GB925539A - Improvements in or relating to trifluoromethylthiaxanthene and -xanthene derivatives - Google Patents
Improvements in or relating to trifluoromethylthiaxanthene and -xanthene derivativesInfo
- Publication number
- GB925539A GB925539A GB1914062A GB1914062A GB925539A GB 925539 A GB925539 A GB 925539A GB 1914062 A GB1914062 A GB 1914062A GB 1914062 A GB1914062 A GB 1914062A GB 925539 A GB925539 A GB 925539A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trifluoromethyl
- give
- benzoic acid
- xanthene
- xanthenones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LPJDUOFFJNDMLP-UHFFFAOYSA-N 2-(trifluoromethyl)thiopyrano[3,2-b]chromene Chemical compound FC(F)(F)C=1SC2=CC3=CC=CC=C3OC2=CC1 LPJDUOFFJNDMLP-UHFFFAOYSA-N 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 abstract 3
- -1 amino compound Chemical class 0.000 abstract 2
- TXUICONDJPYNPY-UHFFFAOYSA-N (1,10,13-trimethyl-3-oxo-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl) heptanoate Chemical compound C1CC2CC(=O)C=C(C)C2(C)C2C1C1CCC(OC(=O)CCCCCC)C1(C)CC2 TXUICONDJPYNPY-UHFFFAOYSA-N 0.000 abstract 1
- YIXBBFGBWYZPRU-UHFFFAOYSA-N 1-(trifluoromethyl)-9h-xanthene Chemical compound O1C2=CC=CC=C2CC2=C1C=CC=C2C(F)(F)F YIXBBFGBWYZPRU-UHFFFAOYSA-N 0.000 abstract 1
- IEWCYWSKUHXVED-UHFFFAOYSA-N 1-chloro-2-iodo-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=CC=CC(Cl)=C1I IEWCYWSKUHXVED-UHFFFAOYSA-N 0.000 abstract 1
- ZECBOHAXBNGMSP-UHFFFAOYSA-N 1-chloro-2-nitro-3-(trifluoromethyl)benzene Chemical compound [O-][N+](=O)C1=C(Cl)C=CC=C1C(F)(F)F ZECBOHAXBNGMSP-UHFFFAOYSA-N 0.000 abstract 1
- QWBFJJKUZDTEJV-UHFFFAOYSA-N 2-(trifluoromethyl)-2H-thiopyrano[3,2-b]chromen-10-one Chemical class FC(C1SC=2C(C3=CC=CC=C3OC2C=C1)=O)(F)F QWBFJJKUZDTEJV-UHFFFAOYSA-N 0.000 abstract 1
- ZNQWHIGKRQNNAC-UHFFFAOYSA-N 2-[2-(trifluoromethyl)phenyl]sulfanylbenzoic acid Chemical compound OC(=O)C1=CC=CC=C1SC1=CC=CC=C1C(F)(F)F ZNQWHIGKRQNNAC-UHFFFAOYSA-N 0.000 abstract 1
- JZNKIDIWDWFPMC-UHFFFAOYSA-N 2-[2-nitro-3-(trifluoromethyl)phenyl]sulfanylbenzoic acid Chemical compound [N+](=O)([O-])C1=C(C=CC=C1C(F)(F)F)SC1=C(C(=O)O)C=CC=C1 JZNKIDIWDWFPMC-UHFFFAOYSA-N 0.000 abstract 1
- RHZOXQJCQOHUID-UHFFFAOYSA-N 2-chloro-n-(trifluoromethyl)aniline Chemical compound FC(F)(F)NC1=CC=CC=C1Cl RHZOXQJCQOHUID-UHFFFAOYSA-N 0.000 abstract 1
- DMQXDYDKSZTAAJ-UHFFFAOYSA-N 2-phenoxy-3-(trifluoromethyl)benzoic acid Chemical compound OC(=O)C1=CC=CC(C(F)(F)F)=C1OC1=CC=CC=C1 DMQXDYDKSZTAAJ-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 abstract 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 238000003747 Grignard reaction Methods 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910021626 Tin(II) chloride Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- QDLAGTHXVHQKRE-UHFFFAOYSA-N lichenxanthone Natural products COC1=CC(O)=C2C(=O)C3=C(C)C=C(OC)C=C3OC2=C1 QDLAGTHXVHQKRE-UHFFFAOYSA-N 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 229910052987 metal hydride Inorganic materials 0.000 abstract 1
- 150000004681 metal hydrides Chemical class 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 235000011150 stannous chloride Nutrition 0.000 abstract 1
- 239000001119 stannous chloride Substances 0.000 abstract 1
- NBOMNTLFRHMDEZ-UHFFFAOYSA-N thiosalicylic acid Chemical compound OC(=O)C1=CC=CC=C1S NBOMNTLFRHMDEZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940103494 thiosalicylic acid Drugs 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- JNELGWHKGNBSMD-UHFFFAOYSA-N xanthone Chemical class C1=CC=C2C(=O)C3=CC=CC=C3OC2=C1 JNELGWHKGNBSMD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/90—Xanthenes with hydrocarbon radicals, substituted by amino radicals, directly attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
- C07D311/86—Oxygen atoms, e.g. xanthones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12966A US3192204A (en) | 1960-03-07 | 1960-03-07 | Trifluoromethylthiaxanthene and -xanthene derivatives |
| US2693960A | 1960-05-05 | 1960-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB925539A true GB925539A (en) | 1963-05-08 |
Family
ID=26684247
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1914062A Expired GB925539A (en) | 1960-03-07 | 1961-03-03 | Improvements in or relating to trifluoromethylthiaxanthene and -xanthene derivatives |
| GB793161A Expired GB925538A (en) | 1960-03-07 | 1961-03-03 | Improvements in or relating to trifluoromethylthiaxanthene and -xanthene derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB793161A Expired GB925538A (en) | 1960-03-07 | 1961-03-03 | Improvements in or relating to trifluoromethylthiaxanthene and -xanthene derivatives |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE600735A (en:Method) |
| DE (2) | DE1210890B (en:Method) |
| FR (1) | FR1002M (en:Method) |
| GB (2) | GB925539A (en:Method) |
| SE (1) | SE333573B (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0518196A1 (en) * | 1991-06-11 | 1992-12-16 | E.I. Du Pont De Nemours And Company | Polyethers based on 9,9-BIS-perfluoroalkyl-3,6-dihydroxy-xanthene or 9-aryl-9-perfluoroalkyl-3,6-dihydroxy-xanthene |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3159636A (en) * | 1963-07-05 | 1964-12-01 | Searle & Co | 1-amino-4-(xanthenyl and thioxanthenyl) piperazines |
| US3157658A (en) * | 1963-07-05 | 1964-11-17 | Searle & Co | 1-carbalkoxy-4-(9-xanthenyl) piperazines and related compounds |
| US5104858A (en) * | 1988-09-29 | 1992-04-14 | Yale University | Sensitizing multidrug resistant cells to antitumor agents |
| ITMI20032024A1 (it) * | 2003-10-17 | 2005-04-18 | Laboratorio Chimico Int Spa | Procedimento per la preparazione dello z-flupentixol |
| CN1976723B (zh) | 2004-04-30 | 2010-12-29 | Bkg制药有限公司 | 制备治疗或预防感染性疾病的药物的用途 |
| MX2009007235A (es) | 2007-01-05 | 2009-10-16 | Bkg Pharma Aps | "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.". |
| SI2374450T1 (sl) | 2010-04-06 | 2012-09-28 | Lundbeck & Co As H | Sestavki flupentiksola |
| CN104693173B (zh) * | 2015-03-09 | 2018-03-27 | 广东帅广医药有限公司 | 一种盐酸氟哌噻吨的制备方法 |
| CN107987053B (zh) * | 2017-12-08 | 2023-04-14 | 植恩生物技术股份有限公司 | 一种高纯度z型盐酸氟哌噻吨的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1044103B (de) * | 1956-06-12 | 1958-11-20 | Hoffmann La Roche | Verfahren zur Herstellung von Xanthen- bzw. Thioxanthenderivaten |
| AT202143B (de) * | 1956-12-28 | 1959-02-10 | American Cyanamid Co | Verfahren zur Herstellung von neuen Dimethylaminopropylidenxanthenen |
| AT202152B (de) * | 1956-12-28 | 1959-02-10 | American Cyanamid Co | Verfahren zur Herstellung von neuen Dimethylaminopropylidenthiaxanthenen. |
| FR1173489A (fr) * | 1957-04-04 | 1959-02-25 | Merck & Co Inc | Thiaxanthènes substitués |
-
1961
- 1961-02-14 DE DES72528A patent/DE1210890B/de active Pending
- 1961-02-14 DE DE19611518325 patent/DE1518325B1/de active Pending
- 1961-02-28 BE BE600735A patent/BE600735A/fr unknown
- 1961-02-28 FR FR854116A patent/FR1002M/fr active Active
- 1961-03-03 GB GB1914062A patent/GB925539A/en not_active Expired
- 1961-03-03 GB GB793161A patent/GB925538A/en not_active Expired
-
1965
- 1965-08-23 SE SE11002/65A patent/SE333573B/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0518196A1 (en) * | 1991-06-11 | 1992-12-16 | E.I. Du Pont De Nemours And Company | Polyethers based on 9,9-BIS-perfluoroalkyl-3,6-dihydroxy-xanthene or 9-aryl-9-perfluoroalkyl-3,6-dihydroxy-xanthene |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1210890B (de) | 1966-02-17 |
| GB925538A (en) | 1963-05-08 |
| SE333573B (en:Method) | 1971-03-22 |
| BE600735A (fr) | 1961-08-28 |
| DE1518325B1 (de) | 1970-08-27 |
| FR1002M (fr) | 1961-12-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB897328A (en) | Novel tricyclic compounds and a process for the manufacture and conversion thereof | |
| GB925539A (en) | Improvements in or relating to trifluoromethylthiaxanthene and -xanthene derivatives | |
| SE7409654L (en:Method) | ||
| ES551531A0 (es) | Procedimiento para detectar peroxido de hidrogeno o sustancias formadoras de peroxido de hidrogeno | |
| ES8801665A1 (es) | Un procedimiento para la preparacion de derivados de acidos griseolicos. | |
| ES466493A1 (es) | Procedimiento de fabricacion de acidos a-aril-a -oxo-isovalericos. | |
| ES8205215A1 (es) | Un procedimiento para la preparacion de nuevos derivados del acido acetico. | |
| GB931937A (en) | A method of inhibiting reaction between water and small particles of aluminium or aluminium alloys | |
| GB1252618A (en:Method) | ||
| YU47006B (sh) | POSTUPAK ZA PRAVLJENJE 5H-DIBENZ (b,f) AZEPINA | |
| GB1086398A (en) | Aminocoumarin derivatives | |
| Lehmann | La salle sourde du laboratoire d'acoustique du CNET | |
| ES485019A1 (es) | Metodo de descontaminacion del medio ambiente, a base de so-luciones acuosas usadas de catalizador de acetato de cobal- to acetato de manganeso | |
| GR76040B (en:Method) | ||
| GB1033907A (en) | Germicidal available iodine compositions and method for preparing the same | |
| GB847561A (en) | Improvements in or relating to heat protective coatings | |
| ES468314A1 (es) | Un procedimiento para preparar derivados de acido oxazolino-azetidinilpentenoico | |
| GB2004742A (en) | Anti-inflammatory Pharmaceutical Compositions | |
| Kurbanov et al. | The structure of folifinine | |
| Dolya et al. | The oils of four plants | |
| ES291617A1 (es) | Procedimiento para el tratamiento de un hidrogel de óxido metálico | |
| ES308918A1 (es) | Procedimiento para la preparacion de nuevas amidas del acido ariloxiacetico. | |
| BR9809661A (pt) | Redução de halogenetos aromáticos | |
| ES8801906A1 (es) | Procedimiento de produccion de derivados as-triazinos condensados | |
| GB927531A (en) | Substituted benzoquinones and hydroquinones and their preparation |