GB908737A - 6-oxygenated pregnane compounds - Google Patents

6-oxygenated pregnane compounds

Info

Publication number
GB908737A
GB908737A GB2088460A GB2088460A GB908737A GB 908737 A GB908737 A GB 908737A GB 2088460 A GB2088460 A GB 2088460A GB 2088460 A GB2088460 A GB 2088460A GB 908737 A GB908737 A GB 908737A
Authority
GB
United Kingdom
Prior art keywords
steroids
hydrogen
formula
group
ch3b
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2088460A
Inventor
Vladimir Petrow
George Oliver Weston
David Morton Williamson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BDH Chemicals Ltd
Original Assignee
BDH Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BDH Chemicals Ltd filed Critical BDH Chemicals Ltd
Priority to GB2088460A priority Critical patent/GB908737A/en
Publication of GB908737A publication Critical patent/GB908737A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises (1) a process for the preparation of steroids of the formula <FORM:0908737/IV (b)/1> (wherein R11 is an acyl group containing up to 10 carbon atoms, R is oxygen, a hydroxyl group and a hydrogen atom or a hydroxyl group and a methyl or ethyl group, and R1 is two hydrogen atoms or a methylidene or ethylidene group) by reacting steroids of the formula <FORM:0908737/IV (b)/2> (where R is hydrogen, methyl or ethyl) with an organic peracid in an inert organic solvent, to give the 6-hydroxy-steroids and, if desired, when R is hydrogen, oxidizing these to the 6-keto-steroids; and (2) steroids of the first formula above having the following values for R, R1 and R11:- (a) R=a CH3b OH, R1=H2, R11=Ac; (b) R=a OHb CH3, R1=H2, R11=Ac; (c) R=a Hb OH, R1=CH2, R11=Ac; (d) R=a CH3b OH, R1=CH2, R11=Ac; and (e) R=O, R1=CH2, R11=Ac. Examples are given. Steroids of the second formula above are prepared by treating the corresponding pregn-4-en-3-ones with acetic anhydride in presence of toluene-p-sulphonic acid. U.S.A. Specification 2,889,342 is referred to. p
GB2088460A 1960-06-14 1960-06-14 6-oxygenated pregnane compounds Expired GB908737A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2088460A GB908737A (en) 1960-06-14 1960-06-14 6-oxygenated pregnane compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2088460A GB908737A (en) 1960-06-14 1960-06-14 6-oxygenated pregnane compounds

Publications (1)

Publication Number Publication Date
GB908737A true GB908737A (en) 1962-10-24

Family

ID=10153382

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2088460A Expired GB908737A (en) 1960-06-14 1960-06-14 6-oxygenated pregnane compounds

Country Status (1)

Country Link
GB (1) GB908737A (en)

Similar Documents

Publication Publication Date Title
GB1048231A (en) New steroid compounds, compositions incorporating them and processes for their preparation
ES301833A1 (en) A procedure for the preparation of 19-alkil-steroids (Machine-translation by Google Translate, not legally binding)
GB908737A (en) 6-oxygenated pregnane compounds
GB933867A (en) Fluorinated steroids
GB1147803A (en) Improvements in or relating to novel steroids and the manufacture thereof
GB1075545A (en) Improvements in or relating to steroids and the manufacture thereof
ES417737A1 (en) Steroids of the pregnane series
GB1084759A (en) Steroid compounds
US3324152A (en) 1alpha-methyl-delta2-androstenes
GB1530043A (en) Organic peroxides
GB1084467A (en) Improvements in or relating to steroids and the manufacture thereof
GB886964A (en) Improvements in or relating to steroids and the manufacture thereof
Crundwell et al. Synthesis of Fatty Acids with Smooth Muscle Stimulant Activity. II. Myristoylbutyrolactones and Analogs
GB967080A (en) Novel steroid compounds and process for the preparation thereof
ES428225A1 (en) Process for the preparation of 17{62 -oxalyl steroids
GB1003305A (en) Novel steroid compounds and their preparation
GB1120478A (en) Improvements in or relating to steroids and the manufacture thereof
GB852684A (en) 6-methyl steroid compounds
GB1018780A (en) Steroid (2,3í¬c) furazan compounds and the process for the production thereof
GB855716A (en) Long-acting steroid compounds
GB1086461A (en) 1,1-ethylene-17ª‡-alkyl-í¸-5ª‡-androsten-17ª‰-ols and their 17-esters and a process for their manufacture
GB1014155A (en) New estrene derivatives and processes for the preparation and use thereof
GB934713A (en) New steroid compounds and processes for their preparation
GB872316A (en) Improvements in or relating to steroids
ES401765A1 (en) 17beta-tetrahydropyran-4-yloxy- steroids