ES391125A1 - Procedure for the preparation of beta-fenilsulfiniletil-n, n'-difenilmalono-monohidrazida and its salts. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of beta-fenilsulfiniletil-n, n'-difenilmalono-monohidrazida and its salts. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES391125A1
ES391125A1 ES391125A ES391125A ES391125A1 ES 391125 A1 ES391125 A1 ES 391125A1 ES 391125 A ES391125 A ES 391125A ES 391125 A ES391125 A ES 391125A ES 391125 A1 ES391125 A1 ES 391125A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
translation
salts
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES391125A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of ES391125A1 publication Critical patent/ES391125A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
    • C07C317/08—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/12—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
    • C07C321/18—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Process for the preparation of (Β -phenylsulfinylethyl) -N, N'-diphenyl-malono-monohydrazide and its salts, with organic and inorganic bases, characterized in that a) derivatives of malonic acid are reacted in a manner known per se. of the general formula II **(See formula)** where X and Y can be the same or different and in each case represent a halogen atom, a hydroxy group, an alkoxy group with 1 to 6 carbon atoms, especially a methoxy or ethoxy group, or an aralkoxyloxy group with 7 to 10 carbon atoms, especially a benzyloxy group, with a hydrazine derivative of the general formula III **(See formula)** where R is the acyl group of a saturated or unsaturated aliphatic carboxylic acid with up to 5 carbon atoms or an aroyl group; b) the sulfur atom of the intermediate formed is oxidized to form a sulfinyl group; c) the intermediate product thus obtained is saponified; and if desired d) the reaction product obtained is transformed into the free acid or the desired salt. (Machine-translation by Google Translate, not legally binding)
ES391125A 1970-05-13 1971-05-13 Procedure for the preparation of beta-fenilsulfiniletil-n, n'-difenilmalono-monohidrazida and its salts. (Machine-translation by Google Translate, not legally binding) Expired ES391125A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702023415 DE2023415C3 (en) 1970-05-13 1970-05-13 (beta-Phenylsulfinyl-ethyl) -malonic acid-NjN-miphenylhydrazide and its salts, process for its preparation and medicaments containing them

Publications (1)

Publication Number Publication Date
ES391125A1 true ES391125A1 (en) 1973-07-16

Family

ID=5771017

Family Applications (1)

Application Number Title Priority Date Filing Date
ES391125A Expired ES391125A1 (en) 1970-05-13 1971-05-13 Procedure for the preparation of beta-fenilsulfiniletil-n, n'-difenilmalono-monohidrazida and its salts. (Machine-translation by Google Translate, not legally binding)

Country Status (9)

Country Link
JP (1) JPS5029461B1 (en)
AT (1) AT313257B (en)
BE (1) BE766863A (en)
CH (1) CH550153A (en)
DE (1) DE2023415C3 (en)
ES (1) ES391125A1 (en)
FR (1) FR2100650A1 (en)
NL (1) NL154419B (en)
YU (1) YU34669B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR67999B (en) 1979-05-11 1981-10-26 Ciba Geigy Ag
EP0019586A1 (en) * 1979-05-11 1980-11-26 Ciba-Geigy Ag Antithrombotic combination formulas

Also Published As

Publication number Publication date
DE2023415C3 (en) 1974-10-03
AT313257B (en) 1974-02-11
YU34669B (en) 1979-12-31
BE766863A (en) 1971-11-08
FR2100650A1 (en) 1972-03-24
DE2023415B2 (en) 1974-03-07
CH550153A (en) 1974-06-14
NL154419B (en) 1977-09-15
JPS5029461B1 (en) 1975-09-23
FR2100650B1 (en) 1975-08-01
YU119971A (en) 1979-07-10
NL7106442A (en) 1971-11-16
DE2023415A1 (en) 1971-11-25

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