GB9309663D0 - Biologically active compounds - Google Patents

Biologically active compounds

Info

Publication number
GB9309663D0
GB9309663D0 GB939309663A GB9309663A GB9309663D0 GB 9309663 D0 GB9309663 D0 GB 9309663D0 GB 939309663 A GB939309663 A GB 939309663A GB 9309663 A GB9309663 A GB 9309663A GB 9309663 D0 GB9309663 D0 GB 9309663D0
Authority
GB
United Kingdom
Prior art keywords
pct
mol
image
residue
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB939309663A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Priority to GB939309663A priority Critical patent/GB9309663D0/en
Publication of GB9309663D0 publication Critical patent/GB9309663D0/en
Priority to AT94913560T priority patent/ATE203414T1/de
Priority to DK94913560T priority patent/DK0649312T3/da
Priority to CN94190242A priority patent/CN1098106C/zh
Priority to EP94913560A priority patent/EP0649312B1/en
Priority to AU65666/94A priority patent/AU671741B2/en
Priority to HU9403811A priority patent/HUT70509A/hu
Priority to ES94913560T priority patent/ES2161764T3/es
Priority to JP6524851A priority patent/JPH08502519A/ja
Priority to US08/351,474 priority patent/US5571785A/en
Priority to PT94913560T priority patent/PT649312E/pt
Priority to PCT/EP1994/001100 priority patent/WO1994026311A1/en
Priority to CA002136438A priority patent/CA2136438C/en
Priority to DE69427799T priority patent/DE69427799T2/de
Priority to UA94129260A priority patent/UA42695C2/uk
Priority to PL94306861A priority patent/PL175325B1/pl
Priority to NZ265266A priority patent/NZ265266A/en
Priority to RU94046336A priority patent/RU2145965C1/ru
Priority to KR1019940704830A priority patent/KR100330635B1/ko
Priority to TW083103180A priority patent/TW268015B/zh
Priority to IL10952894A priority patent/IL109528A/en
Priority to ZA943212A priority patent/ZA943212B/xx
Priority to MYPI94001149A priority patent/MY110974A/en
Priority to FI946128A priority patent/FI112602B/fi
Priority to HU95P/P00250P priority patent/HU211538A9/hu
Priority to GR20010401848T priority patent/GR3036978T3/el
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Polyamides (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
GB939309663A 1993-05-11 1993-05-11 Biologically active compounds Pending GB9309663D0 (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
GB939309663A GB9309663D0 (en) 1993-05-11 1993-05-11 Biologically active compounds
KR1019940704830A KR100330635B1 (ko) 1993-05-11 1994-04-08 안트라사이클린결합체,이의제조방법및이를포함하는약제학적조성물
CA002136438A CA2136438C (en) 1993-05-11 1994-04-08 Anthracycline conjugates, their preparation and their use as antitumor agents
UA94129260A UA42695C2 (uk) 1993-05-11 1994-04-08 Полімерзв'язаний антрациклін, фармацевтична композиція та проміжна сполука
CN94190242A CN1098106C (zh) 1993-05-11 1994-04-08 可溶的合成聚合物结合的蒽环类化合物
EP94913560A EP0649312B1 (en) 1993-05-11 1994-04-08 Anthracycline conjugates, their preparation and their use as antitumor agents
AU65666/94A AU671741B2 (en) 1993-05-11 1994-04-08 Anthracycline conjugates, their preparation and their use as antitumor agents
HU9403811A HUT70509A (en) 1993-05-11 1994-04-08 Anthracycline conjugates, process for their preparation and pharmaceutical compositions contg. them
ES94913560T ES2161764T3 (es) 1993-05-11 1994-04-08 Conjugados de antraciclina, su preparacion y su utilizacion como agente antitumorales.
JP6524851A JPH08502519A (ja) 1993-05-11 1994-04-08 生物学的に活性な化合物
US08/351,474 US5571785A (en) 1993-05-11 1994-04-08 Biologically active compounds
PT94913560T PT649312E (pt) 1993-05-11 1994-04-08 Conjugados de antraciclina processo para a sua preparacao e sua utilizacao como agentes antitumor
PCT/EP1994/001100 WO1994026311A1 (en) 1993-05-11 1994-04-08 Anthracycline conjugates, their preparation and their use as antitumor agents
AT94913560T ATE203414T1 (de) 1993-05-11 1994-04-08 Anthracycline konjugate, deren herstellung und deren verwendung als antitumorwirkstoffe
DE69427799T DE69427799T2 (de) 1993-05-11 1994-04-08 Anthracycline konjugate, deren herstellung und deren verwendung als antitumorwirkstoffe
DK94913560T DK0649312T3 (da) 1993-05-11 1994-04-08 Anthracyclinkonjugater, deres fremstilling og deres anvendelse som antitumormidler
PL94306861A PL175325B1 (pl) 1993-05-11 1994-04-08 Związana z polimerem antracyklina, sposób jej wytwarzania i zawierająca ją kompozycja farmaceutyczna
NZ265266A NZ265266A (en) 1993-05-11 1994-04-08 Anthracycline conjugates, their preparation and use as antitumor agents
RU94046336A RU2145965C1 (ru) 1993-05-11 1994-04-08 Биологически активные полимерсвязанные антрациклины, промежуточные соединения, способы получения и фармацевтическая композиция
TW083103180A TW268015B (https=) 1993-05-11 1994-04-11
IL10952894A IL109528A (en) 1993-05-11 1994-05-03 Polymer-bound anthracyclines their preparation and pharmaceutical compositions containing them
ZA943212A ZA943212B (en) 1993-05-11 1994-05-09 Biologically active compounds.
MYPI94001149A MY110974A (en) 1993-05-11 1994-05-09 Anthracycline conjugates, their preparation and their use as antitumor agents
FI946128A FI112602B (fi) 1993-05-11 1994-12-28 Menetelmä biologisesti aktiivisten polymeerisitoutuneiden antrasykliinien valmistamiseksi
HU95P/P00250P HU211538A9 (en) 1993-05-11 1995-06-19 Biologically active compounds
GR20010401848T GR3036978T3 (en) 1993-05-11 2001-10-22 Anthracycline conjugates, their preparation and their use as antitumor agents.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939309663A GB9309663D0 (en) 1993-05-11 1993-05-11 Biologically active compounds

Publications (1)

Publication Number Publication Date
GB9309663D0 true GB9309663D0 (en) 1993-06-23

Family

ID=10735264

Family Applications (1)

Application Number Title Priority Date Filing Date
GB939309663A Pending GB9309663D0 (en) 1993-05-11 1993-05-11 Biologically active compounds

Country Status (25)

Country Link
US (1) US5571785A (https=)
EP (1) EP0649312B1 (https=)
JP (1) JPH08502519A (https=)
KR (1) KR100330635B1 (https=)
CN (1) CN1098106C (https=)
AT (1) ATE203414T1 (https=)
AU (1) AU671741B2 (https=)
CA (1) CA2136438C (https=)
DE (1) DE69427799T2 (https=)
DK (1) DK0649312T3 (https=)
ES (1) ES2161764T3 (https=)
FI (1) FI112602B (https=)
GB (1) GB9309663D0 (https=)
GR (1) GR3036978T3 (https=)
HU (2) HUT70509A (https=)
IL (1) IL109528A (https=)
MY (1) MY110974A (https=)
NZ (1) NZ265266A (https=)
PL (1) PL175325B1 (https=)
PT (1) PT649312E (https=)
RU (1) RU2145965C1 (https=)
TW (1) TW268015B (https=)
UA (1) UA42695C2 (https=)
WO (1) WO1994026311A1 (https=)
ZA (1) ZA943212B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9320781D0 (en) * 1993-10-08 1993-12-01 Erba Carlo Spa Polymer-bound camptothecin derivatives
GB9721069D0 (en) 1997-10-03 1997-12-03 Pharmacia & Upjohn Spa Polymeric derivatives of camptothecin
GB9721070D0 (en) 1997-10-03 1997-12-03 Pharmacia & Upjohn Spa Bioactive derivatives of camptothecin
EP1401875A4 (en) * 2001-05-04 2005-01-26 Univ Utah Res Found HYALURONIC ACID-CONTAINING BIOKON JUGATES: TARGETED DELIVERY OF ANTIBODIES TO CANCER CELLS
WO2003037915A1 (en) * 2001-10-31 2003-05-08 Biopolymed Inc. Biocompatible polymers including peptide spacer
US20050169883A1 (en) * 2002-05-06 2005-08-04 Prestwich Glenn D. Preblocking with non-ha gags increases effectiveness of ha conjugated anticancer agents
WO2005004805A2 (en) * 2003-07-02 2005-01-20 Solux Corporation Thermally stable crystalline epirubicin hydrochloride and method of making the same
US9737556B2 (en) 2014-06-13 2017-08-22 Trustees Of Tufts College FAP-activated therapeutic agents, and uses related thereto
JP6744826B2 (ja) 2014-06-13 2020-08-19 バック バイオサイエンシーズ, エルエルシーBach BioSciences, LLC Ｆａｐ活性化治療剤及びそれに関連する使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162512A (en) * 1982-03-09 1992-11-10 Cytogen Corporation Amine derivatives of anthracycline antibodies
JPS60246400A (ja) * 1984-05-22 1985-12-06 Ajinomoto Co Inc アントラサイクリン系化合物及び制ガン剤
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
US5169937A (en) * 1986-11-18 1992-12-08 The Scripps Research Institute Method for producing stable glycosylated hemoglobin
DE3722699A1 (de) * 1987-07-09 1989-01-19 Behringwerke Ag Zytostatisch wirksame anthacyclin-konjugate
CA2014244A1 (en) * 1989-04-13 1990-10-13 Takeda Chemical Industries, Ltd. Stabilized composition of anthracyclines
GB9017024D0 (en) * 1990-08-03 1990-09-19 Erba Carlo Spa New linker for bioactive agents
GB9026491D0 (en) * 1990-12-05 1991-01-23 Erba Carlo Spa Anthracycline-conjugates

Also Published As

Publication number Publication date
FI946128A0 (fi) 1994-12-28
KR100330635B1 (ko) 2002-09-17
JPH08502519A (ja) 1996-03-19
EP0649312A1 (en) 1995-04-26
HUT70509A (en) 1995-10-30
CA2136438C (en) 2004-09-14
FI946128A7 (fi) 1994-12-28
NZ265266A (en) 1996-06-25
AU6566694A (en) 1994-12-12
MY110974A (en) 1999-07-31
US5571785A (en) 1996-11-05
UA42695C2 (uk) 2001-11-15
HU211538A9 (en) 1995-12-28
FI112602B (fi) 2003-12-31
CN1108454A (zh) 1995-09-13
EP0649312B1 (en) 2001-07-25
IL109528A (en) 1998-08-16
HU9403811D0 (en) 1995-03-28
RU2145965C1 (ru) 2000-02-27
AU671741B2 (en) 1996-09-05
CA2136438A1 (en) 1994-11-24
ZA943212B (en) 1995-01-18
PL175325B1 (pl) 1998-12-31
PT649312E (pt) 2002-01-30
PL306861A1 (en) 1995-04-18
TW268015B (https=) 1996-01-11
CN1098106C (zh) 2003-01-08
WO1994026311A1 (en) 1994-11-24
KR950702201A (ko) 1995-06-19
IL109528A0 (en) 1994-08-26
ATE203414T1 (de) 2001-08-15
RU94046336A (ru) 1996-10-27
DE69427799T2 (de) 2002-05-02
DK0649312T3 (da) 2001-11-12
GR3036978T3 (en) 2002-01-31
ES2161764T3 (es) 2001-12-16
DE69427799D1 (de) 2001-08-30

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