GB931574A - New quinoline compounds - Google Patents
New quinoline compoundsInfo
- Publication number
- GB931574A GB931574A GB41313/61A GB4131361A GB931574A GB 931574 A GB931574 A GB 931574A GB 41313/61 A GB41313/61 A GB 41313/61A GB 4131361 A GB4131361 A GB 4131361A GB 931574 A GB931574 A GB 931574A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- emulsions
- suspensions
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The invention comprises the compound of formula <FORM:0931574/IV(a)/1> and its acid addition salts; and its preparation by reacting 4-hydroxypiperidine with a compound of formula <FORM:0931574/IV(a)/2> wherein X is the acid residue of a reactive ester. The compound can also be prepared by reacting (1) 4-amino-7-chloroquinoline with a compound of formula <FORM:0931574/IV(a)/3> or (2) 4;7-dichloroquinoline with a compound of formula <FORM:0931574/IV(a)/4> and in either case an O-acylated hydroxypiperidyl compound may be used and hydrolysis performed. Pharmaceutical compositions comprise the above compound or a non-toxic acid addition salt thereof together with a pharmaceutical carrier or coating. Compositions for oral (tablets, pills, powders, granules, emulsions, solutions, suspensions, syrups, elixirs and capsules), parenteral (solutions, suspensions, emulsions), and rectal (suppositories) administration are mentioned. The compounds are anti-inflammatory and antirheumatic.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR844524A FR1403605A (en) | 1960-11-21 | 1960-11-21 | New quinoline derivative and its preparation processes |
Publications (1)
Publication Number | Publication Date |
---|---|
GB931574A true GB931574A (en) | 1963-07-17 |
Family
ID=8743108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB41313/61A Expired GB931574A (en) | 1960-11-21 | 1961-11-17 | New quinoline compounds |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH395089A (en) |
FR (2) | FR1403605A (en) |
GB (1) | GB931574A (en) |
-
1960
- 1960-11-21 FR FR844524A patent/FR1403605A/en not_active Expired
-
1961
- 1961-08-10 FR FR870569A patent/FR1691M/en active Active
- 1961-10-16 CH CH1193761A patent/CH395089A/en unknown
- 1961-11-17 GB GB41313/61A patent/GB931574A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CH395089A (en) | 1965-07-15 |
FR1403605A (en) | 1965-06-25 |
FR1691M (en) | 1963-02-11 |
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