GB729221A - Steroid - Google Patents

Steroid

Info

Publication number
GB729221A
GB729221A GB17171/52A GB1717152A GB729221A GB 729221 A GB729221 A GB 729221A GB 17171/52 A GB17171/52 A GB 17171/52A GB 1717152 A GB1717152 A GB 1717152A GB 729221 A GB729221 A GB 729221A
Authority
GB
United Kingdom
Prior art keywords
dihydroxyprogesterone
steroid
bromacetamide
tetraone
pregnene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB17171/52A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB729221A publication Critical patent/GB729221A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 4-pregnene-3,6,11,20-tetraone and the preparation thereof by reacting 6,11-dihydroxyprogesterone with more than one equivalent (preferably about two equivalents) of oxidizing agent per mol. of 6,11-dihydroxyprogesterone for a time sufficient to convert to keto the 6- and 11-hydroxy groups without similar conversion elsewhere in the molecule. Suitably, potassium permanganate, N-bromacetamide in t.-butanol, or chromic acid may be used as oxidant.
GB17171/52A 1952-03-25 1952-07-08 Steroid Expired GB729221A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US729221XA 1952-03-25 1952-03-25

Publications (1)

Publication Number Publication Date
GB729221A true GB729221A (en) 1955-05-04

Family

ID=22110566

Family Applications (1)

Application Number Title Priority Date Filing Date
GB17171/52A Expired GB729221A (en) 1952-03-25 1952-07-08 Steroid

Country Status (1)

Country Link
GB (1) GB729221A (en)

Similar Documents

Publication Publication Date Title
GB729221A (en) Steroid
GB1060793A (en) Improvements in or relating to steroids and the manufacture thereof
ES394772A1 (en) 17-chloro steroids
ES371022A1 (en) Di-epoxide process for the preparation of 9{60 -fluoro-16-methylene-prednisolone or-prednisone, and 21-esters thereof
GB716300A (en) Steroids
GB720509A (en) Steroids
GB916951A (en) New process for the preparation of 6ª--fluoro-steroids
GB716299A (en) Steroids
GB932325A (en) Estrane derivatives
GB723749A (en) Steroids
ES391117A1 (en) Novel c-16,17 spiro-orthoester steroids and preparation
GB935610A (en) 3ªá-amino-pregnane compounds
GB916681A (en) Improvements in or relating to androstanone derivatives
GB590310A (en) Production of dicarboxylic acids
GB914784A (en) Improvements relating to steroid compounds and the manufacture thereof
CA486057A (en) Isocinchomeronic acid by oxidation of 2,5-dialkylpyridine with concentrated nitric acid
GB991475A (en) Novel steroid compounds and processes for their production
GB737766A (en) Steroids
GB951474A (en) Improvements in or relating to the bromination of steroid derivatives
GB1001194A (en) Novel des-a steroids and their preparation
GB952492A (en) New steroid compounds and processes for their preparation
ES234653A1 (en) 21-fluoro-9alpha-halo-steroids of the pregnane series
GB749200A (en) Pregnadienes
GB950617A (en) Improvements in or relating to 18,20-oxygenated steroid derivatives
GB713379A (en) Steroids