GB970484A - New 17-desoxy corticosteroids and processes for their preparation - Google Patents
New 17-desoxy corticosteroids and processes for their preparationInfo
- Publication number
- GB970484A GB970484A GB29427/61A GB2942761A GB970484A GB 970484 A GB970484 A GB 970484A GB 29427/61 A GB29427/61 A GB 29427/61A GB 2942761 A GB2942761 A GB 2942761A GB 970484 A GB970484 A GB 970484A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- pregna
- dione
- acyloxy
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000003246 corticosteroid Substances 0.000 title 1
- 229960001334 corticosteroids Drugs 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- PCLIMKBDDGJMGD-UHFFFAOYSA-N N-bromosuccinimide Chemical compound BrN1C(=O)CCC1=O PCLIMKBDDGJMGD-UHFFFAOYSA-N 0.000 abstract 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 abstract 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 abstract 2
- YSIAYLSGHHVHFY-SQQNWLPGSA-N (1S,2S,10S,11S,13R,14S,15S,17S)-14-(2-hydroxyacetyl)-2,13,15-trimethyl-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-5-one Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]23[C@@H]1[C@@H]1C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@@H]3O2 YSIAYLSGHHVHFY-SQQNWLPGSA-N 0.000 abstract 1
- YYROPELSRYBVMQ-UHFFFAOYSA-N 4-toluenesulfonyl chloride Chemical compound CC1=CC=C(S(Cl)(=O)=O)C=C1 YYROPELSRYBVMQ-UHFFFAOYSA-N 0.000 abstract 1
- -1 9a -fluoro-21-substituted - 11b - hydroxy - 16a - methyl - pregna-1, 4 - dien - 3, 20 - diones Chemical class 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000031709 bromination Effects 0.000 abstract 1
- 238000005893 bromination reaction Methods 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 230000022244 formylation Effects 0.000 abstract 1
- 238000006170 formylation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR836012A FR1296544A (fr) | 1960-08-17 | 1960-08-17 | Nouveaux corticostéroïdes 9alpha-fluorés et leur procédé de préparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB970484A true GB970484A (en) | 1964-09-23 |
Family
ID=8737546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB29427/61A Expired GB970484A (en) | 1960-08-17 | 1961-08-15 | New 17-desoxy corticosteroids and processes for their preparation |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE723487A (enEXAMPLES) |
| CH (1) | CH440269A (enEXAMPLES) |
| FR (2) | FR1296544A (enEXAMPLES) |
| GB (1) | GB970484A (enEXAMPLES) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU9201904D0 (en) | 1992-06-09 | 1992-09-28 | Innomedika Szoevetkezet | Laboratorial sem-automatic disclosing appartus operating with microwaves, equipped with teflone dividing and destructor holding devices, int two varieties one with controlled supercooling, another with energy dissipating unit |
-
1960
- 1960-08-17 FR FR836012A patent/FR1296544A/fr not_active Expired
- 1960-11-17 FR FR844189A patent/FR941M/fr active Active
-
1961
- 1961-07-20 CH CH855761A patent/CH440269A/fr unknown
- 1961-08-15 GB GB29427/61A patent/GB970484A/en not_active Expired
-
1968
- 1968-11-06 BE BE723487D patent/BE723487A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR941M (enEXAMPLES) | 1961-11-20 |
| FR1296544A (fr) | 1962-06-22 |
| CH440269A (fr) | 1967-07-31 |
| BE723487A (enEXAMPLES) | 1969-04-16 |
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