GB940121A - Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactams - Google Patents
Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactamsInfo
- Publication number
- GB940121A GB940121A GB1462261A GB1462261A GB940121A GB 940121 A GB940121 A GB 940121A GB 1462261 A GB1462261 A GB 1462261A GB 1462261 A GB1462261 A GB 1462261A GB 940121 A GB940121 A GB 940121A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phosgene
- reaction
- lactam
- chloroazacyclo
- lactams
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
In a process for the preparation of a 2-chloroazacyclo-2, 3-alkene-N-carbochloride by reacting in the liquid phase the corresponding o -lactams with phosgene, the lactam being used (1) as such, and while ensuring that at all or substantially all times during the reaction there is an excess of the phosgene over the stoichiometric amount (i.e. a molar ratio of phosgene to lactam of more than 2:1), or (2) as the hydrochloric acid salt, the temperature is maintained at between 115 DEG to 150 DEG C. during at least the latter part of the reaction. The reaction temperature is preferably initially 25 DEG to 90 DEG C. and subsequently 115 DEG to 150 DEG C. Condition (1) may be maintained by feeding the lactam into phosgene or by feeding the phosgene and lactam simultaneously into a reaction vessel. Reaction pressures are preferably 10 to 50 atmospheres. Specification 901,169 also is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL250841 | 1960-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB940121A true GB940121A (en) | 1963-10-23 |
Family
ID=19752296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1462261A Expired GB940121A (en) | 1960-04-23 | 1961-04-21 | Process for the preparation of 2-chloroazacyclo 2.3-alkene-1-carbochlorides from ªÏ-lactams |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE602883A (en) |
| CS (1) | CS154554B2 (en) |
| ES (1) | ES266734A1 (en) |
| GB (1) | GB940121A (en) |
| LU (1) | LU40046A1 (en) |
-
1961
- 1961-04-19 ES ES0266734A patent/ES266734A1/en not_active Expired
- 1961-04-21 BE BE602883A patent/BE602883A/en unknown
- 1961-04-21 LU LU40046D patent/LU40046A1/xx unknown
- 1961-04-21 GB GB1462261A patent/GB940121A/en not_active Expired
- 1961-04-22 CS CS249361A patent/CS154554B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS154554B2 (en) | 1974-04-30 |
| ES266734A1 (en) | 1961-10-01 |
| BE602883A (en) | 1961-10-23 |
| LU40046A1 (en) | 1961-06-21 |
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