GB955087A - Magnesium glutamate hydrobromide and processes for the production thereof - Google Patents
Magnesium glutamate hydrobromide and processes for the production thereofInfo
- Publication number
- GB955087A GB955087A GB38057/60A GB3805760A GB955087A GB 955087 A GB955087 A GB 955087A GB 38057/60 A GB38057/60 A GB 38057/60A GB 3805760 A GB3805760 A GB 3805760A GB 955087 A GB955087 A GB 955087A
- Authority
- GB
- United Kingdom
- Prior art keywords
- magnesium
- hydrobromide
- glutamic acid
- crystallized
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises magnesium glutamate hydrobromide and its monohydrate, and the preparation thereof by (a) neutralizing glutamic acid hydrobromide with magnesium oxide or hydroxide or a basic salt of magnesium (e.g. the carbonate) or (b) neutralizing magnesium glutamate with hydrobromic acid. Starting from glutamic acid itself, these processes may be effected as follows: (a) glutamic acid is reacted with a stiochiometric proportion of hydrobromic acid, the hydrobromide is crystallized at -10 DEG C. and dissolved in water, the pH of the solution is adjusted to as close as possible to 6 by addition of the basic magnesium compound, and magnesium glutamate hydrobromide monohydrate is crystallized slowly therefrom at a temperature below 0 DEG C.; (b) a solution of glutamic acid is adjusted to pH 6.0-6.5 by addition of magnesium oxide or hydroxide or a basic salt of magnesium, filtered and a stoichiometric quantity of hydrobromic acid added slowly to the agitated filtrates and the desired product is thereafter crystallized as in (a).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0253183A ES253183A1 (en) | 1959-11-05 | 1959-11-05 | Magnesium glutamate hydrobromide and processes for the production thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB955087A true GB955087A (en) | 1964-04-15 |
Family
ID=8410837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB38057/60A Expired GB955087A (en) | 1959-11-05 | 1960-11-04 | Magnesium glutamate hydrobromide and processes for the production thereof |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE596742A (en) |
| BR (1) | BR6023941D0 (en) |
| ES (1) | ES253183A1 (en) |
| GB (1) | GB955087A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2660653A1 (en) * | 1990-04-05 | 1991-10-11 | Mayoly Spindler Lab | EQUIMOLAR SALTS OF ALPHA-AMINO DICARBOXYLIC ACID AND DIVALENT METAL, PROCESS FOR PREPARING THEM AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS |
-
1959
- 1959-11-05 ES ES0253183A patent/ES253183A1/en not_active Expired
-
1960
- 1960-11-03 BR BR123941/60A patent/BR6023941D0/en unknown
- 1960-11-04 GB GB38057/60A patent/GB955087A/en not_active Expired
- 1960-11-04 BE BE596742A patent/BE596742A/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2660653A1 (en) * | 1990-04-05 | 1991-10-11 | Mayoly Spindler Lab | EQUIMOLAR SALTS OF ALPHA-AMINO DICARBOXYLIC ACID AND DIVALENT METAL, PROCESS FOR PREPARING THEM AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS |
| WO1991015463A1 (en) * | 1990-04-05 | 1991-10-17 | Laboratoires Mayoly-Spindler | PROCESS FOR PREPARING EQUIMOLAR SALTS OF A DICARBOXYLIC α-AMINO ACID AND A DIVALENT METAL, MAGNESIUM ASPARTATE SALT OBTAINED BY SAID PROCESS AND ITS APPLICATIONS |
Also Published As
| Publication number | Publication date |
|---|---|
| BR6023941D0 (en) | 1973-05-24 |
| ES253183A1 (en) | 1960-06-01 |
| BE596742A (en) | 1961-03-01 |
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