GB606317A - The manufacture of substituted benzhydryl ethers - Google Patents

The manufacture of substituted benzhydryl ethers

Info

Publication number
GB606317A
GB606317A GB291646A GB291646A GB606317A GB 606317 A GB606317 A GB 606317A GB 291646 A GB291646 A GB 291646A GB 291646 A GB291646 A GB 291646A GB 606317 A GB606317 A GB 606317A
Authority
GB
United Kingdom
Prior art keywords
carbonate
oxide
carbon atoms
metal hydroxide
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB291646A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parke Davis and Co LLC
Original Assignee
Parke Davis and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC
Priority to GB291646A priority Critical patent/GB606317A/en
Publication of GB606317A publication Critical patent/GB606317A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

Compounds of the general formula <FORM:0606317/IV(b)/1> in which R1 and R2 are the same or different substituents and represent hydrogen, an alkyl or an alkoxy radical containing 1 or 2 carbon atoms, R3 and R4 are the same or different alkyl radicals containing 1 to 3 carbon atoms or may form part of a saturated ring such as piperidine, morpholine, a methyl substituted morpholine or thiomorpholine are obtained by reacting a haloether with an amine of the formula <FORM:0606317/IV(b)/2> An acid-binding agent such as an alkali metal hydroxide, oxide, alcoholate, carbonate, bicarbonate or acetate or an alkaline earth metal hydroxide, oxide or carbonate may be employed. Detailed examples are given of the preparation of b -dimethylaminoethyl, b -N-piperidinoethyl, b -N-(morpholinoethyl), b -diethylaminoethyl, b -di-n-propylaminoethyl-p.p1-dimethyl, b -methylethylaminoethyl o-methoxy, b -methylaminoethyl and b -isopropylaminoethyl benzhydryl ether.
GB291646A 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers Expired GB606317A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB291646A GB606317A (en) 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB291646A GB606317A (en) 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers

Publications (1)

Publication Number Publication Date
GB606317A true GB606317A (en) 1948-08-11

Family

ID=9748490

Family Applications (1)

Application Number Title Priority Date Filing Date
GB291646A Expired GB606317A (en) 1946-01-29 1946-01-29 The manufacture of substituted benzhydryl ethers

Country Status (1)

Country Link
GB (1) GB606317A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1087618B (en) * 1952-04-08 1960-08-25 Konink Pharmaceutischie Fabrie Process for the production of new dialkylaminoalkyl (benzhydryl) ethers with local anesthetics and atropine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1087618B (en) * 1952-04-08 1960-08-25 Konink Pharmaceutischie Fabrie Process for the production of new dialkylaminoalkyl (benzhydryl) ethers with local anesthetics and atropine

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