GB1172800A - Novel N-Pyridylmethylidene-Homocysteine Thiolactone Compound and the preparation thereof - Google Patents

Novel N-Pyridylmethylidene-Homocysteine Thiolactone Compound and the preparation thereof

Info

Publication number
GB1172800A
GB1172800A GB47811/68A GB4781168A GB1172800A GB 1172800 A GB1172800 A GB 1172800A GB 47811/68 A GB47811/68 A GB 47811/68A GB 4781168 A GB4781168 A GB 4781168A GB 1172800 A GB1172800 A GB 1172800A
Authority
GB
United Kingdom
Prior art keywords
pyridylmethylidene
homocysteine
novel
preparation
homocysteine thiolactone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB47811/68A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of GB1172800A publication Critical patent/GB1172800A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,172,800. Pyridoxal derivatives. TANABE SEIYAKU CO. Ltd. 9 Oct., 1968, [16 Oct., 1967], No. 47811/68. Heading C2V. The invention comprises N-(2-methyl-3- hydroxy - 5 - hydroxymethyl - 4 - pyridylmethylidene) - homocysteine tiolactone of formula and acid addition salts thereof. The compound, which has both vitamin B 6 and homocysteine activity, is prepared by reacting pyridoxal and an acid addition salt of homocysteine thiolactone in a solvent. Examples are given.
GB47811/68A 1967-10-16 1968-10-09 Novel N-Pyridylmethylidene-Homocysteine Thiolactone Compound and the preparation thereof Expired GB1172800A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6641667 1967-10-16

Publications (1)

Publication Number Publication Date
GB1172800A true GB1172800A (en) 1969-12-03

Family

ID=13315152

Family Applications (1)

Application Number Title Priority Date Filing Date
GB47811/68A Expired GB1172800A (en) 1967-10-16 1968-10-09 Novel N-Pyridylmethylidene-Homocysteine Thiolactone Compound and the preparation thereof

Country Status (5)

Country Link
US (1) US3632806A (en)
CH (1) CH507981A (en)
DE (1) DE1802162A1 (en)
FR (1) FR7972M (en)
GB (1) GB1172800A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417204B1 (en) 2000-07-07 2002-07-09 Medicure International Inc. Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6605612B2 (en) 2000-02-29 2003-08-12 Medicure International Inc. Cardioprotective phosohonates and malonates
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125616A (en) * 1975-11-04 1978-11-14 Zambeletti Espana, S.A. Pyridoxylidine amino benzoate compounds
JP2008505126A (en) * 2004-07-07 2008-02-21 メディキュア インターナショナル インコーポレイテッド Combination therapy using platelet aggregating drugs
CA2585165A1 (en) * 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
US7459468B2 (en) * 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
US20060094749A1 (en) * 2004-10-28 2006-05-04 Medicure International Inc. Substituted pyridoxines as anti-platelet agents
CA2632090A1 (en) * 2005-11-28 2007-05-31 Medicure International Inc. Selected dosage for the treatment of cardiovascular and related pathologies

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605612B2 (en) 2000-02-29 2003-08-12 Medicure International Inc. Cardioprotective phosohonates and malonates
US6667315B2 (en) 2000-02-29 2003-12-23 Medicure International Inc. Cardioprotective phosphonates and malonates
US6780997B2 (en) 2000-02-29 2004-08-24 Medicure International Inc. Cardioprotective phosphonates and malonates
US6867215B2 (en) 2000-02-29 2005-03-15 Medicure International Inc. Cardioprotective phosphonates and malonates
US7105673B2 (en) 2000-02-29 2006-09-12 Medicure International Inc. Cardioprotective phosphonates and malonates
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6861439B2 (en) 2000-03-28 2005-03-01 Medicure International, Inc. Treatment of cerebrovascular disease
US6417204B1 (en) 2000-07-07 2002-07-09 Medicure International Inc. Pyridoxine AMD pyridoxal analogues: cardiovascular therapeutics
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses

Also Published As

Publication number Publication date
DE1802162A1 (en) 1969-04-30
CH507981A (en) 1971-05-31
FR7972M (en) 1970-06-01
US3632806A (en) 1972-01-04

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees