GB667039A - Improvements in and relating to the manufacture of preparations containing the anti-pernicious anaemia factor - Google Patents

Improvements in and relating to the manufacture of preparations containing the anti-pernicious anaemia factor

Info

Publication number
GB667039A
GB667039A GB1851749A GB1851749A GB667039A GB 667039 A GB667039 A GB 667039A GB 1851749 A GB1851749 A GB 1851749A GB 1851749 A GB1851749 A GB 1851749A GB 667039 A GB667039 A GB 667039A
Authority
GB
United Kingdom
Prior art keywords
extract
relating
factor
manufacture
preparations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1851749A
Inventor
Ernest Lester Smith
Stanley Ball
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Priority to GB1851749A priority Critical patent/GB667039A/en
Publication of GB667039A publication Critical patent/GB667039A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

In a process for removing impurities from an extract containing material having anti-pernicious an mia activity, e.g. an extract of liver or prepared from micro-organisms, the extract is treated with nitrous acid. The acidic impurities may be removed by means of an organic solvent, e.g. ether, chloroform, lower aliphatic esters, and butyl and amyl alcohols from the resulting solution, or alternatively by anion-exchange resins. Alternatively the active material may be extracted from the solution resulting from the nitrous acid treatment by rendering the latter neutral or alkaline and extracting with a suitable solvent. Detailed examples are given. Specifications 469,430 and 665,485 are referred to.
GB1851749A 1949-07-13 1949-07-13 Improvements in and relating to the manufacture of preparations containing the anti-pernicious anaemia factor Expired GB667039A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1851749A GB667039A (en) 1949-07-13 1949-07-13 Improvements in and relating to the manufacture of preparations containing the anti-pernicious anaemia factor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1851749A GB667039A (en) 1949-07-13 1949-07-13 Improvements in and relating to the manufacture of preparations containing the anti-pernicious anaemia factor

Publications (1)

Publication Number Publication Date
GB667039A true GB667039A (en) 1952-02-20

Family

ID=10113792

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1851749A Expired GB667039A (en) 1949-07-13 1949-07-13 Improvements in and relating to the manufacture of preparations containing the anti-pernicious anaemia factor

Country Status (1)

Country Link
GB (1) GB667039A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE945649C (en) * 1953-01-06 1956-07-12 Hoechst Ag Process for fortifying vitamin B.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE945649C (en) * 1953-01-06 1956-07-12 Hoechst Ag Process for fortifying vitamin B.

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