GB843993A - Improvements in or relating to the preparation of 3:5-diketo-pyrazolidine derivatives - Google Patents

Improvements in or relating to the preparation of 3:5-diketo-pyrazolidine derivatives

Info

Publication number
GB843993A
GB843993A GB16175/58A GB1617558A GB843993A GB 843993 A GB843993 A GB 843993A GB 16175/58 A GB16175/58 A GB 16175/58A GB 1617558 A GB1617558 A GB 1617558A GB 843993 A GB843993 A GB 843993A
Authority
GB
United Kingdom
Prior art keywords
general formula
derivative
alkyl
condensing
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB16175/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB843993A publication Critical patent/GB843993A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

3:5 - Dioxopyrazolidine derivatives of the general formula: <FORM:0843993/IV(b)/1> (Wherein R11 represents a C1-6 alkyl radical, R12 represents hydrogen or an alkyl, aryl or acyl radical, and R13 and R14 represent alkyl, aryl or aralkyl radicals, with the proviso that R11, R12, R13 and R14 need not be dissimilar) are produced by condensing a 3 : 5 - dioxopyrazolidine derivative of the general formula: <FORM:0843993/IV(b)/2> with a 4 - halopiperidine derivative of the general formula: <FORM:0843993/IV(b)/3> (wherein X represents a halogen atom). Where R12 in the starting material II is an acyl radical, this may be split off during or after the condensation to give an end product in which R12 is hydrogen. The products form salts with organic or inorganic acids. 1 - Unsubstituted 3:5 - dioxopyrazolidines of genreal formula II above are prepared by condensing a disubstituted malonic acid derivative with hydrazine or a monoalkyl monoaryl or monoacyl hydrazine.
GB16175/58A 1957-05-29 1958-05-20 Improvements in or relating to the preparation of 3:5-diketo-pyrazolidine derivatives Expired GB843993A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH843993X 1957-05-29

Publications (1)

Publication Number Publication Date
GB843993A true GB843993A (en) 1960-08-10

Family

ID=4541616

Family Applications (1)

Application Number Title Priority Date Filing Date
GB16175/58A Expired GB843993A (en) 1957-05-29 1958-05-20 Improvements in or relating to the preparation of 3:5-diketo-pyrazolidine derivatives

Country Status (4)

Country Link
BE (1) BE567877A (en)
CH (1) CH355151A (en)
GB (1) GB843993A (en)
NL (1) NL100004C (en)

Also Published As

Publication number Publication date
NL100004C (en)
CH355151A (en) 1961-06-30
BE567877A (en)

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