GB940121A - Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactams - Google Patents

Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactams

Info

Publication number
GB940121A
GB940121A GB1462261A GB1462261A GB940121A GB 940121 A GB940121 A GB 940121A GB 1462261 A GB1462261 A GB 1462261A GB 1462261 A GB1462261 A GB 1462261A GB 940121 A GB940121 A GB 940121A
Authority
GB
United Kingdom
Prior art keywords
phosgene
reaction
lactam
chloroazacyclo
lactams
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1462261A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stamicarbon BV
Original Assignee
Stamicarbon BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stamicarbon BV filed Critical Stamicarbon BV
Publication of GB940121A publication Critical patent/GB940121A/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

In a process for the preparation of a 2-chloroazacyclo-2, 3-alkene-N-carbochloride by reacting in the liquid phase the corresponding o -lactams with phosgene, the lactam being used (1) as such, and while ensuring that at all or substantially all times during the reaction there is an excess of the phosgene over the stoichiometric amount (i.e. a molar ratio of phosgene to lactam of more than 2:1), or (2) as the hydrochloric acid salt, the temperature is maintained at between 115 DEG to 150 DEG C. during at least the latter part of the reaction. The reaction temperature is preferably initially 25 DEG to 90 DEG C. and subsequently 115 DEG to 150 DEG C. Condition (1) may be maintained by feeding the lactam into phosgene or by feeding the phosgene and lactam simultaneously into a reaction vessel. Reaction pressures are preferably 10 to 50 atmospheres. Specification 901,169 also is referred to.
GB1462261A 1960-04-23 1961-04-21 Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactams Expired GB940121A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL250841 1960-04-23

Publications (1)

Publication Number Publication Date
GB940121A true GB940121A (en) 1963-10-23

Family

ID=19752296

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1462261A Expired GB940121A (en) 1960-04-23 1961-04-21 Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactams

Country Status (5)

Country Link
BE (1) BE602883A (en)
CS (1) CS154554B2 (en)
ES (1) ES266734A1 (en)
GB (1) GB940121A (en)
LU (1) LU40046A1 (en)

Also Published As

Publication number Publication date
CS154554B2 (en) 1974-04-30
ES266734A1 (en) 1961-10-01
LU40046A1 (en) 1961-06-21
BE602883A (en) 1961-10-23

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