GEP20043257B - Aerosol Particles Resistant to Hygrosscopic Growth, Method for Their Production and Use Thereof for Delivering an Active Agent to the Lung of A Human Patient by Inhalation - Google Patents
Aerosol Particles Resistant to Hygrosscopic Growth, Method for Their Production and Use Thereof for Delivering an Active Agent to the Lung of A Human Patient by InhalationInfo
- Publication number
- GEP20043257B GEP20043257B GEAP19995857A GEAP1999005857A GEP20043257B GE P20043257 B GEP20043257 B GE P20043257B GE AP19995857 A GEAP19995857 A GE AP19995857A GE AP1999005857 A GEAP1999005857 A GE AP1999005857A GE P20043257 B GEP20043257 B GE P20043257B
- Authority
- GE
- Georgia
- Prior art keywords
- active agent
- lung
- delivering
- human patient
- growth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10016398P | 1998-09-14 | 1998-09-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20043257B true GEP20043257B (en) | 2004-06-25 |
Family
ID=22278404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GEAP19995857A GEP20043257B (en) | 1998-09-14 | 1999-09-13 | Aerosol Particles Resistant to Hygrosscopic Growth, Method for Their Production and Use Thereof for Delivering an Active Agent to the Lung of A Human Patient by Inhalation |
Country Status (44)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000075281A2 (en) | 1999-06-09 | 2000-12-14 | University Technology Corporation | Supercritical fluid-assisted nebulization and bubble drying |
| US6475468B2 (en) * | 2001-02-15 | 2002-11-05 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| CA2446904A1 (en) * | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| EG24184A (en) * | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| JP2005518453A (ja) | 2002-02-25 | 2005-06-23 | ディフュージョン・ファーマシューティカルズ・エルエルシー | 二極性トランスカロテノイド塩およびそれらの使用 |
| EP1539246A4 (en) * | 2002-07-03 | 2007-05-16 | Brigham & Womens Hospital | ADMINISTRATION IN THE CENTRAL AIRWAYS FOR THE SYSTEMIC DELIVERY OF THERAPEUTICS |
| BR0317392A (pt) * | 2002-12-19 | 2005-12-20 | Pharmacia Corp | Formulação não-higroscópica incluindo uma droga higroscópica |
| DE10338403A1 (de) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum |
| GB0327723D0 (en) * | 2003-09-15 | 2003-12-31 | Vectura Ltd | Pharmaceutical compositions |
| US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| MXPA06012240A (es) * | 2004-04-23 | 2007-01-31 | Cydex Inc | Formulacion para inhalador de polvo seco que contiene eter sulfoalquilico-ciclodextrina. |
| NZ561664A (en) | 2005-02-24 | 2011-02-25 | Diffusion Pharmaceuticals Llc | Trans carotenoids, their synthesis, formulation and uses |
| EP1857114A1 (en) * | 2005-03-09 | 2007-11-21 | Ono Pharmaceutical Co., Ltd. | Particle and preparation containing the particle |
| US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
| PT2583668E (pt) | 2005-10-26 | 2015-01-05 | Cydex Pharmaceuticals Inc | Composições de éter sulfoalquílico de ciclodextrina e métodos para a sua preparação |
| US20080035143A1 (en) * | 2006-08-14 | 2008-02-14 | Sievers Robert E | Human-powered dry powder inhaler and dry powder inhaler compositions |
| CN101541311B (zh) * | 2006-10-25 | 2013-01-23 | 大日本住友制药株式会社 | 不易结块的颗粒制剂 |
| EP1925295A1 (de) * | 2006-11-22 | 2008-05-28 | Boehringer Ingelheim Pharma GmbH & Co. KG | Stabile Pulverformulierung enthaltend ein Anticholinergikum |
| CN101687757A (zh) | 2007-04-13 | 2010-03-31 | 扩散药品有限公司 | 双极性反式类胡萝卜素作为预治疗及其在周围血管疾病的治疗中的应用 |
| BRPI0818119A2 (pt) | 2007-10-31 | 2015-08-04 | Diffusion Pharmaceuticals Llc | Uma nova classe de produtos terapêuticos que melhoram difusão de molécula pequena |
| ES2661215T3 (es) | 2009-05-20 | 2018-03-28 | Aeras | Composiciones víricas; inmunógenas; secadas por pulverización; estables |
| EP3539542B1 (en) | 2009-06-22 | 2023-04-19 | Diffusion Pharmaceuticals LLC | Diffusion enhancing compounds and their use with a thrombolytic |
| AU2011262361A1 (en) | 2010-06-02 | 2013-01-10 | Diffusion Pharmaceuticals Llc | Oral formulations of bipolar trans carotenoids |
| BR112014026957A8 (pt) * | 2012-05-03 | 2018-01-16 | Janssen R&D Ireland | micropartícula, composição compreendendo a mesma, seu uso e sistema de distribuição nasal relacionados ao tratamento de infecções do trato respiratório superior |
| BR112015010601B1 (pt) * | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
| WO2015042352A1 (en) * | 2013-09-20 | 2015-03-26 | Virginia Commonwealth University | Delivery of particles using hygroscopic excipients |
| AU2015338717B2 (en) | 2014-10-31 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Powder formulation |
| JP7032320B2 (ja) | 2016-03-24 | 2022-03-08 | ディフュージョン・ファーマシューティカルズ・エルエルシー | 癌を処置するための、化学療法及び放射線療法を伴う二極性トランスカロテノイドの使用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3155573A (en) * | 1958-05-06 | 1964-11-03 | Benger Lab Ltd | Inhalant composition and method of making same |
| ATE222754T1 (de) * | 1992-06-12 | 2002-09-15 | Teijin Ltd | Ultrafeines pulver zur inhalation und dessen herstellung |
| US6524557B1 (en) * | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| ATE287257T1 (de) * | 1997-01-16 | 2005-02-15 | Massachusetts Inst Technology | Zubereitung von partikelhaltigen arzneimitteln zur inhalation |
| US6086376A (en) * | 1998-01-30 | 2000-07-11 | Rtp Pharma Inc. | Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant |
-
1999
- 1999-09-09 MA MA25762A patent/MA25590A1/fr unknown
- 1999-09-13 GE GEAP19995857A patent/GEP20043257B/en unknown
- 1999-09-13 HU HU0103837A patent/HUP0103837A3/hu unknown
- 1999-09-13 ZA ZA200101995A patent/ZA200101995B/en unknown
- 1999-09-13 MY MYPI99003947A patent/MY129282A/en unknown
- 1999-09-13 AR ARP990104587A patent/AR022090A1/es unknown
- 1999-09-13 ID IDW20010582A patent/ID28845A/id unknown
- 1999-09-13 UA UA2001031707A patent/UA76085C2/uk unknown
- 1999-09-13 TR TR2001/01182T patent/TR200101182T2/xx unknown
- 1999-09-13 EA EA200100300A patent/EA003476B1/ru active IP Right Revival
- 1999-09-13 EP EP99969035A patent/EP1117442A1/en not_active Withdrawn
- 1999-09-13 JP JP2000569846A patent/JP2002524535A/ja not_active Withdrawn
- 1999-09-13 HN HN1999000159A patent/HN1999000159A/es unknown
- 1999-09-13 EE EEP200100151A patent/EE200100151A/xx unknown
- 1999-09-13 CZ CZ2001829A patent/CZ2001829A3/cs unknown
- 1999-09-13 CA CA002343920A patent/CA2343920A1/en not_active Abandoned
- 1999-09-13 YU YU24201A patent/YU24201A/sh unknown
- 1999-09-13 IL IL14156299A patent/IL141562A0/xx not_active IP Right Cessation
- 1999-09-13 WO PCT/US1999/021109 patent/WO2000015262A1/en not_active Application Discontinuation
- 1999-09-13 AP APAP/P/2001/002093A patent/AP1374A/en active
- 1999-09-13 NZ NZ510168A patent/NZ510168A/en unknown
- 1999-09-13 PL PL99346768A patent/PL195574B1/pl not_active IP Right Cessation
- 1999-09-13 SK SK344-2001A patent/SK3442001A3/sk unknown
- 1999-09-13 PE PE1999000925A patent/PE20001061A1/es not_active Application Discontinuation
- 1999-09-13 AU AU60397/99A patent/AU753014B2/en not_active Ceased
- 1999-09-13 CN CN99810871A patent/CN1317977A/zh active Pending
- 1999-09-13 BR BR9913722-4A patent/BR9913722A/pt not_active IP Right Cessation
- 1999-09-13 DZ DZ990192A patent/DZ2892A1/xx active
- 1999-09-13 OA OA1200100063A patent/OA11781A/en unknown
- 1999-09-13 TW TW088115876A patent/TWI226248B/zh not_active IP Right Cessation
- 1999-09-13 KR KR1020017003208A patent/KR20010075063A/ko not_active Application Discontinuation
- 1999-09-14 PA PA19998481901A patent/PA8481901A1/es unknown
- 1999-09-14 TN TNTNSN99173A patent/TNSN99173A1/fr unknown
- 1999-09-14 GT GT199900156A patent/GT199900156A/es unknown
- 1999-09-14 UY UY25711A patent/UY25711A1/es not_active Application Discontinuation
- 1999-09-14 CO CO99058265A patent/CO5130023A1/es unknown
- 1999-10-31 SA SA99200718A patent/SA99200718B1/ar unknown
-
2001
- 2001-02-21 IL IL141562A patent/IL141562A/en unknown
- 2001-03-05 IS IS5878A patent/IS5878A/is unknown
- 2001-03-13 NO NO20011251A patent/NO20011251L/no not_active Application Discontinuation
- 2001-03-14 LV LV010041A patent/LV12658B/xx unknown
- 2001-03-14 LT LT2001021A patent/LT4897B/lt not_active IP Right Cessation
- 2001-03-14 HR HR20010189A patent/HRP20010189A2/hr not_active Application Discontinuation
- 2001-04-10 BG BG105430A patent/BG105430A/xx unknown
-
2002
- 2002-03-06 HK HK02101738.3A patent/HK1042231A1/zh unknown
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