GB866815A - Piperazine salts - Google Patents

Piperazine salts

Info

Publication number
GB866815A
GB866815A GB13017/58A GB1301758A GB866815A GB 866815 A GB866815 A GB 866815A GB 13017/58 A GB13017/58 A GB 13017/58A GB 1301758 A GB1301758 A GB 1301758A GB 866815 A GB866815 A GB 866815A
Authority
GB
United Kingdom
Prior art keywords
acid
piperazine
salt
chlorobenzhydryl
hydroxynaphthalene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13017/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB866815A publication Critical patent/GB866815A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises the 1,11-methylenebis-(2-hydroxynaphthalene-3-carboxylic acid) acid addition salt of N-p-chlorobenzhydryl-N1-(2-hydroxyethoxyethyl)-piperazine, wherein the acid and base components are present in an equimolar ratio and the preparation thereof by reacting a N-p-chlorobenzhydryl-N1-(2-hydroxyethoxyethyl)-piperazine diacid salt in an aqueous solvent medium with an equimolar amount of a 1,1-methylene-bis-(2-hydroxynaphthalene-3-carboxylic acid) dibase salt or by reacting the base component or a diacid salt thereof, in an inert, polar solvent with an equimolar amount of the acid component. Reference has been directed by the Comptroller to Specification 817,231.ALSO:Pharmaceutical compositions comprise the 1,11 - methylene - bis - (2 - hydroxynaphthalene-3-carboxylic acid) acid addition salt of N - p - chlorobenzhydryl - N1 - (2 - hydroxyethoxy ethyl)-piperazine wherein the acid and base components are present in an equimolar ratio, together with a pharmaceutically acceptable carrier. The compositions may be in the form of tablets, capsules or elixirs. Reference has been directed by the Comptroller to Specification 817,231.
GB13017/58A 1957-06-14 1958-04-24 Piperazine salts Expired GB866815A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US866815XA 1957-06-14 1957-06-14

Publications (1)

Publication Number Publication Date
GB866815A true GB866815A (en) 1961-05-03

Family

ID=22200169

Family Applications (1)

Application Number Title Priority Date Filing Date
GB13017/58A Expired GB866815A (en) 1957-06-14 1958-04-24 Piperazine salts

Country Status (2)

Country Link
DE (1) DE1129493B (en)
GB (1) GB866815A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001517674A (en) * 1997-09-22 2001-10-09 アヴェンティス・リサーチ・ウント・テクノロジーズ・ゲーエムベーハー・ウント・コー・カーゲー Pentopyranosyl nucleosides, their production and use

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001517674A (en) * 1997-09-22 2001-10-09 アヴェンティス・リサーチ・ウント・テクノロジーズ・ゲーエムベーハー・ウント・コー・カーゲー Pentopyranosyl nucleosides, their production and use
JP2001517676A (en) * 1997-09-22 2001-10-09 アヴェンティス・リサーチ・ウント・テクノロジーズ・ゲーエムベーハー・ウント・コー・カーゲー Use of pentopyranosyl nucleosides for making electronic components and pentopyranosyl nucleoside conjugates
JP2001517675A (en) * 1997-09-22 2001-10-09 アヴェンティス・リサーチ・ウント・テクノロジーズ・ゲーエムベーハー・ウント・コー・カーゲー Method for producing pentopyranosyl nucleoside
JP4674965B2 (en) * 1997-09-22 2011-04-20 ナノジェン・レコグノミクス・ゲーエムベーハー Use of pentopyranosyl nucleosides to produce electronic components and pentopyranosyl nucleoside conjugates
JP4674964B2 (en) * 1997-09-22 2011-04-20 ナノジェン・レコグノミクス・ゲーエムベーハー Pentopyranosyl nucleoside, its manufacture and use

Also Published As

Publication number Publication date
DE1129493B (en) 1962-05-17

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