GB974710A - Amino-alkylidene-dibenzocycloheptene derivatives - Google Patents

Amino-alkylidene-dibenzocycloheptene derivatives

Info

Publication number
GB974710A
GB974710A GB8504/62A GB850462A GB974710A GB 974710 A GB974710 A GB 974710A GB 8504/62 A GB8504/62 A GB 8504/62A GB 850462 A GB850462 A GB 850462A GB 974710 A GB974710 A GB 974710A
Authority
GB
United Kingdom
Prior art keywords
compounds
formula
alkylidene
amino
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8504/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH305461A external-priority patent/CH385833A/en
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of GB974710A publication Critical patent/GB974710A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The invention comprises compounds of general formula <FORM:0974710/C1/1> wherein X1 and X2 either each represent a hydrogen atom or together represent an additional bond, and R1 represents an alkyl radical having at most 5 carbon atoms; and their acid addition salts; and their preparation by hydrolysing or hydrogenolysing a compound of formula <FORM:0974710/C1/2> wherein Ac represents an organic acid radical or a functional derivative thereof. Acid derivatives II (e.g. N-carbethoxy-methylamino compounds) are prepared from tertiary amines of formula <FORM:0974710/C1/3> wherein R2 is benzyl, alkenyl or alkyl (e.g. dimethylamino compounds) which may themselves be obtained by reaction of the cyclohepten-5-ones with a substituted propyl metal compound followed by dehydration. Pharmaceutical compositions comprise compounds I and salts of the invention with carriers.
GB8504/62A 1961-03-14 1962-03-06 Amino-alkylidene-dibenzocycloheptene derivatives Expired GB974710A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH305461A CH385833A (en) 1961-03-14 1961-03-14 Process for the production of new amines
CH385161 1961-03-30

Publications (1)

Publication Number Publication Date
GB974710A true GB974710A (en) 1964-11-11

Family

ID=25692046

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8504/62A Expired GB974710A (en) 1961-03-14 1962-03-06 Amino-alkylidene-dibenzocycloheptene derivatives

Country Status (7)

Country Link
BE (1) BE615025A (en)
DE (2) DE1288599B (en)
DK (1) DK131902C (en)
ES (1) ES275437A1 (en)
FR (2) FR1320297A (en)
GB (1) GB974710A (en)
SE (1) SE306528B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR182M (en) * 1958-04-03 Hoffmann La Roche

Also Published As

Publication number Publication date
SE306528B (en) 1968-12-02
DK131902C (en) 1976-03-15
DE1768402A1 (en) 1969-10-23
DK131902B (en) 1975-09-22
FR1320297A (en) 1963-03-08
ES275437A1 (en) 1962-10-16
BE615025A (en) 1962-09-13
FR2085M (en) 1963-10-21
DE1288599B (en) 1969-02-06
DE1768402C2 (en) 1983-04-07

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