | 2004-11-25 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders |
| US7833513B2 (en) | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
| WO2011079274A1 (en) * | 2009-12-23 | 2011-06-30 | Jasco Pharmaceuticals, LLC | Aminopyrimidine kinase inhibitors |
| CN101824032B (zh) * | 2010-04-23 | 2015-09-09 | 浙江华海药业股份有限公司 | 一种制备盐酸吡格列酮的工艺改进方法 |
| BR112014010563B1 (pt) | 2011-11-04 | 2021-01-12 | Jasco Pharmaceuticals, LLC | compostos inibidores da aminopirimidina quinase |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5364586A (en) * | 1976-11-19 | 1978-06-09 | Takeda Chemical Industries Ltd | Emission driving device for blood detector |
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| JPS5564586A (en) * | 1978-11-09 | 1980-05-15 | Takeda Chem Ind Ltd | Thiazolidine derivative |
| US4296237A (en) * | 1979-09-11 | 1981-10-20 | Merck & Co., Inc. | 4-(Pyridyl, piperazinyl and thiazolyl substituted thiazolyl)-3-hydroxy-3-pyrroline-2,5-diones |
| CA1206151A (en) * | 1981-12-28 | 1986-06-17 | Richard P. Pioch | Pyrimidone anti-ulcer agents |
| CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物，其制备方法和用途 |
| WO1986006069A1 (fr) * | 1985-04-09 | 1986-10-23 | Takeda Chemical Industries, Ltd. | Derives de thiazolidinedione, leur procede de preparation et composition medicinale les contenant |
| JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
| US5130379A (en) * | 1988-03-08 | 1992-07-14 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| MX15171A (es) * | 1988-03-08 | 1993-05-01 | Pfizer | Derivados de tiazolidinodiona hipoglicemicos |
| US5143930A (en) * | 1990-02-07 | 1992-09-01 | Sankyo Company, Limited | Thiazolidine derivatives with anti-diabetic activity, their preparation and their use |
| RU2066322C1 (ru) * | 1991-06-28 | 1996-09-10 | Киевский Государственный Университет Им.Т.Г.Шевченко | 3-(4-метил-2-тиазолил)-6-пропил-7-(1-метил-1-этоксикарбонил)метоксихромон, обладающий гипогликемическим, гиполипидемическим действием и аналептическим действием |
-
1993
- 1993-12-15 TW TW082110623A patent/TW245716B/zh active
- 1993-12-20 MY MYPI93002764A patent/MY110142A/en unknown
- 1993-12-21 AU AU52613/93A patent/AU666414B2/en not_active Ceased
- 1993-12-23 CA CA002112283A patent/CA2112283A1/en not_active Abandoned
- 1993-12-23 DK DK93310529T patent/DK0605228T3/da active
- 1993-12-23 DE DE69327944T patent/DE69327944T2/de not_active Expired - Fee Related
- 1993-12-23 ES ES93310529T patent/ES2142852T3/es not_active Expired - Lifetime
- 1993-12-23 AT AT93310529T patent/ATE190052T1/de not_active IP Right Cessation
- 1993-12-23 PT PT93310529T patent/PT605228E/pt unknown
- 1993-12-23 EP EP93310529A patent/EP0605228B1/en not_active Expired - Lifetime
- 1993-12-23 CZ CZ19932876A patent/CZ288363B6/cs not_active IP Right Cessation
- 1993-12-24 JP JP32839193A patent/JP3741452B2/ja not_active Expired - Fee Related
- 1993-12-27 KR KR1019930029987A patent/KR100292363B1/ko not_active Expired - Fee Related
- 1993-12-27 HU HU9303757A patent/HUT69383A/hu unknown
- 1993-12-27 FI FI935887A patent/FI935887L/fi unknown
- 1993-12-27 NO NO934833A patent/NO300735B1/no not_active IP Right Cessation
- 1993-12-27 RU RU93056838A patent/RU2129553C1/ru active
- 1993-12-28 CN CN93121754A patent/CN1056372C/zh not_active Expired - Fee Related
-
1994
- 1994-01-03 MX MX9400190A patent/MX9400190A/es not_active IP Right Cessation
-
1995
- 1995-01-23 US US08/376,529 patent/US5489602A/en not_active Expired - Lifetime
-
2000
- 2000-05-24 GR GR20000401184T patent/GR3033487T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI935887A7 (fi) | 1994-06-29 |
| HUT69383A (en) | 1995-09-28 |
| FI935887A0 (fi) | 1993-12-27 |
| JP3741452B2 (ja) | 2006-02-01 |
| US5489602A (en) | 1996-02-06 |
| NO300735B1 (no) | 1997-07-14 |
| CA2112283A1 (en) | 1994-06-29 |
| HU9303757D0 (en) | 1994-04-28 |
| CN1056372C (zh) | 2000-09-13 |
| ATE190052T1 (de) | 2000-03-15 |
| DE69327944T2 (de) | 2000-10-19 |
| AU666414B2 (en) | 1996-02-08 |
| PT605228E (pt) | 2000-06-30 |
| CZ288363B6 (en) | 2001-06-13 |
| NO934833D0 (no) | 1993-12-27 |
| KR940014392A (ko) | 1994-07-18 |
| NO934833L (no) | 1994-06-29 |
| JPH0782269A (ja) | 1995-03-28 |
| CN1094726A (zh) | 1994-11-09 |
| KR100292363B1 (ko) | 2001-09-17 |
| CZ287693A3 (en) | 1994-12-15 |
| EP0605228B1 (en) | 2000-03-01 |
| TW245716B (cg-RX-API-DMAC7.html) | 1995-04-21 |
| MY110142A (en) | 1998-02-28 |
| AU5261393A (en) | 1994-07-07 |
| DE69327944D1 (de) | 2000-04-06 |
| MX9400190A (es) | 1994-07-29 |
| DK0605228T3 (da) | 2000-06-05 |
| EP0605228A1 (en) | 1994-07-06 |
| ES2142852T3 (es) | 2000-05-01 |
| FI935887L (fi) | 1994-06-29 |
| RU2129553C1 (ru) | 1999-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ML | Lapse due to non-payment of fees |