GB881827A - 7-methyl-morpholyl-theophylline and process for the preparation thereof - Google Patents
7-methyl-morpholyl-theophylline and process for the preparation thereofInfo
- Publication number
- GB881827A GB881827A GB28574/60A GB2857460A GB881827A GB 881827 A GB881827 A GB 881827A GB 28574/60 A GB28574/60 A GB 28574/60A GB 2857460 A GB2857460 A GB 2857460A GB 881827 A GB881827 A GB 881827A
- Authority
- GB
- United Kingdom
- Prior art keywords
- theophylline
- morpholyl
- methyl
- preparation
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises 7-methyl-morpholyl-theophylline having the formula <FORM:0881827/IV (b)/1> said compound being a white powder which is soluble in water, only poorly soluble in alcohol and practically insoluble in ether and having a m.p. within the range 174 DEG C.-177 DEG C. and the preparation thereof by suspending thiophylline in an alcohol, adding thereto a substantially equimolecular quantity of morpholine with agitation, then slowly adding formalin, separating any theophylline remaining in suspension, allowing the solution to stand at ordinary temperature, cooling this solution to precipitate the product which is then filtered off, drained and washed first with ethanol and then with acetone, and finally air-drying the washed residue.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR881827X | 1959-08-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB881827A true GB881827A (en) | 1961-11-08 |
Family
ID=9373771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB28574/60A Expired GB881827A (en) | 1959-08-27 | 1960-08-17 | 7-methyl-morpholyl-theophylline and process for the preparation thereof |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB881827A (en) |
-
1960
- 1960-08-17 GB GB28574/60A patent/GB881827A/en not_active Expired
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