FI946128A0 - Biologisesti aktiiviset yhdisteet - Google Patents

Biologisesti aktiiviset yhdisteet

Info

Publication number
FI946128A0
FI946128A0 FI946128A FI946128A FI946128A0 FI 946128 A0 FI946128 A0 FI 946128A0 FI 946128 A FI946128 A FI 946128A FI 946128 A FI946128 A FI 946128A FI 946128 A0 FI946128 A0 FI 946128A0
Authority
FI
Finland
Prior art keywords
pct
mol
image
residue
sec
Prior art date
Application number
FI946128A
Other languages
English (en)
Swedish (sv)
Other versions
FI946128A (fi
FI112602B (fi
Inventor
Francesco Angelucci
Maria Grandi
Antonino Suarato
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI946128A publication Critical patent/FI946128A/fi
Publication of FI946128A0 publication Critical patent/FI946128A0/fi
Application granted granted Critical
Publication of FI112602B publication Critical patent/FI112602B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI946128A 1993-05-11 1994-12-28 Menetelmä biologisesti aktiivisten polymeerisitoutuneiden antrasykliinien valmistamiseksi FI112602B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB939309663A GB9309663D0 (en) 1993-05-11 1993-05-11 Biologically active compounds
GB9309663 1993-05-11
EP9401100 1994-04-08
PCT/EP1994/001100 WO1994026311A1 (en) 1993-05-11 1994-04-08 Anthracycline conjugates, their preparation and their use as antitumor agents

Publications (3)

Publication Number Publication Date
FI946128A FI946128A (fi) 1994-12-28
FI946128A0 true FI946128A0 (fi) 1994-12-28
FI112602B FI112602B (fi) 2003-12-31

Family

ID=10735264

Family Applications (1)

Application Number Title Priority Date Filing Date
FI946128A FI112602B (fi) 1993-05-11 1994-12-28 Menetelmä biologisesti aktiivisten polymeerisitoutuneiden antrasykliinien valmistamiseksi

Country Status (25)

Country Link
US (1) US5571785A (fi)
EP (1) EP0649312B1 (fi)
JP (1) JPH08502519A (fi)
KR (1) KR100330635B1 (fi)
CN (1) CN1098106C (fi)
AT (1) ATE203414T1 (fi)
AU (1) AU671741B2 (fi)
CA (1) CA2136438C (fi)
DE (1) DE69427799T2 (fi)
DK (1) DK0649312T3 (fi)
ES (1) ES2161764T3 (fi)
FI (1) FI112602B (fi)
GB (1) GB9309663D0 (fi)
GR (1) GR3036978T3 (fi)
HU (2) HUT70509A (fi)
IL (1) IL109528A (fi)
MY (1) MY110974A (fi)
NZ (1) NZ265266A (fi)
PL (1) PL175325B1 (fi)
PT (1) PT649312E (fi)
RU (1) RU2145965C1 (fi)
TW (1) TW268015B (fi)
UA (1) UA42695C2 (fi)
WO (1) WO1994026311A1 (fi)
ZA (1) ZA943212B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9320781D0 (en) * 1993-10-08 1993-12-01 Erba Carlo Spa Polymer-bound camptothecin derivatives
GB9721069D0 (en) 1997-10-03 1997-12-03 Pharmacia & Upjohn Spa Polymeric derivatives of camptothecin
GB9721070D0 (en) 1997-10-03 1997-12-03 Pharmacia & Upjohn Spa Bioactive derivatives of camptothecin
WO2002090390A1 (en) * 2001-05-04 2002-11-14 University Of Utah Research Foundation Hyaluronic acid containing bioconjugates : targeted delivery of anti-cancer drugs to cancer cells
US7049285B2 (en) * 2001-10-31 2006-05-23 Myung-Ok Park Biocompatible polymers including peptide spacer
CA2483696A1 (en) * 2002-05-06 2003-11-20 University Of Utah Research Foundation Preblocking with non-ha gags increases effectiveness of ha conjugated anticancer agents
IL291922A (en) 2014-06-13 2022-06-01 Tufts College Fap-enabled medical substances and related uses
US9737556B2 (en) 2014-06-13 2017-08-22 Trustees Of Tufts College FAP-activated therapeutic agents, and uses related thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162512A (en) * 1982-03-09 1992-11-10 Cytogen Corporation Amine derivatives of anthracycline antibodies
JPS60246400A (ja) * 1984-05-22 1985-12-06 Ajinomoto Co Inc アントラサイクリン系化合物及び制ガン剤
US5169937A (en) * 1986-11-18 1992-12-08 The Scripps Research Institute Method for producing stable glycosylated hemoglobin
GB9017024D0 (en) * 1990-08-03 1990-09-19 Erba Carlo Spa New linker for bioactive agents

Also Published As

Publication number Publication date
FI946128A (fi) 1994-12-28
AU671741B2 (en) 1996-09-05
IL109528A (en) 1998-08-16
KR100330635B1 (ko) 2002-09-17
US5571785A (en) 1996-11-05
HU211538A9 (en) 1995-12-28
KR950702201A (ko) 1995-06-19
GR3036978T3 (en) 2002-01-31
PT649312E (pt) 2002-01-30
PL306861A1 (en) 1995-04-18
DK0649312T3 (da) 2001-11-12
GB9309663D0 (en) 1993-06-23
JPH08502519A (ja) 1996-03-19
CN1098106C (zh) 2003-01-08
HU9403811D0 (en) 1995-03-28
DE69427799T2 (de) 2002-05-02
TW268015B (fi) 1996-01-11
PL175325B1 (pl) 1998-12-31
EP0649312B1 (en) 2001-07-25
IL109528A0 (en) 1994-08-26
RU2145965C1 (ru) 2000-02-27
ATE203414T1 (de) 2001-08-15
NZ265266A (en) 1996-06-25
CA2136438C (en) 2004-09-14
RU94046336A (ru) 1996-10-27
ES2161764T3 (es) 2001-12-16
AU6566694A (en) 1994-12-12
CN1108454A (zh) 1995-09-13
WO1994026311A1 (en) 1994-11-24
CA2136438A1 (en) 1994-11-24
UA42695C2 (uk) 2001-11-15
DE69427799D1 (de) 2001-08-30
HUT70509A (en) 1995-10-30
FI112602B (fi) 2003-12-31
MY110974A (en) 1999-07-31
ZA943212B (en) 1995-01-18
EP0649312A1 (en) 1995-04-26

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: PHARMACIA & UPJOHN S.P.A.

MA Patent expired