GB970027A - Aerosol compositions - Google Patents
Aerosol compositionsInfo
- Publication number
- GB970027A GB970027A GB18354/63A GB1835463A GB970027A GB 970027 A GB970027 A GB 970027A GB 18354/63 A GB18354/63 A GB 18354/63A GB 1835463 A GB1835463 A GB 1835463A GB 970027 A GB970027 A GB 970027A
- Authority
- GB
- United Kingdom
- Prior art keywords
- agent
- alkylene
- substituted
- nitroglycerine
- nitroglycerin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 239000000443 aerosol Substances 0.000 title abstract 3
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 abstract 6
- 229960003711 glyceryl trinitrate Drugs 0.000 abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 5
- 125000002947 alkylene group Chemical group 0.000 abstract 4
- 239000003975 dentin desensitizing agent Substances 0.000 abstract 4
- 239000000006 Nitroglycerin Substances 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 3
- 206010002383 Angina Pectoris Diseases 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- NNPPMTNAJDCUHE-UHFFFAOYSA-N isobutane Chemical compound CC(C)C NNPPMTNAJDCUHE-UHFFFAOYSA-N 0.000 abstract 2
- 239000007921 spray Substances 0.000 abstract 2
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 abstract 1
- POAOYUHQDCAZBD-UHFFFAOYSA-N 2-butoxyethanol Chemical compound CCCCOCCO POAOYUHQDCAZBD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 239000001273 butane Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- HRYZWHHZPQKTII-UHFFFAOYSA-N chloroethane Chemical compound CCCl HRYZWHHZPQKTII-UHFFFAOYSA-N 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229960003750 ethyl chloride Drugs 0.000 abstract 1
- 239000001282 iso-butane Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 abstract 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 abstract 1
- 239000001294 propane Substances 0.000 abstract 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical group CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US197284A US3155574A (en) | 1962-05-24 | 1962-05-24 | Aerosol composition |
Publications (1)
Publication Number | Publication Date |
---|---|
GB970027A true GB970027A (en) | 1964-09-16 |
Family
ID=22728762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB18354/63A Expired GB970027A (en) | 1962-05-24 | 1963-05-09 | Aerosol compositions |
Country Status (5)
Country | Link |
---|---|
US (1) | US3155574A (el) |
BE (1) | BE632504A (el) |
ES (1) | ES300000A3 (el) |
FR (1) | FR2735M (el) |
GB (1) | GB970027A (el) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0133252A1 (de) * | 1983-07-20 | 1985-02-20 | Gödecke Aktiengesellschaft | Zur Inhalation bestimmte Darreichungsform von Calcium-Antagonisten |
WO1986001405A1 (en) * | 1984-08-23 | 1986-03-13 | Kuhlemann & Co. | Pharmaceutical preparation and production process therefor |
EP0288895A1 (de) * | 1987-04-30 | 1988-11-02 | Kali-Chemie Pharma GmbH | Arzneimittelformulierung |
EP0310910A1 (en) * | 1987-09-30 | 1989-04-12 | Nippon Kayaku Kabushiki Kaisha | Nitroglycerin spray |
DE3922650A1 (de) * | 1988-07-08 | 1990-01-11 | Egyt Gyogyszervegyeszeti Gyar | Nitroglycerinhaltige, treibgasfreie aerosolpraeparate und verfahren zu deren herstellung |
WO1993004671A1 (en) * | 1991-09-03 | 1993-03-18 | Minnesota Mining And Manufacturing Company | Medicinal aerosol formulations |
US6197280B1 (en) | 1997-09-09 | 2001-03-06 | Bioglan Laboratories Limited | Pharmaceutical compositions and devices for their administration |
US6413496B1 (en) | 1996-12-04 | 2002-07-02 | Biogland Ireland (R&D) Limited | Pharmaceutical compositions and devices for their administration |
US6491897B1 (en) | 1995-06-27 | 2002-12-10 | Boehringer Ingelheim Kg | Stable pharmaceutical budesonide preparation for producing propellant-free aerosols |
GB2592376A (en) * | 2020-02-25 | 2021-09-01 | Aer Beatha Ltd | Canister |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3445564A (en) * | 1965-01-04 | 1969-05-20 | Ely A Kirschner | Rapidly drying lower aliphatic alcohol-acetone sanitizing composition and method |
US3456052A (en) * | 1965-09-28 | 1969-07-15 | Garrett Lab Inc | Aerosol composition containing butoxymonoether of a polyoxyalkylene glycol |
DE2849074A1 (de) * | 1978-11-11 | 1980-05-14 | Von Treu Ag | Aerosolerzeugnis, verfahren zur herstellung eines aerosolerzeugnisses und vorrichtung zur durchfuehrung des verfahrens |
JPS599539B2 (ja) * | 1979-11-13 | 1984-03-03 | 日本化薬株式会社 | ニトログリセリン水溶液及びその製造法 |
US4581225A (en) * | 1984-04-25 | 1986-04-08 | Eli Lilly And Company | Sustained release intranasal formulation and method of use thereof |
DE4018919C2 (de) * | 1990-06-13 | 1994-08-25 | Sanol Arznei Schwarz Gmbh | Nitroglycerin-Spray |
US5370862A (en) * | 1990-06-13 | 1994-12-06 | Schwarz Pharma Ag | Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina |
DE4026072A1 (de) * | 1990-08-17 | 1992-02-20 | Sanol Arznei Schwarz Gmbh | Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray |
US5869082A (en) * | 1996-04-12 | 1999-02-09 | Flemington Pharmaceutical Corp. | Buccal, non-polar spray for nitroglycerin |
US20030095925A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
US20050180923A1 (en) * | 1997-10-01 | 2005-08-18 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing testosterone |
US20040136914A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
US20050281752A1 (en) * | 1997-10-01 | 2005-12-22 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
US20040136913A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing sumatriptan |
US20030095927A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders |
US20030185761A1 (en) * | 1997-10-01 | 2003-10-02 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
US20050287075A1 (en) * | 1997-10-01 | 2005-12-29 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
US20030095926A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract |
US20030077227A1 (en) | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US20030190286A1 (en) * | 1997-10-01 | 2003-10-09 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma |
US20050163719A1 (en) * | 1997-10-01 | 2005-07-28 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing diazepam |
ES2293875T3 (es) | 1997-10-01 | 2008-04-01 | Novadel Pharma Inc. | Aerosol bucal no polar. |
US20040141923A1 (en) * | 1997-10-01 | 2004-07-22 | Dugger Harry A. | Buccal, polar and non-polar spray containing alprazolam |
US20030077228A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders |
US20040136915A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing atropine |
US7632517B2 (en) * | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
US20050002867A1 (en) * | 1997-10-01 | 2005-01-06 | Novadel Pharma Inc. | Buccal, polar and non-polar sprays containing propofol |
US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
AU2006214166B2 (en) | 2005-02-17 | 2011-09-29 | Zoetis Belgium S.A. | Transmucosal administration of drug compositions for treating and preventing disorders in animals |
GB0602224D0 (en) | 2006-02-03 | 2006-03-15 | Futura Medical Dev Ltd | Composition for promoting vascular smooth muscle relaxation |
CA2649895C (en) * | 2006-04-19 | 2013-03-26 | Novadel Pharma Inc. | Stable hydroalcoholic oral spray formulations and methods |
US20080171089A1 (en) * | 2006-12-22 | 2008-07-17 | Blondino Frank E | Stable anti-nausea oral spray formulations and methods |
BRPI0811430A2 (pt) * | 2007-05-10 | 2015-06-23 | Novadel Pharma Inc | Composições anti-insônia e processos |
DE202008007318U1 (de) | 2008-03-14 | 2008-07-31 | G. Pohl-Boskamp Gmbh & Co. Kg | Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat |
CA2806636C (en) | 2010-08-03 | 2018-01-23 | G. Pohl-Boskamp Gmbh & Co. Kg | Use of glyceryl trinitrate for treating traumatic edema |
ES2672261T3 (es) | 2011-02-25 | 2018-06-13 | G. Pohl-Boskamp Gmbh & Co. Kg | Gránulos estabilizados que contienen trinitrato de glicerilo |
US9248099B2 (en) | 2012-05-31 | 2016-02-02 | Desmoid Aktiengesellschaft | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
HUE033092T2 (hu) | 2012-05-31 | 2017-11-28 | G Pohl-Boskamp Gmbh & Co Kg | Arteriogenezis indukálása nitroglicerinnel mint nitrogén-oxid donorral |
EP2878310B1 (en) | 2013-11-29 | 2017-01-11 | G. Pohl-Boskamp GmbH & Co. KG | Sprayable aqueous composition comprising glyceryl trinitrate |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2648698A (en) * | 1949-07-29 | 1953-08-11 | Hercules Powder Co Ltd | Desensitized liquid explosives |
BE555319A (el) * | 1956-03-21 | 1900-01-01 | ||
BE556587A (el) * | 1957-01-31 | 1957-04-11 |
-
0
- BE BE632504D patent/BE632504A/xx unknown
-
1962
- 1962-05-24 US US197284A patent/US3155574A/en not_active Expired - Lifetime
-
1963
- 1963-05-09 GB GB18354/63A patent/GB970027A/en not_active Expired
- 1963-05-14 FR FR934743A patent/FR2735M/fr not_active Expired
-
1964
- 1964-05-19 ES ES300000A patent/ES300000A3/es not_active Expired
Cited By (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0133252A1 (de) * | 1983-07-20 | 1985-02-20 | Gödecke Aktiengesellschaft | Zur Inhalation bestimmte Darreichungsform von Calcium-Antagonisten |
WO1986001405A1 (en) * | 1984-08-23 | 1986-03-13 | Kuhlemann & Co. | Pharmaceutical preparation and production process therefor |
EP0175671A1 (de) * | 1984-08-23 | 1986-03-26 | Kuhlemann & Co. | Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung |
US4976965A (en) * | 1987-04-30 | 1990-12-11 | Kali-Chemie Pharma Gmbh | Coronary affecting medicinal composition |
EP0288895A1 (de) * | 1987-04-30 | 1988-11-02 | Kali-Chemie Pharma GmbH | Arzneimittelformulierung |
EP0310910A1 (en) * | 1987-09-30 | 1989-04-12 | Nippon Kayaku Kabushiki Kaisha | Nitroglycerin spray |
US4919919A (en) * | 1987-09-30 | 1990-04-24 | Nippon Kayaku Kabushiki Kaisha | Nitroglycerin spray |
GB2220949A (en) * | 1988-07-08 | 1990-01-24 | Egyt Gyogyszervegyeszeti Gyar | Aerosol composition comprising nitroglycerin as active ingredient |
DE3922650A1 (de) * | 1988-07-08 | 1990-01-11 | Egyt Gyogyszervegyeszeti Gyar | Nitroglycerinhaltige, treibgasfreie aerosolpraeparate und verfahren zu deren herstellung |
GB2220949B (en) * | 1988-07-08 | 1992-01-22 | Egyt Gyogyszervegyeszeti Gyar | Aerosol composition comprising nitroglycerin as active ingredient |
AT401613B (de) * | 1988-07-08 | 1996-10-25 | Egyt Gyogyszervegyeszeti Gyar | Nitroglycerinhaltige spray-präparate |
WO1993004671A1 (en) * | 1991-09-03 | 1993-03-18 | Minnesota Mining And Manufacturing Company | Medicinal aerosol formulations |
US6491897B1 (en) | 1995-06-27 | 2002-12-10 | Boehringer Ingelheim Kg | Stable pharmaceutical budesonide preparation for producing propellant-free aerosols |
US8062626B2 (en) | 1995-06-27 | 2011-11-22 | Boehringer Ingelheim Kg | Stable pharmaceutical budesonide preparation for producing propellant-free aerosols |
US6413496B1 (en) | 1996-12-04 | 2002-07-02 | Biogland Ireland (R&D) Limited | Pharmaceutical compositions and devices for their administration |
US6197280B1 (en) | 1997-09-09 | 2001-03-06 | Bioglan Laboratories Limited | Pharmaceutical compositions and devices for their administration |
GB2592376A (en) * | 2020-02-25 | 2021-09-01 | Aer Beatha Ltd | Canister |
Also Published As
Publication number | Publication date |
---|---|
BE632504A (el) | |
FR2735M (fr) | 1964-08-17 |
ES300000A3 (es) | 1964-11-16 |
US3155574A (en) | 1964-11-03 |
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