GR3002299T3 - Composition of pregnanolole comprising a stable oil-in-water emulsion - Google Patents

Composition of pregnanolole comprising a stable oil-in-water emulsion

Info

Publication number
GR3002299T3
GR3002299T3 GR91400996T GR910400996T GR3002299T3 GR 3002299 T3 GR3002299 T3 GR 3002299T3 GR 91400996 T GR91400996 T GR 91400996T GR 910400996 T GR910400996 T GR 910400996T GR 3002299 T3 GR3002299 T3 GR 3002299T3
Authority
GR
Greece
Prior art keywords
composition
water emulsion
pregnanolole
stable oil
pregnanolone
Prior art date
Application number
GR91400996T
Other languages
Greek (el)
English (en)
Inventor
Roland Ingolf Jeppsson
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of GR3002299T3 publication Critical patent/GR3002299T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
GR91400996T 1986-02-13 1991-07-11 Composition of pregnanolole comprising a stable oil-in-water emulsion GR3002299T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8600632A SE8600632D0 (sv) 1986-02-13 1986-02-13 Novel pharmaceutical composition

Publications (1)

Publication Number Publication Date
GR3002299T3 true GR3002299T3 (en) 1992-12-30

Family

ID=20363448

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91400996T GR3002299T3 (en) 1986-02-13 1991-07-11 Composition of pregnanolole comprising a stable oil-in-water emulsion

Country Status (14)

Country Link
US (1) US5028600A (enExample)
EP (1) EP0233849B1 (enExample)
JP (1) JPH0788305B2 (enExample)
AT (1) ATE64526T1 (enExample)
CA (1) CA1301651C (enExample)
DE (1) DE3770830D1 (enExample)
DK (1) DK175504B1 (enExample)
ES (1) ES2037742T3 (enExample)
FI (1) FI88676C (enExample)
GR (1) GR3002299T3 (enExample)
HK (1) HK83293A (enExample)
NO (1) NO175040B (enExample)
SE (1) SE8600632D0 (enExample)
SG (1) SG102892G (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302295D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab New pharmaceutical composition
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
WO1999007381A1 (en) * 1997-08-11 1999-02-18 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
JP4198318B2 (ja) 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
EP1539104A2 (en) * 2000-12-29 2005-06-15 The Trustees Of Columbia University In The City Of New York Use of iv emulsions with different triglyceride composition, particle size and apolipoprotein e for targeted tissue delivery of hydrophobic compounds
MXPA04012756A (es) * 2002-07-02 2005-03-23 Altana Pharma Ag Suspension acuosa esteril que contiene ciclesonida.
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
WO2006030450A2 (en) * 2004-09-13 2006-03-23 Bharat Serums & Vaccines Ltd. Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy
WO2012096697A1 (en) * 2011-01-14 2012-07-19 Simpkins Cuthbert O Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
US10478505B2 (en) 2011-09-23 2019-11-19 The Regents Of The University Of California Edible oils to enhance delivery of orally administered steroids
SMT202000008T1 (it) 2012-01-23 2020-03-13 Sage Therapeutics Inc Formulazione di steroide neuroattivo comprendente un complesso di allopregnanolone e solfobutil eter beta-ciclodestrina
WO2014028398A2 (en) 2012-08-13 2014-02-20 The Regents Of The University Of California Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
PL2887944T3 (pl) 2012-08-21 2022-02-21 Sage Therapeutics, Inc. Allopregnanolon do leczenia lekoopornego stanu padaczkowego
ES2973320T3 (es) 2012-11-30 2024-06-19 Univ California Alopregnanolona para tratar, reducir o mitigar los síntomas de la depresión posparto
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
RU2766155C2 (ru) 2016-03-08 2022-02-08 Сейдж Терапьютикс, Инк. Нейроактивные стероиды, их композиции и применения
AU2019396217A1 (en) * 2018-12-10 2021-07-08 Halo Science LLC Stable formulations of anesthetics and associated dosage forms
CA3151334C (en) * 2019-08-19 2024-04-09 Arizona Board Of Regents On Behalf Of The University Of Arizona Topical neurosteroid formulations
US11969434B1 (en) 2022-08-29 2024-04-30 Lipocine Inc. Oral allopregnanolone compositions and methods of use
CN114344309B (zh) * 2021-12-30 2024-02-06 南京迈诺威医药科技有限公司 一种别孕烷醇酮衍生物自乳化制剂及其制备方法
US12186327B2 (en) 2022-08-29 2025-01-07 Lipocine Inc. Oral allopregnanolone compositions and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1215702B (de) * 1962-07-03 1966-05-05 Merck Ag E Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen
CA895860A (en) * 1969-11-05 1972-03-21 Kruger Gunther PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) * 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液

Also Published As

Publication number Publication date
DK175504B1 (da) 2004-11-15
JPH0788305B2 (ja) 1995-09-27
SG102892G (en) 1992-12-04
FI870589L (fi) 1987-08-14
EP0233849A1 (en) 1987-08-26
FI870589A0 (fi) 1987-02-12
SE8600632D0 (sv) 1986-02-13
NO870560D0 (no) 1987-02-12
ATE64526T1 (de) 1991-07-15
US5028600A (en) 1991-07-02
FI88676C (fi) 1993-06-28
EP0233849B1 (en) 1991-06-19
NO175040C (enExample) 1994-08-24
ES2037742T3 (es) 1993-07-01
DK62187D0 (da) 1987-02-06
DK62187A (da) 1987-08-14
CA1301651C (en) 1992-05-26
FI88676B (fi) 1993-03-15
NO175040B (no) 1994-05-16
DE3770830D1 (de) 1991-07-25
NO870560L (no) 1987-08-14
JPS62192322A (ja) 1987-08-22
HK83293A (en) 1993-08-20

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