GR3019789T3 - Stimulation of hair growth with potassium channel openers and 5-alpha-reductase inhibitors - Google Patents

Stimulation of hair growth with potassium channel openers and 5-alpha-reductase inhibitors

Info

Publication number
GR3019789T3
GR3019789T3 GR960401169T GR960401169T GR3019789T3 GR 3019789 T3 GR3019789 T3 GR 3019789T3 GR 960401169 T GR960401169 T GR 960401169T GR 960401169 T GR960401169 T GR 960401169T GR 3019789 T3 GR3019789 T3 GR 3019789T3
Authority
GR
Greece
Prior art keywords
alpha
potassium channel
hair growth
reductase inhibitors
stimulation
Prior art date
Application number
GR960401169T
Other languages
English (en)
Inventor
Arthur Robert Diani
Allen Edwin Buhl
Heinrich Josef Schostarez
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GR3019789T3 publication Critical patent/GR3019789T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR960401169T 1990-08-10 1996-04-29 Stimulation of hair growth with potassium channel openers and 5-alpha-reductase inhibitors GR3019789T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56577790A 1990-08-10 1990-08-10
PCT/US1991/005170 WO1992002225A1 (en) 1990-08-10 1991-07-29 STIMULATION OF HAIR GROWTH WITH POTASSIUM CHANNEL OPENERS AND 5α-REDUCTASE INHIBITORS

Publications (1)

Publication Number Publication Date
GR3019789T3 true GR3019789T3 (en) 1996-07-31

Family

ID=24260045

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401169T GR3019789T3 (en) 1990-08-10 1996-04-29 Stimulation of hair growth with potassium channel openers and 5-alpha-reductase inhibitors

Country Status (12)

Country Link
US (1) US5578599A (el)
EP (1) EP0542802B1 (el)
JP (1) JP3004718B2 (el)
KR (1) KR100192734B1 (el)
AT (1) ATE134877T1 (el)
AU (1) AU646069B2 (el)
CA (1) CA2085605C (el)
DE (1) DE69117762T2 (el)
DK (1) DK0542802T3 (el)
ES (1) ES2084175T3 (el)
GR (1) GR3019789T3 (el)
WO (1) WO1992002225A1 (el)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516768A (en) * 1990-03-16 1996-05-14 Smithkline Beecham Corporation Uncompetitive inhibition of steroid and 5α-reductose
GB2274060A (en) * 1993-01-07 1994-07-13 Merck & Co Inc Treatment of patterned alopecia with 17ß-acyl-4-aza-5-androst-1-ene-3-ones and minoxidil
AU6083494A (en) * 1993-01-07 1994-08-15 Merck & Co., Inc. Combination method for treating patterned alopecia with 17beta -n-substituted-carbamoyl-4-aza-5alpha-androst-1-en-3- ones and minoxidil
US5407944A (en) * 1993-02-19 1995-04-18 Goldman; Boris E. Compositions and methods for promoting hair growth
WO1995000147A1 (en) * 1993-06-28 1995-01-05 Merck & Co., Inc. 4-AZA-PREGNANE 5α-REDUCTASE ISOZYME 1 INHIBITORS
TW382595B (en) * 1993-10-15 2000-02-21 Merck & Co Inc Pharmaceutical composition for use in arresting and reversing androgenic alopecia
US5547957A (en) * 1993-10-15 1996-08-20 Merck & Co., Inc. Method of treating androgenic alopecia with 5-α reductase inhibitors
AU1097995A (en) * 1993-11-18 1995-06-06 Merck & Co., Inc. Combination method for the treatment of patterned alopecia
FR2717381B1 (fr) * 1994-03-15 1996-04-19 Oreal Compositions à base d'alpha-pyrones pour induire et stimuler la croissance des cheveux et/ou freiner leur chute et utilisation.
US5886005A (en) * 1995-01-17 1999-03-23 Merck & Co., Inc. 4-Aza-19-norandrostane derivatives
WO1997014418A1 (en) * 1995-10-19 1997-04-24 Merck & Co., Inc. 16-substituted-6-aza-steroid 5-alpha-reductase inhibitors
JPH10203933A (ja) * 1997-01-27 1998-08-04 Kao Corp 養毛・育毛料
US6013668A (en) * 1997-08-13 2000-01-11 Bristol-Myers Squibb Company Enantiomers of 4-[[(cyanoimino) [(1,2,2-trimethylpropyl) amino]methyl]amino]benzonitrile
US6458835B2 (en) 1997-08-13 2002-10-01 Bristol-Myers Squibb Company Method of inhibiting or treating chemotherapy-induced hair loss
AUPO983897A0 (en) * 1997-10-17 1997-11-06 Soltec Research Pty Ltd Topical antifungal composition
AUPP310798A0 (en) * 1998-04-22 1998-05-14 Soltec Research Pty Ltd Vehicle system for a composition comprising a piperidinopyrimidine derivative
GB9909792D0 (en) * 1998-12-04 1999-06-23 Cambridge Bioclinical Limited Potassium channel activators and their use
US7018979B1 (en) 2000-01-26 2006-03-28 Cedars-Sinai Medical Center Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor
US20050153940A1 (en) * 2000-01-26 2005-07-14 Cedars-Sinai Medical Center Method for using potassium channel activation for delivering a medicant to an abnormal brain region and/or a malignant tumor
US6596266B2 (en) 2000-02-18 2003-07-22 Natural Science, Inc. Compositions containing minoxidil and saw palmetto for treating baldness
KR20020005332A (ko) * 2000-07-10 2002-01-17 정상훈 탈모증 치료용 키트
DE10036799A1 (de) * 2000-07-28 2002-02-07 Beiersdorf Ag Neues Mittel zur Behandlung der Haare und der Kopfhaut
SE0100374D0 (sv) * 2001-02-07 2001-02-07 Pharmacia Ab Novel compositions of potassium channel openers and protein kinase c inhibitors and use thereof
US7211561B2 (en) * 2001-10-12 2007-05-01 Cedars-Sinai Medical Center Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa)
SE0104421D0 (sv) * 2001-12-21 2001-12-21 Ponsus Pharma Ab New composition
EP1850852A4 (en) * 2005-02-22 2009-11-18 Cedars Sinai Medical Center USE OF SILDENAFIL, VARDENAFIL AND OTHER 5-PHOSPHODIESTERASE INHIBITORS TO INCREASE THE PERMEABILITY OF THE ABNORMAL BLOOD-BRAIN DISEASE
US7914548B2 (en) * 2006-04-17 2011-03-29 Ustuner E Tuncay Prevention or treatment of male pattern baldness method and device
EP2343061A1 (en) 2009-12-28 2011-07-13 Lipofoods, S.L. Use of tall oil pitch extract and compositions which contain it
KR101205209B1 (ko) * 2011-04-25 2012-11-27 박준형 탈모방지 및 발모촉진용 외용제 조성물
WO2015157771A1 (en) * 2014-04-11 2015-10-15 Bcs Business Consulting Services Pte Ltd Hair enhancing formulation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596812A (en) * 1976-05-24 1986-06-24 The Upjohn Company Methods and solutions for treating male pattern alopecia
US4139619A (en) * 1976-05-24 1979-02-13 The Upjohn Company 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth
AU584070B2 (en) * 1983-12-12 1989-05-18 Edwin G. Kaszynski Hair growth modification
US4684635A (en) * 1984-05-11 1987-08-04 Norman Orentreich Compositions and methods for inhibiting the action of androgens
DE3688427T2 (de) * 1985-07-18 1993-08-26 Peter H Proctor Topische zusammensetzung und verfahren zur anregung des haarwuchses.
DE3615396A1 (de) * 1986-05-07 1987-11-12 Wella Ag Mittel zur behandlung der haare und der kopfhaut
JPH02502818A (ja) * 1987-03-30 1990-09-06 ジ・アップジョン・カンパニー 遺伝性脱毛症を治療するためのミノキシジルおよび抗炎症剤の組合わせ
US5026691A (en) * 1987-03-30 1991-06-25 The Upjohn Company Combination of minoxidil and an antiinflammatory agent for treating patterned alopecia
EP0285382B1 (en) * 1987-04-03 1994-04-13 Merck & Co. Inc. Treatment of androgenic alopecia with 17beta-n-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones
JPH01305017A (ja) * 1988-05-31 1989-12-08 Yakurigaku Chuo Kenkyusho:Kk 脱毛症治療剤
KR910700039A (ko) * 1988-12-02 1991-03-13 로버트 에이. 아미테이지 탈모증 치료용의 미녹시딜 및 혈관수축제 조성물

Also Published As

Publication number Publication date
DE69117762D1 (de) 1996-04-11
WO1992002225A1 (en) 1992-02-20
CA2085605A1 (en) 1992-02-11
AU646069B2 (en) 1994-02-03
CA2085605C (en) 2003-03-11
KR100192734B1 (ko) 1999-06-15
JPH06500081A (ja) 1994-01-06
ATE134877T1 (de) 1996-03-15
EP0542802A1 (en) 1993-05-26
DE69117762T2 (de) 1996-08-08
DK0542802T3 (da) 1996-07-22
ES2084175T3 (es) 1996-05-01
US5578599A (en) 1996-11-26
JP3004718B2 (ja) 2000-01-31
EP0542802B1 (en) 1996-03-06
AU8301091A (en) 1992-03-02

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