GB989755A - 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds - Google Patents
1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compoundsInfo
- Publication number
- GB989755A GB989755A GB48575/62A GB4857562A GB989755A GB 989755 A GB989755 A GB 989755A GB 48575/62 A GB48575/62 A GB 48575/62A GB 4857562 A GB4857562 A GB 4857562A GB 989755 A GB989755 A GB 989755A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzyl
- alkyl
- alkanoyl
- aroylpropyl
- benzimidazolinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 2
- -1 methoxyphenyl Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 abstract 1
- YFEOSTXFQCDCAR-UHFFFAOYSA-N 3-(1,2,3,6-tetrahydropyridin-4-yl)-1h-benzimidazol-2-one Chemical class O=C1NC2=CC=CC=C2N1C1=CCNCC1 YFEOSTXFQCDCAR-UHFFFAOYSA-N 0.000 abstract 1
- FKCKAEJWXGMCFZ-UHFFFAOYSA-N 3-(1-benzyl-3,6-dihydro-2h-pyridin-4-yl)-1h-benzimidazol-2-one Chemical compound O=C1NC2=CC=CC=C2N1C(CC1)=CCN1CC1=CC=CC=C1 FKCKAEJWXGMCFZ-UHFFFAOYSA-N 0.000 abstract 1
- BYNBAMHAURJNTR-UHFFFAOYSA-N 3-piperidin-4-yl-1h-benzimidazol-2-one Chemical compound O=C1NC2=CC=CC=C2N1C1CCNCC1 BYNBAMHAURJNTR-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000000994 L-ascorbates Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 125000003785 benzimidazolyl group Chemical group N1=C(NC2=C1C=CC=C2)* 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- ROSZJQBQGFBFSW-UHFFFAOYSA-N ethyl 1-benzyl-4-oxopiperidine-3-carboxylate Chemical compound C1CC(=O)C(C(=O)OCC)CN1CC1=CC=CC=C1 ROSZJQBQGFBFSW-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 230000000640 hydroxylating effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16142461A | 1961-12-22 | 1961-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB989755A true GB989755A (en) | 1965-04-22 |
Family
ID=22581117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB48575/62A Expired GB989755A (en) | 1961-12-22 | 1962-12-24 | 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE626307A (enrdf_load_stackoverflow) |
| CH (1) | CH450436A (enrdf_load_stackoverflow) |
| DK (1) | DK129714B (enrdf_load_stackoverflow) |
| FR (2) | FR2245M (enrdf_load_stackoverflow) |
| GB (1) | GB989755A (enrdf_load_stackoverflow) |
| NL (2) | NL287221A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446141A (en) * | 1978-06-02 | 1984-05-01 | Nobuhiro Nakamizo | Hypotensive piperidine derivatives |
| CN113637001A (zh) * | 2021-08-09 | 2021-11-12 | 安康市农业科学研究院 | 一种氟哌利多中间体的合成方法 |
-
0
- BE BE626307D patent/BE626307A/xx unknown
- NL NL135941D patent/NL135941C/xx active
- NL NL287221D patent/NL287221A/xx unknown
-
1962
- 1962-12-19 CH CH1491862A patent/CH450436A/de unknown
- 1962-12-21 FR FR919548A patent/FR2245M/fr active Active
- 1962-12-21 DK DK557362A patent/DK129714B/da unknown
- 1962-12-21 FR FR919549A patent/FR2246M/fr active Active
- 1962-12-24 GB GB48575/62A patent/GB989755A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4446141A (en) * | 1978-06-02 | 1984-05-01 | Nobuhiro Nakamizo | Hypotensive piperidine derivatives |
| CN113637001A (zh) * | 2021-08-09 | 2021-11-12 | 安康市农业科学研究院 | 一种氟哌利多中间体的合成方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK129714C (enrdf_load_stackoverflow) | 1975-04-21 |
| FR2245M (fr) | 1963-12-30 |
| FR2246M (fr) | 1963-12-30 |
| NL135941C (enrdf_load_stackoverflow) | |
| BE626307A (enrdf_load_stackoverflow) | |
| DE1470120A1 (de) | 1969-04-10 |
| CH450436A (de) | 1968-01-31 |
| DE1470120B2 (de) | 1975-05-28 |
| NL287221A (enrdf_load_stackoverflow) | |
| DK129714B (da) | 1974-11-11 |
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