GB881827A - 7-methyl-morpholyl-theophylline and process for the preparation thereof - Google Patents

7-methyl-morpholyl-theophylline and process for the preparation thereof

Info

Publication number
GB881827A
GB881827A GB28574/60A GB2857460A GB881827A GB 881827 A GB881827 A GB 881827A GB 28574/60 A GB28574/60 A GB 28574/60A GB 2857460 A GB2857460 A GB 2857460A GB 881827 A GB881827 A GB 881827A
Authority
GB
United Kingdom
Prior art keywords
theophylline
morpholyl
methyl
preparation
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB28574/60A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB881827A publication Critical patent/GB881827A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises 7-methyl-morpholyl-theophylline having the formula <FORM:0881827/IV (b)/1> said compound being a white powder which is soluble in water, only poorly soluble in alcohol and practically insoluble in ether and having a m.p. within the range 174 DEG C.-177 DEG C. and the preparation thereof by suspending thiophylline in an alcohol, adding thereto a substantially equimolecular quantity of morpholine with agitation, then slowly adding formalin, separating any theophylline remaining in suspension, allowing the solution to stand at ordinary temperature, cooling this solution to precipitate the product which is then filtered off, drained and washed first with ethanol and then with acetone, and finally air-drying the washed residue.
GB28574/60A 1959-08-27 1960-08-17 7-methyl-morpholyl-theophylline and process for the preparation thereof Expired GB881827A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR881827X 1959-08-27

Publications (1)

Publication Number Publication Date
GB881827A true GB881827A (en) 1961-11-08

Family

ID=9373771

Family Applications (1)

Application Number Title Priority Date Filing Date
GB28574/60A Expired GB881827A (en) 1959-08-27 1960-08-17 7-methyl-morpholyl-theophylline and process for the preparation thereof

Country Status (1)

Country Link
GB (1) GB881827A (en)

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