GB674807A - Compounds of phenyl ethyl barbituric acid with bases and the manufacture thereof - Google Patents

Compounds of phenyl ethyl barbituric acid with bases and the manufacture thereof

Info

Publication number
GB674807A
GB674807A GB26247/50A GB2624750A GB674807A GB 674807 A GB674807 A GB 674807A GB 26247/50 A GB26247/50 A GB 26247/50A GB 2624750 A GB2624750 A GB 2624750A GB 674807 A GB674807 A GB 674807A
Authority
GB
United Kingdom
Prior art keywords
phenyl
propane
amino
acid
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB26247/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Products Ltd
Original Assignee
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Products Ltd filed Critical Roche Products Ltd
Publication of GB674807A publication Critical patent/GB674807A/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises the combination in equimolecular proportions of 5-phenyl-5-ethylbarbituric acid and an organic base of the general formula <FORM:0674807/IV (b)/1> wherein R1, R11, R111 stand for hydrogen o methyl. The compounds may be obtained by reacting the acid and base with or without solvent, e.g. alcohols, acetone, ethyl acetate, ether or chloroform, or by reaction in an organic solvent followed by precipitation by diluting with water or by reacting salts of acid and base. Examples describe the preparation of salts of 5-phenyl-5-ethyl-barbituric acid with (1) 1-phenyl-2-amino-propane; (2) 1-(31,41 - dimethyl - phenyl) - 2 - amino - propane (from the corresponding sodium salt and hydrobromide respectively); (3) 1-phenyl-2-methyl-amino-propane; (4) 1-(41-methyl-phenyl)-2-amino-propane.
GB26247/50A 1949-11-09 1950-10-27 Compounds of phenyl ethyl barbituric acid with bases and the manufacture thereof Expired GB674807A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH674807X 1949-11-09

Publications (1)

Publication Number Publication Date
GB674807A true GB674807A (en) 1952-07-02

Family

ID=4528004

Family Applications (1)

Application Number Title Priority Date Filing Date
GB26247/50A Expired GB674807A (en) 1949-11-09 1950-10-27 Compounds of phenyl ethyl barbituric acid with bases and the manufacture thereof

Country Status (1)

Country Link
GB (1) GB674807A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3210247A (en) * 1960-04-16 1965-10-05 Anti-epileptic i-cyclohexyl-z-methyl- aiviino propane salt of phenyl ethyl barbituric acid
WO1999025699A1 (en) * 1997-11-19 1999-05-27 Tets, Viktor Veniaminoich Salts of 5,5'-arylidenebisbarbituric and 5,5'-arylidenebis(2-thiobarbituric) acids and 5,5'-arylidenebis(2-thiobarbituric) acids having an antibacterial, anti-chlamydial, antiviral and immuno-modulating activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3210247A (en) * 1960-04-16 1965-10-05 Anti-epileptic i-cyclohexyl-z-methyl- aiviino propane salt of phenyl ethyl barbituric acid
WO1999025699A1 (en) * 1997-11-19 1999-05-27 Tets, Viktor Veniaminoich Salts of 5,5'-arylidenebisbarbituric and 5,5'-arylidenebis(2-thiobarbituric) acids and 5,5'-arylidenebis(2-thiobarbituric) acids having an antibacterial, anti-chlamydial, antiviral and immuno-modulating activity

Similar Documents

Publication Publication Date Title
GB1033777A (en) Bis-anilide derivatives
GB674807A (en) Compounds of phenyl ethyl barbituric acid with bases and the manufacture thereof
GB628410A (en) A process for the manufacture of isoalloxazines
GB680952A (en) Improvements in new morphine derivatives and production thereof
GB757137A (en) New adrenochrome derivative and process for its production
GB740130A (en) Derivatives of 4-cyclohexyl-cyclohexanone and process for the manufacture thereof
GB672164A (en) A process for the manufacture of pentaenes
US2354784A (en) Substituted p-p&#39;-diamino diphenyl sulphones and a process of making the same
GB677540A (en) Improvements in or relating to the manufacture of benziminazoles
GB959993A (en) Camphor derivatives
GB727007A (en) New semicarbazones
GB843908A (en) Novel morphinan derivatives and the manufacture thereof
GB888968A (en) Improvements in or relating to tetracycline derivatives
GB679894A (en) Production of thiosemicarbazones
Rudolf et al. Substituted p-p'-diamino diphenyl sulphones and a process of making the same
GB750194A (en) Isonicotinamides
GB873781A (en) Novel sulphanilamido-pyrimidines and acid addition salts thereof and a process for the manufacture of same
GB621231A (en) The manufacture of tertiary carbinols
ES426948A1 (en) Procedure for the preparation of new 1,4-benzodiazepinas. (Machine-translation by Google Translate, not legally binding)
GB837008A (en) Basically substituted butyric acid amides and a process for their manufacture
GB773862A (en) New isonicotinylhydrazide derivative and process for its preparation
GB673623A (en) Manufacture of pyrazolones
GR20636B (en) METHOD FOR THE PREPARATION OF NEW ORGANIC COMPOSITIONS.
GB1026508A (en) Benzenesulphonyl-semicarbazides and process for their manufacture
GB1021385A (en) Derivatives of 2-oxo-2h-1,4-benzoxazine