GB9225492D0 - Amine derivatives - Google Patents

Amine derivatives

Info

Publication number
GB9225492D0
GB9225492D0 GB929225492A GB9225492A GB9225492D0 GB 9225492 D0 GB9225492 D0 GB 9225492D0 GB 929225492 A GB929225492 A GB 929225492A GB 9225492 A GB9225492 A GB 9225492A GB 9225492 D0 GB9225492 D0 GB 9225492D0
Authority
GB
United Kingdom
Prior art keywords
4alkyl
pct
optionally substituted
halogen
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB929225492A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to GB929225492A priority Critical patent/GB9225492D0/en
Publication of GB9225492D0 publication Critical patent/GB9225492D0/en
Priority to TW082110143A priority patent/TW237450B/zh
Priority to KR1019950702269A priority patent/KR950704270A/ko
Priority to HU9501622A priority patent/HUT71339A/hu
Priority to AT94902658T priority patent/ATE168102T1/de
Priority to PL93309281A priority patent/PL309281A1/xx
Priority to EP94902658A priority patent/EP0672037B1/en
Priority to AU56948/94A priority patent/AU688295B2/en
Priority to DE69319614T priority patent/DE69319614D1/de
Priority to JP6513738A priority patent/JPH08504200A/ja
Priority to RU95114528/04A priority patent/RU95114528A/ru
Priority to RO95-01064A priority patent/RO114446B1/ro
Priority to PCT/EP1993/003381 priority patent/WO1994013648A1/en
Priority to CZ951384A priority patent/CZ138495A3/cs
Priority to NZ258874A priority patent/NZ258874A/en
Priority to BR9307580A priority patent/BR9307580A/pt
Priority to CA002150461A priority patent/CA2150461A1/en
Priority to US08/446,728 priority patent/US5569654A/en
Priority to SK741-95A priority patent/SK74195A3/sk
Priority to MX9307654A priority patent/MX9307654A/es
Priority to IL10786993A priority patent/IL107869A/en
Priority to ZA939068A priority patent/ZA939068B/xx
Priority to CN93120779A priority patent/CN1093085A/zh
Priority to EC1994001085A priority patent/ECSP941085A/es
Priority to PE1994243670A priority patent/PE54294A1/es
Priority to OA60669A priority patent/OA10161A/en
Priority to BG99696A priority patent/BG99696A/bg
Priority to NO952208A priority patent/NO952208L/no
Priority to FI952709A priority patent/FI952709A7/fi
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB929225492A 1992-12-05 1992-12-05 Amine derivatives Pending GB9225492D0 (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
GB929225492A GB9225492D0 (en) 1992-12-05 1992-12-05 Amine derivatives
TW082110143A TW237450B (https=) 1992-12-05 1993-12-01
SK741-95A SK74195A3 (en) 1992-12-05 1993-12-02 Amine derivatives, method of their production, their use for production of pharmaceutical agents and pharmaceutical agents with their contents
NZ258874A NZ258874A (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives, preparation and use as pharmaceuticals
BR9307580A BR9307580A (pt) 1992-12-05 1993-12-02 Compostos processo para a preparação dos mesmos composições farmacêuticas uso de um composto e processo de tratamento de um mamífero que inclui o ser humano
AT94902658T ATE168102T1 (de) 1992-12-05 1993-12-02 1,4-benzodiazepinderivate und ihre verwendung als cck-modulatoren
PL93309281A PL309281A1 (en) 1992-12-05 1993-12-02 Derivatives of 1,4-benzodiazepine and their application as cck modulators
EP94902658A EP0672037B1 (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives and their use as cck-modulators
AU56948/94A AU688295B2 (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives and their use as CCK-modulators
DE69319614T DE69319614D1 (de) 1992-12-05 1993-12-02 1,4-benzodiazepinderivate und ihre verwendung als cck-modulatoren
JP6513738A JPH08504200A (ja) 1992-12-05 1993-12-02 １，４‐ベンゾジアゼピン誘導体およびｃｃｋ‐調節剤としてのその用途
RU95114528/04A RU95114528A (ru) 1992-12-05 1993-12-02 Аминопроизводные, способ получения, фармацевтическая композиция способ лечения
RO95-01064A RO114446B1 (ro) 1992-12-05 1993-12-02 Derivati de 5-aminoalchil-1,4-benzodiazepina si procedee pentru prepararea acestora
PCT/EP1993/003381 WO1994013648A1 (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives and their use as cck-modulators
CZ951384A CZ138495A3 (en) 1992-12-05 1993-12-02 Amine derivatives, process of their preparation, their use for preparing pharmaceutical preparations and the pharmaceutical compositions containing thereof
KR1019950702269A KR950704270A (ko) 1992-12-05 1993-12-02 1, 4-벤조디아제핀 유도체 및 그의 CCK조절제로서의 용도 (1, 4-Benzodiazepine Derivatives and Their Use as CCK―Modulators)
HU9501622A HUT71339A (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives and pharmaceutical compositions containing them
CA002150461A CA2150461A1 (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives and their use as cck-modulators
US08/446,728 US5569654A (en) 1992-12-05 1993-12-02 Benzodiazepinones
ZA939068A ZA939068B (en) 1992-12-05 1993-12-03 Amine derivatives
MX9307654A MX9307654A (es) 1992-12-05 1993-12-03 Derivados de amina, proceso para su preparacion y composicion farmaceutica que los contiene.
IL10786993A IL107869A (en) 1992-12-05 1993-12-03 Benzodiazepine derivatives their preparation and pharmaceutical compositions containing them
CN93120779A CN1093085A (zh) 1992-12-05 1993-12-04 胺衍生物
EC1994001085A ECSP941085A (es) 1992-12-05 1994-05-11 Derivados de amida, proceso para su preparacion y composicion farmaceuticas que los contiene
PE1994243670A PE54294A1 (es) 1992-12-05 1994-06-01 Derivado de 5-aminoalquil-1,4-benzodiazepina
OA60669A OA10161A (en) 1992-12-05 1995-05-30 Amine derivatives
BG99696A BG99696A (bg) 1992-12-05 1995-06-02 Производни на 1,4-бензодиазепин,методи за тяхното получаване, съдържащи ги фармацевтични състави,използването им като сск- модулатори и метод за лечение на състояния,модулирани от сск
NO952208A NO952208L (no) 1992-12-05 1995-06-02 Amin-derivater
FI952709A FI952709A7 (fi) 1992-12-05 1995-06-02 1,4-bentsodiatsepiinijohdannaisia ja niiden käyttö cck-modulaattoreina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929225492A GB9225492D0 (en) 1992-12-05 1992-12-05 Amine derivatives

Publications (1)

Publication Number Publication Date
GB9225492D0 true GB9225492D0 (en) 1993-01-27

Family

ID=10726205

Family Applications (1)

Application Number Title Priority Date Filing Date
GB929225492A Pending GB9225492D0 (en) 1992-12-05 1992-12-05 Amine derivatives

Country Status (29)

Country Link
US (1) US5569654A (https=)
EP (1) EP0672037B1 (https=)
JP (1) JPH08504200A (https=)
KR (1) KR950704270A (https=)
CN (1) CN1093085A (https=)
AT (1) ATE168102T1 (https=)
AU (1) AU688295B2 (https=)
BG (1) BG99696A (https=)
BR (1) BR9307580A (https=)
CA (1) CA2150461A1 (https=)
CZ (1) CZ138495A3 (https=)
DE (1) DE69319614D1 (https=)
EC (1) ECSP941085A (https=)
FI (1) FI952709A7 (https=)
GB (1) GB9225492D0 (https=)
HU (1) HUT71339A (https=)
IL (1) IL107869A (https=)
MX (1) MX9307654A (https=)
NO (1) NO952208L (https=)
NZ (1) NZ258874A (https=)
OA (1) OA10161A (https=)
PE (1) PE54294A1 (https=)
PL (1) PL309281A1 (https=)
RO (1) RO114446B1 (https=)
RU (1) RU95114528A (https=)
SK (1) SK74195A3 (https=)
TW (1) TW237450B (https=)
WO (1) WO1994013648A1 (https=)
ZA (1) ZA939068B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314981D0 (en) * 1993-07-20 1993-09-01 Glaxo Spa Chemical compounds
US5428157A (en) * 1993-11-22 1995-06-27 Merck & Co., Inc. 3-acylaminobenzodiazepines
JPH09511998A (ja) * 1994-04-15 1997-12-02 グラクソ、ウェルカム、インコーポレーテッド １，４ − ベンゾジアゼピン化合物を用いたコレシストキニンアゴニスト活性の誘導方法
US5807876A (en) * 1996-04-23 1998-09-15 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme
AUPO284396A0 (en) * 1996-10-08 1996-10-31 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
NZ500352A (en) 1997-04-14 2001-10-26 Cor Therapeutics Inc Cyclic diaza selective factor Xa inhibitors
AU747531B2 (en) 1997-04-14 2002-05-16 Millennium Pharmaceuticals, Inc. Selective factor Xa inhibitors
US6204268B1 (en) 1997-04-14 2001-03-20 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6333321B1 (en) * 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6100254A (en) * 1997-10-10 2000-08-08 Board Of Regents, The University Of Texas System Inhibitors of protein tyrosine kinases
ATE357228T1 (de) * 2001-05-25 2007-04-15 Cephalon Inc Feste pharmazeutische formulierung enthaltend modafinil
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
JP2008523071A (ja) * 2004-12-07 2008-07-03 ルーカス ファーマシューティカルズ， インコーポレイテッド Ｍａｐキナーゼの尿素インヒビター
EP1824843A2 (en) * 2004-12-07 2007-08-29 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
CA2635888A1 (en) * 2006-01-04 2007-07-19 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
GB201414116D0 (en) * 2014-08-08 2014-09-24 Trio Medicines Ltd Benzodiazepine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032226A1 (en) * 1989-12-18 1991-06-19 Mark G. Bock Benzodiazepine analogs
CA2068355A1 (en) * 1991-05-14 1992-11-15 Mark S. Chambers Benzodiazephine derivatives, compositions containing them and their use in therapy
GB9201180D0 (en) * 1992-01-21 1992-03-11 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
MX9307654A (es) 1994-06-30
CA2150461A1 (en) 1994-06-23
EP0672037B1 (en) 1998-07-08
RU95114528A (ru) 1997-06-10
OA10161A (en) 1996-12-18
PE54294A1 (es) 1995-01-06
JPH08504200A (ja) 1996-05-07
IL107869A0 (en) 1994-04-12
ECSP941085A (es) 1994-12-15
TW237450B (https=) 1995-01-01
AU5694894A (en) 1994-07-04
ZA939068B (en) 1994-08-09
BR9307580A (pt) 1999-06-29
US5569654A (en) 1996-10-29
AU688295B2 (en) 1998-03-12
CZ138495A3 (en) 1995-12-13
BG99696A (bg) 1996-01-31
WO1994013648A1 (en) 1994-06-23
FI952709A0 (fi) 1995-06-02
CN1093085A (zh) 1994-10-05
NO952208D0 (no) 1995-06-02
KR950704270A (ko) 1995-11-17
ATE168102T1 (de) 1998-07-15
SK74195A3 (en) 1995-11-08
DE69319614D1 (de) 1998-08-13
RO114446B1 (ro) 1999-04-30
EP0672037A1 (en) 1995-09-20
NZ258874A (en) 1996-09-25
FI952709A7 (fi) 1995-08-01
IL107869A (en) 1998-10-30
NO952208L (no) 1995-08-02
PL309281A1 (en) 1995-10-02
HU9501622D0 (en) 1995-08-28
HUT71339A (en) 1995-11-28

Similar Documents

Publication Publication Date Title
TW237450B (https=)
CO4970780A1 (es) Nuevos compuestos heterociclicos de piridazina
DK0590919T3 (da) Terapeutiske midler mod Parkinsons sygdom
UA72917C2 (en) Cyclic carbamates derivatives, pharmaceutical composition containing said derivatives of cyclic carbamates and active ingredients as modulators of the progesterone receptor
NZ503076A (en) 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid derivatives and addition salts thereof, with antagonism against amino acid receptors (particularly AMPA receptor) and processes for their preparation
IL104567A (en) Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
UY24802A1 (es) Nuevos compuestos
BG97221A (bg) Ортозаместени бифениламидини и бифенилизанидини и съдържащите ги антидиабетични или хипогликемични средства
DK0759027T3 (da) Bicykliske amidinderivater som inhibitorer af nitrogenoxidsynthetase
MY118638A (en) 1,5-benzodiazepine derivatives
ATE236636T1 (de) Hexahydro-pyrido (4,3-b)indolderivate als antipsychotische arzneimittel
CO5540322A2 (es) Nuevos derivados heterociclicos que comprenden un anillo de tetrahidroisoquinolina y uso farmaceutico de los mismos
DE69520279D1 (de) Bibphenylamid-derivate als 5-ht1d-antagonisten
ATE172454T1 (de) Pyridazinon derivate mit pharmazeutischer wirkung
FR2632639B1 (fr) Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent
NO961404L (no) 4-indolylpiperazinyl-derivater
ES2010089A6 (es) Procedimiento para la obtencion de n-oxidos de gamma-carbolina antipsicoticos.
DE69414117D1 (de) 1,5-benzodiazepin-derivate verwendbar als cck oder gastrin antagonisten
HUT65376A (en) Process for preparing n,n',n-trisubstituted 5-(diamino-methylene)-1,3-dioxane-4,6-diones and pharmaceutical compositions containing them as active ingredient
HK1043991A1 (zh) 作為黃體酮受體調節劑的喹唑啉酮及苯並噁嗪衍生物
TH15971A (th) อนุพันธ์ของแอมีน
ECSP920822A (es) Composiciones heterocyclicas
MX9710378A (es) Derivados de 4-finilaminotiazol, su proceso de preparacion y las composiciones farmaceuticas que los contienen.