GB607258A - The manufacture of substituted benzhydryl ethers - Google Patents

The manufacture of substituted benzhydryl ethers

Info

Publication number
GB607258A
GB607258A GB291846A GB291846A GB607258A GB 607258 A GB607258 A GB 607258A GB 291846 A GB291846 A GB 291846A GB 291846 A GB291846 A GB 291846A GB 607258 A GB607258 A GB 607258A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
same
manufacture
morpholine
substituted benzhydryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB291846A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Priority to GB291846A priority Critical patent/GB607258A/en
Priority to US688421A priority patent/US2567351A/en
Publication of GB607258A publication Critical patent/GB607258A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Compounds of the general formula <FORM:0607258/IV(b)/1> n which R1 and R2 are the same or different substituents and represent hydrogen, an alkyl or an alkoxy radical containing 1 or 2 carbon atoms, R3 and R4 are the same or different alkyl radicals containing 1 to 3 carbon atoms or may form part of a saturated ring such as piperidine, morpholine, a methyl substituted morpholine or thiomorpholine are obtained by reacting a benzhydryl halide, e.g. the bromide with an aminoalcohol of the formula <FORM:0607258/IV(b)/2> Benzene, toluene, xylene, turpentine, a -pinene, b -penene dipentene and p-cymene may be used as solvents. Preferably, the reaction is carried out at approximately 100 DEG C. Detailed examples are given of the preparation of b -dimethylaminoethyl, b - N - piperidylethyl, b - N - morpholinylethyl, b -diethylaminoethyl, di-n-propylaminoethyl-p.p1-dimethyl and b -methylethylaminoethyl-o-methoxybenzhydryl ether.
GB291846A 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers Expired GB607258A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB291846A GB607258A (en) 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers
US688421A US2567351A (en) 1946-01-29 1946-08-05 Process for the manufacture of benzhydryl ethers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB291846A GB607258A (en) 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers

Publications (1)

Publication Number Publication Date
GB607258A true GB607258A (en) 1948-08-27

Family

ID=9748525

Family Applications (1)

Application Number Title Priority Date Filing Date
GB291846A Expired GB607258A (en) 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers

Country Status (1)

Country Link
GB (1) GB607258A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1087618B (en) * 1952-04-08 1960-08-25 Konink Pharmaceutischie Fabrie Process for the production of new dialkylaminoalkyl (benzhydryl) ethers with local anesthetics and atropine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1087618B (en) * 1952-04-08 1960-08-25 Konink Pharmaceutischie Fabrie Process for the production of new dialkylaminoalkyl (benzhydryl) ethers with local anesthetics and atropine

Similar Documents

Publication Publication Date Title
GB851311A (en) Morpholine compounds and their production
GB607258A (en) The manufacture of substituted benzhydryl ethers
SE7601206L (en) ACETYLENE DERIVATIVES
GB605916A (en) The manufacture of substituted benzhydryl ethers
GB606158A (en) The manufacture of substituted benzhydryl ethers
GB605915A (en) The manufacture of substituted benzhydryl ethers
GB1121140A (en) Process for preparing 3-aminoisoxazole derivatives
GB661537A (en) Improvements in and relating to the preparation of sulphonyl derivatives of piperazine
GB860860A (en) Substituted terpenes
GB606317A (en) The manufacture of substituted benzhydryl ethers
GB956594A (en) Bis-(ª‡-hydroxy-ª‡-arylaminoacetyl)-aryl derivatives
GB650911A (en) Improvements in or relating to 3-pyrazolidone compounds
GB609455A (en) Quaternary ammonium halides and methods for obtaining the same
GB826533A (en) Naphthoquinone derivatives
GB1016088A (en) New 7-hydroxychromone derivatives
GB639217A (en) Tertiary amines and methods for obtaining the same
GB1444967A (en) Pyrocatechol ethers
GB686069A (en) New phenthiazine derivatives and process for their preparation
GB938646A (en) New piperazine derivatives
GB1060263A (en) Benzenesulphonyl isourea ethers and a process for their manufacture
GB632277A (en) Improvements in or relating to the preparation of derivatives of phenthiazine
GB699547A (en) Improvements relating to 1-dialkylcarbamyl-4-methyl piperazine mono-oxides
GB647759A (en) Improvements in the manufacture of stilbene derivatives
ES272000A1 (en) Procedure for the preparation of new derivatives of cumarina (Machine-translation by Google Translate, not legally binding)
GB683594A (en) The manufacture of substituted iminazoles